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Researchers Succeed in Programming Blood Forming Stem Cells

Study is first step towards generating patient-specific blood products for cell-replacement therapy.

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Fingernails Reveal Clues to Limb Regeneration

Mammals possess the remarkable ability to regenerate a lost fingertip, including the nail, nerves and even bone. In humans, an amputated fingertip can sprout back in as little as two months, a phenomenon that has remained poorly understood until now. In a paper published today in the journal Nature, researchers at NYU Langone Medical Center shed light on this rare regenerative power in mammals, using genetically engineered mice to document for the first time the biochemical chain of events that unfolds in the wake of a fingertip amputation. The findings hold promise for amputees who may one day be able to benefit from therapies that help the body regenerate lost limbs.

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Researchers Discover A New Liver Cell that Shows Promise for Cellular Therapy for Liver Regeneration

New research from the Icahn School of Medicine at Mount Sinai, published in the journal Cell Stem Cell today, suggests that it may one day become possible to regenerate a liver using cell therapy in patients with liver disease. Investigators discovered that a human embryonic stem cell can be differentiated into a previously unknown liver progenitor cell, an early offspring of a stem cell, and produce mature and functional liver cells.

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Wolbachia Bacteria Evolved to Infect Stem Cell Niches Through Successive Generations of Their Hosts

A new study by Boston University researchers provides evidence that Wolbachia target the ovarian stem cell niches of its hosts—a strategy previously overlooked to explain how Wolbachia thrive in nature.

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UCLA Scientists Isolate and Characterize New Population of Stress-Resistant Pluripotent Stem Cells in Fat Tissue Removed During Liposuction

Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells easily derived from fat tissue that are able to differentiate into virtually every cell type in the human body without genetic modification.

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Adult Stem Cells Could Hold Key to Cure Type 1 Diabetes

A University of Missouri scientist has discovered that by combining cells from bone marrow with a new drug may help cure type 1 diabetes. The discovery is reported in the current online issue of Diabetes.

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Study Shows Significantly Improved Survival Rates for Stem Cell Transplant Recipients

Study of 38,000 blood stem cell transplant recipients, led by Dr. Theresa Hahn of Roswell Park Cancer Institute, shows that survival rates increased significantly over 12 years, and numbers of patients receiving transplants grew dramatically.

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Engineered Stem Cell Advance Points Toward Treatment for ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

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Down Syndrome Neurons Grown From Stem Cells Show Signature Problems

In new research published this week, Anita Bhattacharyya, a neuroscientist at the Waisman Center at the University of Wisconsin-Madison, reports on brain cells that were grown from skin cells of individuals with Down syndrome.

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