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Cal State LA Receives Grant to Develop Future Leaders in the Field of Paper Microfluidics

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Cal State LA has been awarded a grant to educate tomorrow’s leaders in the interdisciplinary field of paper microfluidics. The $375,000 grant from the W.M. Keck Foundation aims to engage more than 1,500 undergraduate students annually in the research of paper microfluidics to contribute to solving real-world scientific problems.

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Study in Mice Suggests Stem Cells Could Ward Off Glaucoma

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An infusion of stem cells could help restore proper drainage for fluid-clogged eyes at risk for glaucoma. That's the upshot of a study led by a Veterans Affairs and University of Iowa team.

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Embryonic Gene Nanog Reverses Aging in Adult Stem Cells

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In a series of experiments at the University at Buffalo, the embryonic stem cell gene Nanog kicked into action dormant cellular processes that are key to preventing weak bones, clogged arteries and other telltale signs of growing old.

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TSRI Scientists Receive Funding to Advance Stem Cell-Based Parkinson’s Therapy

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Scientists at The Scripps Research Institute (TSRI) and Scripps Clinic have received a grant of nearly $2.4 million from the California Institute for Regenerative Medicine (CIRM) to support safety and quality tests of a potential stem cell therapy for Parkinson’s disease.

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Scientists Use Already-Approved Drugs to Force Cancer Cell Death, How to Decide if Watchful Waiting Is the Right Choice, Some Adolescent Cancer Survivors May Require More Comprehensive Mental Health Screening, and MORE in the Cancer News Source

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Cerebrospinal Fluid Signals Control the Behavior of Stem Cells in the Brain

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Prof. Fiona Doetsch's research team at the Biozentrum, University of Basel, has discovered that the choroid plexus, a largely ignored structure in the brain that produces the cerebrospinal fluid, is an important regulator of adult neural stem cells. The study recently published in "Cell Stem Cell" also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavior.

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Study Launched to Determine if Stem Cell Treatment Could Give Patients a Leg Up on Knee Arthritis

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Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis. To evaluate safety and efficacy, investigators are currently recruiting patients with osteoarthritis, which comes from wear and tear on a joint.

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Protein Found to Bolster Growth of Damaged Muscle Tissue

Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

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ALS Research Suggests Stem Cells for Studies Should Be ‘Aged’ to Speed Progress Toward Finding Potential Treatments

Cedars-Sinai scientists are seeking to build an improved stem-cell model of amyotrophic lateral sclerosis (ALS) to accelerate progress toward a cure for the devastating neurological disorder. Their findings demonstrate that current models can be enhanced by the aging of motor neurons to show how ALS damages cells later in life.

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Stem Cells Engineered to Grow Cartilage, Fight Inflammation

With a goal of treating worn, arthritic hips without extensive surgery to replace them, scientists at Washington University School of Medicine in St. Louis have programmed stem cells to grow new cartilage on a 3-D template shaped like the ball of a hip joint. What’s more, using gene therapy, they have activated the new cartilage to release anti-inflammatory molecules to fend off a return of arthritis.

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Defining What It Means to Be a Naive Stem Cell

Whitehead Institute scientists have created a checklist that defines the “naive” state of cultured human embryonic stem cells (ESCs). Such cells provide a better model of early human embryogenesis than conventional ESCs in later stages of development.

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Stem Cell Scientists Discover Genetic Switch to Increase Supply of Stem Cells From Cord Blood for Future Clinical Use

International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increase the supply of stem cells for cancer patients needing transplantation therapy to fight their disease.

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Immunotherapy Benefits Relapsed Stem Cell Transplant Recipients

Dana-Farber Cancer Institute study published in the New England Journal of Medicine suggests that using repeated doses of an immunotherapy drug can restore a complete remission for some relapsed stem cell transplant recipients.

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Breakthrough in Scaling Up Life-Changing Stem Cell Production

Scientists have discovered a new method of creating human stem cells which could solve the big problem of the large-scale production needed to fully realise the potential of these remarkable cells for understanding and treating disease.

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Study Shows New Role for B-Complex Vitamins in Promoting Stem Cell Proliferation

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Folates can stimulate stem cell proliferation independently of their role as vitamins, according to a collaborative study from the University of Georgia and Tufts University, which used an in vitro culture and animal model system in their findings.

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Stem Cell Treatment for Lou Gehrig’s Disease May Be Safe

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, suggests that transplanting human stem cells into the spinal cord may be done safely. The research is published in the June 29, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study was not designed to determine whether the treatment was effective, researchers noted that it did not slow down the progression of the disease.

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New Way Out: Researchers Show How Stem Cells Exit Bloodstream

Researchers have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought. This process, dubbed angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies, but also metastatic cancers.

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Non-Healing Tissue From Diabetic Foot Ulcers Reprogrammed as Pluripotent Stem Cells

Researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts, led by Jonathan Garlick, have established for the first time that skin cells from diabetic foot ulcers can be reprogrammed to acquire properties of embryonic-like cells.

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Mutant Enzyme Study Aids in Understanding of Sirtuin’s Functions

The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of Cornell University researchers has devised a method for isolating one specific enzyme activity to determine its contribution and lead to better overall understanding of SIRT6.

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A New Bio-Ink for 3-D Printing with Stem Cells

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The new stem cell-containing bio ink allows 3D printing of living tissue, known as bio-printing.