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Human Stem Cell Model Reveals Molecular Cues Critical to Neurovascular Unit Formation

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Using human embryonic stem cells, researchers at University of California, San Diego School of Medicine and Moores Cancer Center and Sanford-Burnham Medical Research Institute created a model that allows them to track cellular behavior during the earliest stages of human development in real-time. The model reveals, for the first time, how autonomic neurons and blood vessels come together to form the neurovascular unit.

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Blood to Feeling: McMaster Scientists Turn Blood Into Neural Cells

Stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (brain and spinal cord) neurons as well as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature and itch perception. This means that how a person’s nervous system cells react and respond to stimuli, can be determined from his blood.

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Scientists Discover Origins of the Lymphatic System

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In a first, the Weizmann Institute’s Dr. Karina Yaniv and a team of scientists have determined how the lymphatic system develops in the embryo … and grown lymphatic cells in the lab. Using zebrafish, they showed that the cells originate in a vein niche that harbors angioblasts. Besides solving this century-old puzzle, their work can shed light on disease.

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Brain Cells Capable of “Early-Career” Switch

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Salk scientists find a single molecule that controls the fate of mature sensory neurons

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Master Orchestrator of the Genome Is Discovered, UB Stem Cell Scientists Report

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New research by University at Buffalo scientists finds that genomic regulation may come down to a single growth factor receptor protein.

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Trending Stories Report for 7 May 2015

Trending news releases with the most views in a single day. Topics include: WWII and PTSD, stem cells, cancer, racial segregation, supplements and glaucoma, medical research, cybersecurity, vision research, and physics.

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New Stem Cell May Overcome Hurdles for Regenerative Medicine

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Salk Institute scientists discover new type of stem cell that could potentially generate mature, functional tissues

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The Media is the Message: How Stem Cells Grow Depends On What They Grow Up In

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Writing in the May 4 online issue of the journal Scientific Reports, researchers at University of California, San Diego School of Medicine used a powerful statistical tool called “design of experiments” or DOE to determine the optimal cell culture formula to grow and produce hPSCs.

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Odd Histone Helps Suppress Jumping Genes in Stem Cells, Study Says

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Research begun at Rockefeller University has uncovered a new purpose for a rare type of histone: preventing mutations by keeping certain so-called “jumping genes” in place. This discovery reveals a basic mechanism for epigenetics, or the control of inherited traits through means other than DNA.

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New Method Improves Quality of Stem Cells for Treating Eye Disease

Researchers have developed a new method of purifying stem cells that is faster, more efficient and less expensive than current methods for treating diseases of the retina. The research is being presented at the 2015 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Denver, Colo. The new stem cell purification process involves growing stem cells on a special chip containing a computer system. Each stem cell is monitored closely, and the lower quality cells are removed as soon as they are identified.