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More Power to the Mitochondria: Cells' Energy Plant Also Plays Key Role in Stem Cell Development

Researchers at NYU Langone Medical Center have discovered that mitochondria, the major energy source for most cells, also play an important role in stem cell development — a purpose notably distinct from the tiny organelle’s traditional job as the cell’s main source of the adenosine triphosphate (ATP) energy needed for routine cell metabolism.

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Dead Feeder Cells Support Stem Cell Growth

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Stem cells naturally cling to feeder cells as they grow in petri dishes. Scientists have thought for years that this attachment occurs because feeder cells serve as a support system, providing stems cells with essential nutrients.

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Oral Milk Thistle Extract Stops Colorectal Cancer Stem Cells From Growing Tumors

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"It's very simple: tumors from mice that were initially fed silibinin had fewer cancer stem cells, were smaller, had lower metabolisms and showed decreased growth of new blood vessels," says University of Colorado Cancer Center researcher.

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Drugs Stimulate Body’s Own Stem Cells to Replace the Brain Cells Lost in Multiple Sclerosis

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Led by Case Western Reserve researchers, a multi-institutional team identified two topical drugs (miconazole and clobetasol) capable of stimulating regeneration of damaged brain cells and reversing paralysis in animal models of MS. The results appear online Monday, April 20, in the journal Nature.

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Trending Stories Report for 15 April 2015

Trending news releases with the most views in a single day. Topics include: robotics, nicotine and alcohol, stem cells, vision, cancer, pregnancy, racial disparities in smoking risk, and herbal therapy for cardiac hypertrophy

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A New Tool for Understanding ALS: Patients’ Brain Cells

Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited those human-made cells into the first public ALS cell library, enabling scientists to better study the disease.

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Stem Cell Injection May Soon Reverse Vision Loss Caused By Age-Related Macular Degeneration

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65.

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U-M Researchers Find New Gene Involved in Blood-Forming Stem Cells

Research led by the University of Michigan Life Sciences Institute has identified a gene critical to controlling the body's ability to create blood cells and immune cells from blood-forming stem cells—known as hematopoietic stem cells.

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Researchers Identify Drug Target for ATRA, the First Precision Cancer Therapy

Cancerous tumors have the ability to evade targeted therapies by activating alternative pathways. Tumors also contain cancer stem cells, believed responsible for metastasis and drug resistance. Now scientists in the Cancer Research Institute at Beth Israel Deaconess Medical Center have identified a drug target that addresses both of these challenges.

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Stem Cell Disease Model Clarifies Bone Cancer Trigger

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers.