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An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic mechanisms that drive AGS and test strategies to inhibit the condition using existing drugs.

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A little-studied gene may explain how some liver cancer cells obtain the nutrition they need to proliferate, according to new research from the University of Maryland.

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School-based mental health programs can reach large numbers of children, with increasing evidence of effectiveness in improving mental health and related outcomes, according to a research review in the September/October issue of the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

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Fred Hutchinson Cancer Research Center is launching a new integrated research center to prevent and find cures for cancers caused by infectious agents. It will be led by Dr. Denise Galloway, a Fred Hutch microbiologist whose research paved the way for the HPV vaccine, which prevents cervical, throat and other cancers.

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Currently, testing for Zika requires that a blood sample be refrigerated and shipped to a medical center or laboratory, delaying diagnosis and possible treatment. Now, Washington University in St. Louis researchers have developed a test that quickly can detect the presence of Zika virus in blood. Although the new proof-of-concept technology has yet to be produced for use in medical situations, test results can be determined in minutes, and the materials do not require refrigeration.

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Athletes at all levels are pressured to be physically superior, which can cause many to overlook their mental health needs.

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Undergraduate summer research fellowships let students pursue their passions. Daniel Craven used a BioBots three-dimensional bioprinter to make small polymer scaffolds that can hold cells for tissue engineering. The scaffolds, less than half an inch thick, are biocompatible and biodegradable.

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An analysis of U.S. government data obtained by Northwestern University’s Deportation Research Clinic shows that the U.S. government detained more than 260 U.S. citizens for weeks and even years, most in private prisons under contract with Immigration and Customs Enforcement (ICE).

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Researchers have created a small molecule that prevents or impedes tooth cavities in a preclinical model. The inhibitor blocks the function of a key virulence enzyme in an oral bacterium, a molecular sabotage that is akin to throwing a monkey wrench into machinery to jam the gears.

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B-Line Medical’s SimCapture and LiveCapture products are in use at 14 of 20 U.S. News & World Report best hospitals

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This is a continuing profile series on the directors of the Department of Energy (DOE) Office of Science User Facilities. These scientists lead a variety of research institutions that provide researchers with the most advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nano world, the environment, and the atmosphere.

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The American Thoracic Society is extremely disappointed with the Department of Transportation’s decision to withdraw an advance notice of a proposed rule regarding screening commercial truck drivers and train engineers for sleep apnea. Abundant evidence indicates that undiagnosed or untreated sleep apnea is the root cause of many preventable fatal and non-fatal driving-related accidents.

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Researchers at the University of Wisconsin-Madison have developed a new measurement for the volume and activity of beta cells, the source of the sugar-regulating hormone insulin.

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It is that time of year for kids returning to school to get vaccinated before the school year starts. But the controversy over the HPV vaccine continues to rage as it has since its introduction in the U.S. in 2014.

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Give your medicine a jolt. By using – electrochemistry – a technique that combines electricity and chemistry, future pharmaceuticals – including many of the top prescribed medications in the United States – soon may be easily scaled up to be manufactured in a more sustainable way.

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Researchers have developed a new methodology for identifying disease-causing genetic mutations in the non-coding region of the genome. This portion of the genome has remained uninterpretable until now.

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A team from the Salk Institute for Biological Studies and the University of California San Diego has, for the first time, profiled chemical modifications in the DNA of individual neurons, giving the most detailed information yet on what makes one brain cell different from its neighbor.

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Proteins in archaea bend strands of DNA in a way that’s similar in eukaryotes, new research from HHMI investigator and colleagues reveals. That similarity hints at the evolutionary origin of the elaborate folding that eukaryotic cells use to cram their genome into a nucleus.