Feature Channels:
Stem Cells
Filters:
MedicineChannels:Fertility, sex-linked conditions, Urogenital System, Sperm, Stem Cells, Genetics, Cell Biology, Male Infertility |
The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers at University of California San Diego School of Medicine determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others — drive the development of stem cells in the testes in mice. The investigators also linked RHOX gene mutations to male infertility in humans. |
Released: 27-Sep-2016 12:05 PM EDT
University of California San Diego Health Sciences |
MedicineChannels:Cirm, California Institute For Regenerative Medicine, University of California at San Diego, UCSD, Stem Cell, Stem Cell Research, C. Randal Mills, Ph.D., Cystonisis, Blood Stem Cells, Stephanie Cherqui, FDA, Food And Drug Administration, Cysteine |
Cystinosis is a rare disease that usually strikes children before they are two years old and can lead to end stage kidney failure before their tenth birthday. Current treatments are limited, which is why the CIRM Board today approved $5.2 million for research that holds the possibility of a safe, effective, one-time life-long treatment. |
Released: 21-Sep-2016 2:05 PM EDT
California Institute for Regenerative Medicine (CIRM) |
MedicineChannels:Heart Attack, Heart Failure, Heart Disease, Biomedical Engineering, Stem Cells, Progenitor Cells |
To prevent heart failure and restore heart function, researchers will work to create a bioengineered, human heart-tissue patch that is large, standardized and highly functional. This preclinical work will be supported by a seven-year grant just awarded by the NHLBI. |
Released: 21-Sep-2016 1:05 PM EDT
University of Alabama at Birmingham |
MedicineChannels:Stem Cells, Animal Research, Animal Studies, Heart, Heart Cells, Medicine |
The promise of stem cells to treat cardiovascular disease may soon be a step closer to clinical application as scientists from three institutions seek to perfect and test three-dimensional “heart patches” in a large animal model — the last big hurdle before trials in human patients. |
Released: 21-Sep-2016 1:05 PM EDT
University of Wisconsin-Madison |
MedicineChannels:induced pluripotent stem (iPS) cells, Reprogramming, Bromodomains, BET bromodomains, JQ1, Stem Cells |
Cells use specific proteins that help the cell remember what collection of genes needs to be turned on again after cell division. Removing these transcriptional bookmarks may be a key to better reprogramming of human fibroblasts to create induced pluripotent stem cells, or iPSCs. |
Embargo expired: 20-Sep-2016 12:05 PM EDT
Released: 19-Sep-2016 3:05 PM EDT
University of Alabama at Birmingham |
MedicineChannels:antonio jimeno, University Of Colorado Cancer Center, Head And Neck Cancer, PI3K, Cancer Stem Cells, cancer stem cell |
"After chemo, PI3K helps the cell shut down and weather the storm. Then when the chemo is gone, PI3K helps cancer stem cells start back up again," says University of Colorado Cancer Center investigator, Antonio Jimeno, MD, PhD. |
Embargo expired: 15-Sep-2016 12:00 PM EDT
Released: 14-Sep-2016 2:00 PM EDT
University of Colorado Cancer Center |
MedicineChannels:Biotech, Cell Biology, Stem Cells, Surgery, Transplantation, Nature (journal), Local - Ohio, All Journal News Chimera, Pluripotency, Bioethics, Human Embryonic Stem Cells |
In a World View opinion column published in Nature, a Case Western Reserve University School of Medicine researcher calls for animal-human embryo research to proceed – but only with strong animal protections in place. |
Released: 14-Sep-2016 1:50 PM EDT
Case Western Reserve University |
MedicineScienceChannels:Biotech, Cell Biology, Engineering, Stem Cells, Local - Massachusetts, Local - Boston Metro, All Journal News Stem Cell, Bioenginerring, Neural Stem Cells, Tissue Engineering, hiNSC, Human Brain |
Tufts University researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain, according to a paper published today in Stem Cell Reports. |
Released: 13-Sep-2016 10:05 AM EDT
Tufts University |
MedicineChannels:McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Charles Cox, M.D., Stem Cell Therapy, autologous stem cells, traumatic brain injury (TBI), Department Of Defense |
A research team led by Charles S. Cox, Jr., M.D., at McGovern Medical School at UTHealth has been awarded $6.8 million from the U.S. Department of Defense (DOD) to assess the safety and efficacy of using autologous stem cell therapy in adults with emergent traumatic brain injury. |
Released: 9-Sep-2016 10:05 AM EDT
