EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 11/23/2009 5:00 AM EST

Cancer-Fighting Drugs Delivered Right to the Tumor

An encapsulation breakthrough may enable doctors to deliver anti-cancer drugs directly to tumors over extended time periods, while preventing the side effects of chemo and other cancer treatments. The system led to an 87% reduction in volume and an 83% reduction in weight of a treated glioma tumor in mice after two weeks.

View

Scientists Successfully Reprogram Blood Cells to Correct Lysosomal Storage Disease

Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme – preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler’s syndrome.

View

Scientists Reveal How Induced Pluripotent Stem Cells Differ from Embryonic Stem Cells and Tissue of Derivation

The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research from Johns Hopkins and Harvard.

View

Of Mice and Men: Stem Cells and Ethical Uncertainties

The recent creation of live mice from induced pluripotent stem cells (iPSCs) not only represents a remarkable scientific achievement, but also raises important issues, according to bioethicists at The Johns Hopkins University's Berman Institute of Bioethics.

View

USC Physician-Researchers Receive $16 Million Grant From State Stem Cell Agency

Physician-researchers at the University of Southern California (USC) received a nearly $16 million grant from the California Institute for Regenerative Medicine (CIRM) to fund the development of a stem cell-based treatment for age-related macular degeneration, the leading cause of vision loss and blindness among the elderly.

View

Cedars-Sinai Researchers Awarded $5.5 Million To Develop Novel Stem Cell Treatments for Heart Attack Patients

A team of Cedars-Sinai Heart Institute stem cell researchers led by Eduardo Marbán, M.D., Ph.D. has been awarded a four-year, $5.5 million grant from the California Institute of Regenerative Medicine (CIRM) to fund research leading to clinical trials of new treatments for heart attack patients.

View

$20 Million Stem Cell Grant for UC San Diego Cancer Research

Researchers led by Moores UCSD Cancer Center Director Dennis A. Carson, MD, professor of medicine, and Catriona Jamieson, MD, PhD, assistant professor of medicine and director of the Cancer Stem Cell Research Program at the Moores UCSD Cancer Center have been awarded $20 million over four years to develop novel drugs against leukemia stem cells.

View

Stem Cell Therapy May Offer Hope for Acute Lung Injury

Researchers at the University of Illinois at Chicago College of Medicine have shown that adult stem cells from bone marrow can prevent acute lung injury in a mouse model of the disease.

View

Salk Institute Scientist Receives $15.6 Million CIRM Disease Team Award to Develop Novel Stem-Cell Derived Therapy for Lou Gehrig’s Disease

The Salk Institute has been awarded a $15.6 million grant by the California Institute for Regenerative Medicine (CIRM) for translational research focusing on developing a novel stem-cell based therapy for Amyotrophic Lateral Sclerosis (ALS) – or Lou Gehrig’s Disease.

View