Feature Channels: Women's Health

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Key differences in male and female mice brains provide new insights into how sex determines the mechanisms by which distinct synapses monitor and regulate dopamine signaling. The impact of sex differences is particularly pronounced when the mice express a human genetic variant found in boys with either ADHD or autism. Behavioral generalizations across the sexes may limit diagnosis of mental illness, especially if one sex translates alterations into outward signs such as hyperactivity and aggression vs. more internal manifestations such as learning, memory and mood, even when the same molecular pathology is at work.

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Dr. Colleen McCormick joins the University of New Mexico Comprehensive Cancer Center. Her curiosity and desire to work with patients from the beginning of their diagnosis to the end of their care led her to gynecologic oncology.

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Adolescent and young adult women who were diagnosed with cancer and received chemotherapy treatment prior to pregnancy did not have a higher risk of stillbirth, according to research led by Caitlin C. Murphy, PhD, MPH, with UTHealth Houston.

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The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), has awarded Jonathan Backer, M.D., professor and chair of molecular pharmacology at Albert Einstein College of Medicine and associate director for shared resources at Montefiore Einstein Cancer Center (MECC), a five-year, $10 million team science (P01) grant to investigate the mechanisms regulating cancer cells that seed tumors in the lungs, a key metastatic site for breast cancer.

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A two-pronged approach to imaging breast density in mice, developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, resulted in better detection of changes in breast tissue, including spotting early signs of cancer. The researchers hope that this approach will be translated from mice and improve breast imaging for people; it may also help with prognosis of disease as density can be linked to specific patterns of mammary gland growth, including signs of cancer development.

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Según los investigadores de Mayo Clinic, las mujeres con antecedentes de preeclampsia grave tienen más indicadores de un mayor riesgo de sufrir daño e inflamación en las células del cerebro en comparación con aquellas que tuvieron embarazos sin complicaciones.

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Pesquisadores da Mayo Clinic descobriram que mulheres com histórico de pré-eclâmpsia grave têm mais indicadores de maior risco de danos e inflamação das células cerebrais em comparação com mulheres que tiveram gestações sem complicações.

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Women’s mental health was more likely to be affected by physical exercise frequency during the COVID-19 pandemic than men’s, according to new research from Binghamton University, State University of New York.

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Patients who received trastuzumab deruxtecan (T-DXd) for human epidermal growth factor receptor 2 (HER2)-low metastatic breast cancer reported that the treatment maintained their quality of life (QoL) compared to conventional chemotherapy, according to results presented today by researchers from The University of Texas MD Anderson Cancer Center at the European Society for Medical Oncology (ESMO) Congress 2022.

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The global study assessed risk factors, including metabolic (such as high blood pressure, obesity and diabetes), behavioural (smoking and diet), and psychosocial (economic status and depression) in about 156,000 people without a history of CVD between the ages of 35 and 70. Living in 21 low, middle and high-income countries on five continents, they were followed for an average of 10 years.

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A new report finds physical and sexual violence are an increasing ‘epidemic’ in California; UC San Diego researchers call for health equity-based reform.

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A published study of 1,899 pregnant women nationwide representing all 50 states reveals that during the Covid-19 pandemic if a pregnant woman had lower socioeconomic status and/or were African American, she was less likely to have the intention of taking a Covid-19 vaccine or actually receiving it.

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Amid growing scrutiny of breast implant safety, a pair of UCLA scientists are developing a lab test aimed at detecting silicone implant ruptures which they think may also help explain why many women who received implants have later reported a constellation of systemic symptoms.

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The latest research and expert commentary on pain management.

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Children of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD) compared to those whose mothers did not have obesity, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Prenatal stress was unrelated to the timing of the pandemic, study found

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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The unprecedented infant formula shortage created an alarming problem for parents across the country. The majority of US infants are partially or entirely reliant on infant formula for nutrition, with only one in four infants exclusively breastfed for the first six months of life. The study, which enrolled a sample of predominantly non-Hispanic white and highly educated women in Washington D.C., found that the shortage had adverse impacts on mothers’ mental and emotional health, had significant financial costs, and led to changes in infant feeding practices.

