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Article ID: 693183

Scientists have re-created brain neurons of obese patients using "disease in a dish" technology, offering a new method to study the brain's role in obesity and possibly help tailor treatments to specific individuals.

Article ID: 693021

Clinical trial planning is underway at MedStar Heart & Vascular Institute to determine whether a novel stem cell therapy will improve heart function for patients with heart failure.

Article ID: 693020

Investigators at Cedars-Sinai are exploring a new way to treat amyotrophic lateral sclerosis (ALS) by transplanting specially engineered neural cells into the brain. Their new study shows the transplanted cells delayed disease progression and extended survival in animal models.

Article ID: 692193

Cells acquire distinct fates and functions during development. A study from the IMBA reveals a new mechanism of cell fate specification involving the regulation of cell metabolism.

Article ID: 692188

Physicians and researchers at the USC Roski Eye Institute have collaborated with other California institutions to show that a first-in-kind stem cell–based retinal implant is feasible for use in people with advanced dry age-related macular degeneration.

Article ID: 692112

Researchers have developed a radically new approach to growing in the lab adult-like human heart muscle from human induced pluripotent stem cells in only four weeks. They compressed the development timeframe into a faster, more complete transition to cardiac maturity than any other team has done so far. They formed cardiac tissues from early-stage iPSC-derived cardiomyocytes, soon after the initiation of spontaneous contractions, by subjecting the cells encapsulated in hydrogel to increasingly intense physical conditioning.

Article ID: 692222

Evan Y. Snyder, M.D., Ph.D., professor and founding director, Center for Stem Cells & Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute (SBP) and professor at the University of California San Diego, has been elected to membership in the Association of American Physicians (AAP).

Article ID: 691952

A team of computational biologists has developed an algorithm that can ‘align’ multiple sequencing datasets with single-cell resolution. The new method has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.

Article ID: 691537

Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.

Article ID: 691388

Three tumor samples collected over time from a single patient show how cancer evolves in response to treatment.