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A reporter's PressPass is required to access this story until the embargo expires on 2-May-2016 3:00 PM EDT

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Scientists Turn Back the Clock on Blood Cells, Reprogram Them Into Blood Stem Cells in Mice

Researchers at Boston Children's Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells, which the researchers have dubbed induced HSCs (iHSCs), have the functional hallmarks of HSCs, are able to self-renew like HSCs, and can give rise to all of the cellular components of the blood like HSCs.

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Sanford Health Selected for Global Cell-Therapy Event at Vatican

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Organization recognized for innovative research, care

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Stem Cell Study Finds Mechanism That Controls Skin and Hair Color

A pair of molecular signals controls skin and hair color in mice and humans — and could be targeted by new drugs to treat skin pigment disorders like vitiligo, according to a report by scientists at NYU Langone Medical Center.

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Cell Transplant Treats Parkinson's in Mice Under Control of Designer Drug

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A University of Wisconsin-Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell. The cells in question are neurons and make the neurotransmitter dopamine, whose deficiency is the culprit in the widespread movement disorder Parkinson's disease.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 3-May-2016 7:45 PM EDT

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Media Invitation: Press Conference by Webcast

This ARVO Meeting showcases cutting-edge eye and vision science and an early glimpse into the latest advances in potential treatments for eye disease and blindness — often years ahead of their introduction to the clinic.

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Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source

Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source

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McMaster Scientists Uncover New Way to Grow Rare Life-Saving Blood Stem Cells

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Discovery provides a serious advantage in determining how to maximize blood stem cells in therapeutics and could help ease current stem cell shortages.

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Confused Cells Lead to Genetic Disorders Like Heart Problems, Premature Aging

It has been disorienting to the scientific and medical community as to why different subtle changes in a protein-coding gene causes many different genetic disorders in different patients -- including premature aging, nerve problems, heart problems and muscle problems. no other gene works like this. According to a new study, co-authored by Binghamton University faculty Eric Hoffman, it has to do with cell “commitment.”

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NYU Langone's Laura and Isaac Perlmutter Cancer Center and Technion-Israel Institute of Technology Launch Global Research Initiative

Drug-carrying “nanoghosts” that battle melanoma and new treatments for malignant mesothelioma will be the focus of the first joint research projects led by NYU Langone Medical Center and the Technion-Israel Institute of Technology under a groundbreaking research initiative.

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Scientist Models Developmental Disorder in Adult Stem Cells

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Dr. Kevin Francis’ research appears in Nature Medicine

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Fashion Design Meets U-M Research in Wearable Human Stem Cell Images

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A noted designer of artistic ties has turned scientific images into a striking design that can be worn by men and women - and the proceeds will aid bipolar disorder research.

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Preliminary Study: Antibody Therapy Reduces Cancer Stem Cells in Multiple Myeloma

An experimental antibody treatment decreased by half the number of cancer stem cells that drive the growth of tumors in nearly all patients with multiple myeloma, a cancer of the bone marrow and bone tissue, according to results of a preliminary clinical trial led by Johns Hopkins Kimmel Cancer Center scientists.

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UCI Study Finds Safer Stem Cell-Derived Therapy for Brain Radiation Recovery

While stem cells have shown promise for treating brain regions damaged by cancer radiation treatments, University of California, Irvine researchers have found that microscopic vesicles isolated from these cells provide similar benefits without some of the risks associated with stem cells.

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Heart Failure Patients Experience Improved Outcomes Following Investigational Stem Cell Treatment

An investigational stem cell therapy derived from patients’ own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.

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Cell Therapy May Mend Damaged Hearts, Study Says

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End-stage heart failure patients treated with stem cells harvested from their own bone marrow experienced 37 percent fewer cardiac events - including deaths and heart failure hospital admissions - than a placebo-controlled group, according to a new study. Results from ixCELL-DCM, the largest cell therapy clinical trial for treating heart failure to date, will be presented at the 2016 American College of Cardiology annual meeting and published online in The Lancet on April 4.

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New Study Finds that Despite More Women in Science, We Still Perceive Women to be Incompatible with STEM Fields

Linda Carli's "Stereotypes About Gender and Science: Women ≠ Science” shows that despite significant progress made, women are still thought to lack the qualities needed to be successful scientists, and the findings suggest this may contribute to discrimination and prejudice against women in those fields.

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Stem Cells Used to Successfully Regenerate Damage in Corticospinal Injury

Writing in Nature Medicine, researchers at University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System, with colleagues in Japan and Wisconsin, report that they have successfully directed stem cell-derived neurons to regenerate lost tissue in damaged corticospinal tracts of rats, resulting in functional benefit.

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How Cancer Stem Cells Thrive When Oxygen Is Scarce

Working with human breast cancer cells and mice, scientists say new experiments explain how certain cancer stem cells thrive in low oxygen conditions. Proliferation of such cells, which tend to resist chemotherapy and help tumors spread, are considered a major roadblock to successful cancer treatment.