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Reporter Needed to Cover New 'Fast Pitch' Service from Newswise

Newswise Fast Pitch is the first service to invite reporters and communications people to meet via video conference and pitch story ideas. Reporters are highly satisfied with the results.

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Stem Cell Treatment for Lou Gehrig’s Disease May Be Safe

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, suggests that transplanting human stem cells into the spinal cord may be done safely. The research is published in the June 29, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study was not designed to determine whether the treatment was effective, researchers noted that it did not slow down the progression of the disease.

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New Way Out: Researchers Show How Stem Cells Exit Bloodstream

Researchers have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought. This process, dubbed angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies, but also metastatic cancers.

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Non-Healing Tissue From Diabetic Foot Ulcers Reprogrammed as Pluripotent Stem Cells

Researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts, led by Jonathan Garlick, have established for the first time that skin cells from diabetic foot ulcers can be reprogrammed to acquire properties of embryonic-like cells.

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Mutant Enzyme Study Aids in Understanding of Sirtuin’s Functions

The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of Cornell University researchers has devised a method for isolating one specific enzyme activity to determine its contribution and lead to better overall understanding of SIRT6.

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A New Bio-Ink for 3-D Printing with Stem Cells

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The new stem cell-containing bio ink allows 3D printing of living tissue, known as bio-printing.

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Starving Stem Cells May Enable Scientists to Build Better Blood Vessels

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Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.

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Zika Mosquitoes Differ From West Nile Mosquitoes; First Zika Vaccine to Be Tested in Human Clinical Trial; Potential Drug Target Identified for Zika, and MORE in the Zika Virus News Source

Go here for the latest research, experts and features on Zika in the Zika Virus News Source

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Four NCI Cancer Centers Announce Landmark Research Consortium and Collaborations with Celgene

Today, The Abramson Cancer Center at the University of Pennsylvania, The Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, and The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai announced the establishment of a research consortium focused on accelerating the discovery and development of novel cancer therapeutics and diagnostics for the benefit of patients.

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Autologous Stem Cell Transplantation Offers Safe and Effective, and Potentially Curative, Option for Patients with HIV-Associated Lymphoma

Multicenter, phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed/treatment-resistant lymphoma.

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Lab-Grown Nerve Cells Make Heart Cells Throb

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions. Because the heart-thumping nerve cells were derived from induced pluripotent stem (iPS) cells, the researchers believe the cells — known as sympathetic nerve cells — will allow them to grow nerve cells that replicate particular patients’ diseases of the nervous system.

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Face of the Future

A new technique developed at Columbia Engineering by Biomedical Engineering Professor Gordana Vunjak-Novakovic repairs large bone defects in the head and face by using lab-grown living bone, tailored to the patient and the defect being treated. This is the first time researchers have grown living bone grown to precisely replicate the original anatomical structure, using autologous stem cells derived from a small sample of the recipient’s fat. (Science Translational Medicine 6/15)

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Regenerating Memory with Neural Stem Cells

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Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function. Someday, though, we may actually be able to replace brain cells and restore memory.

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Texan Is First Adult in U.S. To Receive Updated Stem Cell Transplant for Leukemia Treatment at UT Southwestern

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Texan Chuck Dandridge became the first adult in the U.S. to receive a newly modified stem cell transplant that uses genetically engineered blood cells from a family member, announced researchers at UT Southwestern Medical Center’s Harold C. Simmons Comprehensive Cancer Center where the procedure was performed.

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Healing the Heart From Within

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Babies born with heart defects live longer than ever thanks to advances in the diagnosis and treatment of congenital heart disease. Yet, despite substantial progress, many continue to face bleak odds, lifelong medication, multiple surgeries and progressive heart failure, often requiring a transplant.

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Body’s Own Gene Editing System Generates Leukemia Stem Cells

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Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers at University of California San Diego School of Medicine have now unraveled how pre-leukemic white blood cell precursors become leukemia stem cells.

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Study Sets Standards for Evaluating Pluripotent Stem Cell Quality

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As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use. In a study published June 9 by the journal Stem Cell Reports, the multi-institutional research team reports on the comprehensive characterization of a large set of induced pluripotent stem cells (iPSCs).

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Stem Cells Shown Safe, Beneficial for Chronic Stroke Patients

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People disabled by a stroke demonstrated substantial recovery long after the event when modified adult stem cells were injected into their brains.

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New Clues Found to Immune System’s Misfiring in Autoimmune Diseases; Brain Power; Converting Cirrhosis-Causing Cells to Healthy Liver Cells in Mice, and More in the Cell Biology News Source

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Researchers Convert Cirrhosis-Causing Cells to Healthy Liver Cells in Mice

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UCSF researchers that it is possible to generate healthy new liver cells in the livers of living mice by converting the very cells that drive liver disease, thereby reducing liver damage and improving liver function at the same time.