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September is gynecologic cancer awareness month. The empowerment of taking charge of your gynecologic health starts with having the right information and resources, knowing your body and talking openly to your doctors—and each other—about critical health issues.

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Combination therapies show encouraging results in several studies led by Dana-Farber Cancer Institute and presented for the first time at the European Society of Medical Oncology (ESMO) Congress 2022, Paris, France. The studies will be presented both in-person and online on September 9-13, 2022.

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Premenstrual mood swings and anxiety are so common – experienced by more than 64% of women – that they represent a “key public health issue globally,” according to a new UVA Health study.

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Symptoms are subjective experiences that may indicate underlying cardiovascular disease or change therein and are of fundamental significance not only to the diagnosis of cardiovascular disease (CVD) and appraisal of response to medical therapy but also directly to patients’ daily lives.

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Podcast interview with Sean Devine, whose research found that women's judgments about other women's bodies can be biased by an overrepresentation of thinness.

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Chad Hamilton, M.D., Associate Research Director for the Ochsner Cancer Institute is available to comment on gynecologic cancers, treatments, and research.

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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Hospitalizations that occur during pregnancy, but before giving birth and those that occur in the postpartum period, made up over half of in-hospital maternal deaths between 2017-2019, a new study reveals.

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The latest research on plants brought to you by Newswise.

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New research from the Smidt Heart Institute at Cedars-Sinai demonstrated that women—when height is accounted for—have a 50% higher risk of developing the abnormal heart rhythm disturbance when compared to men.

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Nipple-sparing techniques can provide better outcomes for women undergoing breast reconstruction after mastectomy – but due to complication risks, these approaches are often not offered to women with sagging or larger breasts. For this group of patients, a 'batwing' incision may provide a safer option to nipple-sparing mastectomy (NSM), reports a study in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). Plastic and Reconstructive Surgery® is published in the Lippincott portfolio by Wolters Kluwer.

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The human papillomavirus (HPV) vaccine is safe and effective – but it’s not for everyone. Michelle Ozbun, PhD, and her team at UNM Cancer Center published a research article earlier this year in Antimicrobial Agents and Chemotherapy in which they describe how a drug called protamine sulfate blocks HPV infection. Like a game of musical chairs among molecules, the drug molecules bind to heparan sulfate cell receptors, preventing HPV virus particles from doing so.

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Mayo Clinic researchers have found that using artificial intelligence (AI) algorithms to analyze patterns of changes in women who are in labor can help identify whether a successful vaginal delivery will occur with good outcomes for mom and baby. The findings were published in PLOS ONE.

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Pulling from extensive interviews, the latest research and national data, Sociology Professor Susan Stewart says women are drinking more alcohol to cope with stress, move up at work, feel confident and have fun – or be perceived as having fun – in her new book “On the Rocks: Straight talk about women and drinking.”

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UCLA research finds that a refundable State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC was associated with a 21% relative risk reduction in reported behavior that could put single mothers at high risk for becoming infected with HIV during the previous year. Also, a 10 percentage-point increase in SEITC was linked to a 38% relative reduction in the same reported high-risk behavior the previous year.

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Following Enhanced Recovery After Surgery (ERAS) protocols designed to minimize surgical stress results in improved patient recovery and satisfaction, reduced postoperative complications, and shorter hospital stays, according to a review of ERAS programs in minimally invasive gynecologic surgery by UT Southwestern researchers.

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High blood pressure in pregnancy is increasing and a leading cause of maternal death

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A new study identified multiple risk factors, including high utility bills, employment hardship, and medical hardship, that may lead to food insecurity among mothers of young children, according to researchers at UTHealth Houston.