The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.
Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
One of the most invasive Australian weeds is being touted as a potential economic crop, with benefits for the construction, mining and forestry industries, and potentially many First Nations communities.
Dustin Tyler, the Kent H. Smith II Professor of Biomedical Engineering at CWRU’s Case School of Engineering, co-founded a company that restores for people the sensation of touch—with help from a set of electrical rings that fit snugly on users’ fingers—from a distance.
The qualities of flowing blood, or hemodynamics, hold important insights into vascular diseases, but technological limitations have largely kept measurements of these properties out of reach in the clinic. Now, there may be a potential solution on the horizon.
Columbia Biomedical Engineer Ke Cheng has developed a technique that uses inhalation of exosomes, or nanobubbles, to directly deliver IL-12 mRNA to the lungs of mice.
In a study involving nearly 1,000 patients seen at the Baltimore Convention Center Field Hospital (BCCFH) during a five-month period in 2022 — researchers at Johns Hopkins Medicine, the University of Maryland School of Medicine and five other collaborators report that a rapid antigen test (RAT) for detecting SARS-CoV-2, the virus that causes COVID-19, can be used at home with accuracy comparable to the same test being administered by a health care professional.
Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson's disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.
Over 100,000 individuals in the United States are currently in need of organ transplants. The demand for organs, such as hearts, kidneys, and livers, far exceeds the available supply and people sometimes wait years to receive a donated organ.
Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections. The findings were described in the February 6 online issue of Nature Structural & Molecular Biology.
Over the past two decades, microfluidic devices, which use technology to produce micrometer-sized droplets, have become crucial to various applications.
Northwest Biotherapeutics (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, announced today that the key development work for the Flaskworks manufacturing system has been completed and an external vendor has been engaged to produce GMP-grade units of the system.
Beckman researchers and collaborators received $3 million from the U.S. National Institute on Aging to develop diagnostic tools and imaging agents for the early detection of Alzheimer’s disease.
An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.
Madison Wisconsin based Imbed Biosciences, Inc has been awarded a Technology Breakthrough designation for PelashieldAM™ with Premier, Inc. through its Kiindo™ pediatric performance group and collaborative.
The Federation of American Societies for Experimental Biology (FASEB), the largest coalition of biomedical research associations in the United States, announces a collaboration between FASEB Publications and Dryad.
University at Albany scientist Scott Tenenbaum, founder of UAlbany spinoff company sxRNA Technologies, Inc. (sxRNA Tech), has received $500,000 from the National Institute on Aging, part of the National Institutes of Health, to study how aging brain cells shape the progression of Alzheimer’s disease, and advance RNA technology that could inform new therapeutics to prevent and treat Alzheimer's and related dementias.
The Environmental Molecular Sciences Laboratory is hosting a free webinar at noon PST on Feb. 7 to detail available metabolomics technologies that the scientific community can access for studying biological systems.
الأورام الدبقية عالية الدرجة هي أورام سرطانية تنتشر بسرعة في الدماغ أو الحبل النخاعي. في دراسة جديدة أجريت تحت إشراف مايو كلينك، وجد الباحثون أن هوامش أورام الدماغ الغزوية للورم الدبقي عالي الدرجة تحتوي على تغيرات جينية وجزيئية مميزة بيولوجيًا تشير إلى السلوك العدواني وتكرار المرض. وتُظهر النتائج تصورات متعمقة للعلاجات المحتملة التي يمكن أن تحوّل مسار المرض.
Russian scientists from The Federal Research Centre “Fundamentals of Biotechnology” of the Russian Academy of Sciences (Research Center of Biotechnology RAS) tested a new potential antidepressant on rodents.
The Federation of American Societies for Experimental Biology (FASEB) and the Office of Data Science Strategy at the National Institutes of Health (NIH) announced today the recipients of this year’s FASEB DataWorks! Prize.
BACKGROUNDPeripheral nerve injury can result in significant clinical complications that have uncertain prognoses. Currently, there is a lack of effective pharmacological interventions for nerve damage, despite the existence of several small
Mesenchymal stromal/stem cells (MSCs) have garnered significant attention in the field of regenerative medicine due to their remarkable therapeutic potential. MSCs play a pivotal role in maintaining tissue homeostasis and possess diverse fu
BACKGROUNDStem cell therapy has shown great potential for treating diabetic foot (DF). AIMTo conduct a bibliometric analysis of studies on the use of stem cell therapy for DF over the past two decades, with the aim of depicting the current
The incidence of premature ovarian insufficiency (POI) is increasing worldwide, particularly among younger women, posing a significant challenge to fertility. In addition to menopausal symptoms, POI leads to several complications that profo
JMIR Publications is pleased to announce a new theme issue titled “Machine Learning-Based Predictive Models Using Genomic Data” in JMIR Bioinformatics and Biotechnology.
The Association for Research in Vision and Ophthalmology (ARVO) Foundation congratulates Neil Lagali, PhD (Linköping University, Sweden) and Mehrdad Rafat, PhD (LinkoCare Life Sciences AB /NaturaLens AB, Sweden) — recipients of the 2023 Point of View Award.
New biomarkers with improved diagnostic performance for early detection of lupus nephritis have been discovered in the University of Houston lab of Chandra Mohan, a pioneer in lupus research.
Cedars-Sinai Cancer investigators have used a unique precision medicine and artificial intelligence (AI) tool called the Molecular Twin Precision Oncology Platform to identify biomarkers that outperform the standard test for predicting pancreatic cancer survival.
A simple way to find out whether a gilt is already pregnant is through the Progesterone Test Kit – an innovation developed by Chulalongkorn University researchers that is easy for farmers to use, with fast and accurate results.
A Philadelphia College of Osteopathic Medicine faculty member who specializes in basic and translational science research for spinal bulbar and muscular atrophy (SBMA), also known as Kennedy's disease, is propelling efforts to model and identify therapeutic targets for this neuromuscular disease with two new grants.
Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other organelles generate energy, assemble new molecules and transport cargo. At Sanford Burnham Prebys, Feng will use cryo-EM to reveal new ways to stop or prevent cancers.
By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.
New study by Hebrew University reveals that a significant proportion (over one fifth) of human pluripotent stem cell samples that can be used in regenerative medicine possess cancer-related mutations, with the majority acquired during their propagation in culture.
The AccuSignal™ Nuclease ELISA Kit is designed to detect any Serratia marcescens endonuclease, such as Benzonase®, DENARASE®, and Turbonuclease, to evaluate manufacturing processes for biological therapeutics, gene therapy vectors, vaccine preparations, and more.
Rice University scientists have developed a noninvasive way to monitor gene expression dynamics in the brain, making it easier to investigate brain development, cognitive function and neurological diseases, according to a study published in Nature Biotechnology.
RUDN University biologist described a green method for obtaining copper oxide nanoparticles from the noni plant (Morinda citrifolia), common in Asia. These nanoparticles have pronounced bactericidal and fungicidal properties.
Mycelial fibers, the fibrous cells found in fruiting mushroom bodies, have gained momentum as a sustainable material for making leather and packaging owing to their excellent formability.
A new RADx Tech fellowship aims to increase diversity among biotechnology innovators. Fellows who recently completed the six-month program share their perspectives on how the fellowship helped them advance their technologies.