University of Texas Health Science Center at Houston |
MedicineChannels:All Journal News, Cardiovascular Health, Cell Biology, Kidney Disease, Stem Cells, Featured: MedWire, Staff Picks Stem Cells, Chronic Kidney Disease, atheroscleroisis, Cardiovascular Disease, osteoblasts |
Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease. The research will guide future studies into ways to block minerals from building up inside blood vessels and exacerbating atherosclerosis, the hardening of the arteries. |
Embargo expired: 8-Sep-2016 12:00 PM EDT
Released: 6-Sep-2016 5:05 PM EDT
Washington University in St. Louis |
MedicineChannels:Cancer Research, Leukemia, Stem Cell Transplant, Umbilical Cord Blood Transplant, Cord Blood |
Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine. |
Embargo expired: 7-Sep-2016 5:00 PM EDT
Released: 2-Sep-2016 11:00 AM EDT
Fred Hutchinson Cancer Research Center |
MedicineChannels:Stem Cell, Neurorestoration, Regeneration, Regenerative Medicine, clinicial trials, Neurology, Movement, AST-OPC1, Spinal Cord Injury |
After receiving a stem cell injection into his spine, Kris Boesen, who was paralyzed from his neck to his toes after a car accident, is regaining movement in his extremities and hope for increased independence. |
Embargo expired: 7-Sep-2016 7:30 AM EDT
Released: 6-Sep-2016 6:00 AM EDT
Keck Medicine of USC |
MedicineChannels:Embryology, Chimera, Embryo Donation |
Insoo Hyun has proposed a framework for addressing ethical questions surrounding potentially revolutionary research on part-human, part-animal embryos, which can be produced when human stem cells are transplanted into animal embryos. |
Released: 31-Aug-2016 12:45 PM EDT
Case Western Reserve University |
ScienceChannels:Cirm, California Institute For Regenerative Medicine, Asteroid, Stem Cells, Embryonic Stem Cell, Spinal Cord Injury, Clincal Trial, Dr. Edith Perez, C. Randal Mills, Dr. Randy Mills, Jake Javier |
A clinical trial using stem cells to treat people with recent spinal cord injuries has cleared two key safety hurdles, and been given approval to expand the therapy to a larger group of patients with a much higher dose of cells. |
Released: 31-Aug-2016 12:05 PM EDT
California Institute for Regenerative Medicine (CIRM) |
MedicineChannels:Drug Discovery, Mood Disorder, Schizophrenia, Bipolar Disorder, induced pluripotent stem (iPS) cells |
Sanford Burnham Prebys Medical Discovery Institute (SBP), the Johns Hopkins University School of Medicine, the Salk Institute for Biological Studies, and the University of Michigan will embark on a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced. |
Embargo expired: 31-Aug-2016 9:00 AM EDT
Released: 29-Aug-2016 4:05 PM EDT
Sanford Burnham Prebys Medical Discovery Institute |
MedicineChannels:Cardiovascular Health, Genetics, Heart Disease, Stem Cells, Local - New York, Local - New York Metro Mount Sinai Health System, Icahn School of Medicine at Mount Sinai |
Scientists have created a model of a heart condition called hypertrophic cardiomyopathy (HCM). |
Released: 30-Aug-2016 4:45 PM EDT
Mount Sinai Health System |
MedicineChannels:All Journal News, Local - California, Local - LA Metro, Grant Funded News, Cell Biology, Chemistry, Stem Cells, Featured: DailyWire, Featured: MedWire, Staff Picks tissue-engineered liver, Progenitor Cells |
A research team at Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural components such as hepatocytes, bile ducts and blood vessels. |
Embargo expired: 30-Aug-2016 9:00 AM EDT
Released: 26-Aug-2016 5:05 PM EDT
Childrens Hospital Los Angeles |
MedicineChannels:Cancer, Leukemia, Stem Cells, Hematology, Aging, Secondary Acute Myeloid Leukemia, sAML |
Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer. |
Released: 26-Aug-2016 1:05 PM EDT
University of California San Diego Health Sciences |
MedicineChannels: |
A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment. With further development, this biomaterial could be used to control when immature stem cells differentiate into more specialized cells for regenerative and tissue-engineering-based therapies. |
Released: 26-Aug-2016 8:05 AM EDT
Perelman School of Medicine at the University of Pennsylvania |
MedicineChannels:Cancer, Cell Biology |
SCIENTISTS have demonstrated for the first time the 'perfect storm' of conditions that cells need to start forming cancer, helping to explain why some organs are more susceptible to developing the disease, according to a new study published in Cell today (Thursday). |
Released: 26-Aug-2016 2:05 AM EDT
Cancer Research UK |