Curated News: Medical Meetings

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Released: 22-Jun-2014 5:00 PM EDT
Gestational Diabetes is Associated with Declining Cognitive Function
Endocrine Society

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey. The results were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 5:00 PM EDT
Cold Exposure Stimulates Beneficial Brown Fat Growth
Endocrine Society

Long-term mild cold exposure can stimulate brown fat growth and activity in humans and may benefit glucose and energy metabolism, a new study finds. The results were presented in a poster Sunday, June 22 at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

Released: 22-Jun-2014 4:00 PM EDT
ICE/ENDO 2014 Sets Record for Largest-Ever Annual Meeting of the Endocrine Society
Endocrine Society

ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society, has tallied more registrants than any other annual meeting in the Endocrine Society’s nearly 100-year history.

Released: 22-Jun-2014 4:00 PM EDT
Denosumab Treatment for Postmenopausal Osteoporosis Increases Bone Density
Endocrine Society

Postmenopausal women with osteoporosis who take denosumab long-term have increased bone density, sustained low rate of fractures, and a favorable benefit/risk profile, a new multinational study finds. The results were presented Sunday, June 22, at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

Released: 22-Jun-2014 2:45 PM EDT
BPA Exposure During Fetal Development Raises Risk of Precancerous Prostate Lesions Later in Life
Endocrine Society

A new study has found for the first time that the endocrine-disrupting chemical bisphenol A (BPA) reprograms the developing prostate, making the gland more susceptible to precancerous lesions and other diseases later in a man’s life. The results will be reported Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 2:00 PM EDT
Hypothyroidism May Lead to Impaired Driving
Endocrine Society

People with significant hypothyroidism can experience impaired driving similar to those who are driving when intoxicated by alcohol, a new study finds. The results were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 2:00 PM EDT
High Blood Sugar Causes Brain Changes that Raise Depression Risk
Endocrine Society

Researchers have found a possible biological reason why people with diabetes are prone to depression. A new study shows that high blood glucose (sugar) levels in patients with Type 1 diabetes increase the levels of a brain neurotransmitter associated with depression, and alter the connections between regions of the brain that control emotions. The results will be presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 2:00 PM EDT
Soy Supplements Appear to be Safe, Beneficial in Diabetic Men
Endocrine Society

Soy protein supplements, which contain natural estrogens, do not reduce testosterone levels in men with Type 2 diabetes who already have borderline-low testosterone, according to a new study. The results were presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 2:00 PM EDT
Most People with Type 1 Diabetes Do Not Use Diabetes Devices to Get Long-term Data
Endocrine Society

Almost 70 percent of adults with Type 1 diabetes never use their blood glucose self-monitoring devices or insulin pumps to download historical data about their blood sugar levels and insulin doses—information that likely would help them manage their disease better. These new survey results, which were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago, also show that only 12 percent of patients regularly review their past glucose and insulin pump data at home.

Released: 22-Jun-2014 1:35 PM EDT
Growth Hormone Defect May Protect against Diabetes, Cancer in Unique Ecuador Population
Endocrine Society

Growth Hormone Defect May Protect against Diabetes, Cancer in Unique Ecuador Population

Released: 22-Jun-2014 12:55 PM EDT
Low Number of Taste Buds Linked to Older Age, Higher Fasting Blood Sugar
Endocrine Society

A study finds that the number of taste buds we have on our tongue decreases as we get older, and that the lower the number of taste buds, the more likely for fasting blood glucose (sugar) levels to be higher than normal. The results will be presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 22-Jun-2014 12:00 PM EDT
Vitamin D Can Lower Weight, Blood Sugar via the Brain
Endocrine Society

Vitamin D treatment acts in the brain to improve weight and blood glucose (sugar) control in obese rats, according to a new study being presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 5:00 PM EDT
Veterans with Blast Traumatic Brain Injury May Have Unrecognized Pituitary Dysfunction
Endocrine Society

In soldiers who survive traumatic brain injury from blast exposure, pituitary dysfunction after their blast injury may be an important, under-recognized, and potentially treatable source of their symptoms, a new study finds. The results were presented Saturday, June 21 at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

Released: 21-Jun-2014 5:00 PM EDT
Polycystic Ovary Syndrome Tied to Increased Risk of Type 2 Diabetes, Independent of Body Mass Index
Endocrine Society

Women with polycystic ovary syndrome are at increased risk for type 2 diabetes mellitus (T2DM), and this risk appears to be independent of body mass index (BMI), a new study finds. The results were presented Saturday at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

Released: 21-Jun-2014 4:00 PM EDT
Possible New Weapon Found for Fighting Some Types of Breast Cancer
Endocrine Society

Researchers believe they have discovered one reason why some women with estrogen receptor-positive breast cancer may respond poorly or only temporarily to estrogen-blocking drugs such as tamoxifen. Results of a new study, which was presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago, point to a previously unrecognized role of the androgen receptor.

Released: 21-Jun-2014 3:00 PM EDT
Diabetes Drug Appears to Work for Weight Management, Reversing Prediabetes
Endocrine Society

Nondiabetic obese and overweight people lose more weight, are more likely to reverse prediabetes and are slower to develop type 2 diabetes when they take the diabetes drug liraglutide in addition to dieting and exercising, a new study finds. The results of the multicenter study were presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 2:00 PM EDT
Raising Low Vitamin D Levels Lowers Risk of Prediabetes Progressing to Diabetes
Endocrine Society

Vitamin D and calcium supplementation along with diet and exercise may prevent Type 2 diabetes in prediabetic individuals who have insufficient vitamin D in their bodies, a study from India suggests. The results were presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 2:00 PM EDT
Gender-based Treatment Needed for Cardiovascular Risk Factors in Diabetes
Endocrine Society

Women with Type 2 diabetes and high cholesterol are less likely than their male peers to reach treatment goals to lower their “bad” cholesterol, or low-density lipoprotein (LDL) cholesterol, despite access to cholesterol-lowering medication, a Canadian study finds. The results were presented on Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 1:00 PM EDT
Dietary, Lifestyle Changes Made Early in Pregnancy Benefit Obese Women
Endocrine Society

Obese pregnant women who adhere to an intensive nutritional and exercise program starting in the first trimester gain less weight in pregnancy and have fewer pregnancy complications compared with peers who receive standard prenatal care, a new study from China finds. The results were presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 1:00 PM EDT
Fatty Liver is Linked to Maternal Use of the SSRI Antidepressant Fluoxetine
Endocrine Society

Adult offspring of mothers who used fluoxetine, a common antidepressant, during pregnancy were more likely to develop a fatty liver, a new animal study has found. The results will be reported Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

Released: 21-Jun-2014 12:25 PM EDT
Blood Kisspeptin Level Test May Identify which Pregnant Women are at High Risk for Miscarriage
Endocrine Society

Measuring pregnant women's blood kisspeptin levels early in their pregnancy may effectively predict their risk of miscarriage, a new study finds. The results will be presented Saturday at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society in Chicago.

19-Jun-2014 11:00 AM EDT
Antidepressant Use During Pregnancy May Lead to Childhood Obesity and Diabetes
McMaster University

Researchers have demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver of the adult offspring, raising new concerns about the long-term metabolic complications in children born to women who take SSRI antidepressants during pregnancy.

Released: 16-Jun-2014 12:00 PM EDT
Vitamin A Derivative Potentially Treats Type 2 Diabetes and Prevents Its Cardiovascular Complications
Universite de Montreal

Researchers at the University of Montreal and CHUM Research Centre (CRCHUM) recently demonstrated the potential of retinoic acid (RA), a derivative of Vitamin A, in treating obesity and type 2 diabetes and preventing their cardiovascular complications.

Released: 13-Jun-2014 4:00 PM EDT
Media Advisory - June 14-15: Artificial Pancreas Findings Presented by UVA Health System Researchers
University of Virginia Health System

Researchers from the University of Virginia Center for Diabetes Technology are presenting their findings from artificial pancreas clinical trials at the American Diabetes Association’s 74th Scientific Sessions in San Francisco on June 14-15.

Released: 11-Jun-2014 9:15 AM EDT
ICE/ENDO 2014 News Conference and Webcast Schedule
Endocrine Society

The latest research discoveries on diabetes, weight loss, endocrine-disrupting chemicals, obesity and pregnancy hormones will be highlighted in a series of press conferences at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society.

4-Jun-2014 10:00 AM EDT
International Team Creates Heart Disease Risk Tool Tailored to Rheumatoid Arthritis Patients
Mayo Clinic

Rheumatoid arthritis patients overall are twice as likely as the average person to develop heart problems. Pinpointing which rheumatoid arthritis patients need stepped-up heart disease prevention efforts has been a challenge; research by Mayo Clinic and others has found that standard heart disease risk assessment tools may underrate the danger a particular person faces. To better pinpoint rheumatoid arthritis patients’ heart disease risk, an international team that includes Mayo researchers has created a heart disease risk calculator tailored to rheumatoid arthritis.

Released: 10-Jun-2014 8:00 AM EDT
Value of Breast Cancer Molecular Subtyping Documented by Independent Study Comparing Genomic Tests at ASCO 2014
Agendia

There are substantial differences between the results provided by Agendia’s breast cancer genomic tests and more limited results from the 21-gene assay, according to findings presented at the recently concluded ASCO meeting.

Released: 9-Jun-2014 12:00 PM EDT
Einstein & Montefiore Investigators Present Research at American Diabetes Association Scientific Sessions
Montefiore Health System

Einstein-Montefiore scientists and clinicians are participating in nearly three dozen presentations, sessions and symposia during the five-day meeting. They will address a range of basic, translational and clinical research topics—from medication adherence in adolescents and the impact on resveratrol and vitamin D on insulin resistance to epigenetic and genetic triggers for the disease.

Released: 9-Jun-2014 8:00 AM EDT
African-American Women More Likely to Be Diagnosed with Higher Risk Breast Cancer
MedStar Washington Hospital Center

A research study led by cancer specialists at MedStar Washington Hospital Center found that African-American women frequently present with biologically less favorable subtypes of breast cancer.

4-Jun-2014 1:55 PM EDT
Loyola Successfully Reduces Central Line Bloodstream Infections
Loyola Medicine

Loyola University Medical Center achieved a 68 percent decrease in the overall number of central line-associated bloodstream infections (CLABSI) over a 12-month period. A two-year study compared the use of disinfection caps to an intense scrub-the-hub intervention to standard care. Scrub-the-hub refers to cleaning catheter connector hubs and injection ports with alcohol for the recommended 15 seconds before accessing the central line, a catheter placed in a large vein to deliver medicine and liquids during hospitalization.

Released: 4-Jun-2014 12:00 PM EDT
Early Palliative Support Services Help Those Caring for Patients with Advanced Cancer
Norris Cotton Cancer Center Dartmouth-Hitchcock Medical Center

Dartmouth researchers have found that those caring for patients with advanced cancer experienced reduced depression and felt less burdened by caregiving tasks when palliative support services were offered soon after the patient’s diagnosis. They presented their findings at the American Society of Clinical Oncologist (ASCO) annual meeting in Chicago on June 3, 2014.

Released: 3-Jun-2014 6:00 PM EDT
Are Your Pets Disturbing Your Sleep? You’re Not Alone, Mayo Clinic Study Finds
Mayo Clinic

While countless pet owners peacefully sleep with a warm pet nearby, a new Mayo Clinic study, presented this week at the 29th Annual Meeting of the Associated Professional Sleep Societies, finds an increase in the number of people experiencing sleep disturbances because of their pets.

Released: 3-Jun-2014 4:00 PM EDT
Early, Phone-Based, Palliative Care Support Improves Caregiver Quality of Life and Patient Survival
University of Alabama at Birmingham

UAB School of Nursing federally funded study shows both the patient and caregiver benefit from early palliative care.

30-May-2014 4:00 PM EDT
Stopping Statins May Benefit Terminally Ill Patients
University of Colorado Cancer Center

Results presented today at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) and June 6 at the European Association of Palliative Care Research Conference show that stopping statins for cholesterol management in the late stages of cancer or other terminal illnesses may offer quality-of-life and even life-extending benefits.

30-May-2014 4:00 PM EDT
Tumor Responses with Crizotinib in MET-Amplified Disease Help Define a New Targetable Form of Lung Cancer
University of Colorado Cancer Center

A study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2014 reports the results of a first-in-human, phase 1 dose escalation trial of crizotinib (XALKORI) in 14 patients with advanced, MET-amplified non-small cell lung cancer (NCT00585195).

Released: 2-Jun-2014 1:00 PM EDT
Penn Medicine Researchers Investigate Worry and Behavior Among Teens at Higher Risk for Breast Cancer
Perelman School of Medicine at the University of Pennsylvania

Teenage girls with a familial or genetic risk for breast cancer worry more about getting the disease, even when their mother has no history, compared to girls their age with no known high risks, according to new data presented today by researchers from Penn Medicine’s Abramson Cancer Center at the annual meeting of the American Society of Clinical Oncology in Chicago.

Released: 2-Jun-2014 10:30 AM EDT
New Therapies Harness Power of the Immune System Against Cancer
American Society of Clinical Oncology (ASCO)

CHICAGO – New research on innovative immunotherapies for advanced or high-risk melanoma and cervical cancer were presented today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). These treatments – used alone or in combination – fight cancer by activating and amplifying the body’s immune response to the disease.

30-May-2014 4:00 PM EDT
Study Shows Tale of Two Prognoses in Pediatric Brain Tumor, Pilocytic Astrocytoma
University of Colorado Cancer Center

Research presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2014 used a newly designed test for K:B fusion to show that point mutations lead to a more dangerous form of the disease than does K:B fusion.

30-May-2014 11:00 AM EDT
Ovarian Cancer Subtypes May Predict Response to Bevacizumab
Mayo Clinic

Molecular sequencing could identify ovarian cancer patients who are most likely to benefit from treatment with bevacizumab (Avastin), a Mayo Clinic-led study has found. Results of the research were presented today at the 2014 American Society of Clinical Oncology Annual Meeting.

Released: 1-Jun-2014 10:25 AM EDT
Major Advances in Breast, Prostate and Colorectal Cancer Treatment Featured at ASCO’s Annual Meeting
American Society of Clinical Oncology (ASCO)

Findings from four phase III clinical trials in breast, prostate, and colorectal cancers were released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies were presented in ASCO’s Plenary session, which features the meeting’s most important clinical cancer research with the greatest potential to impact patient care.

29-May-2014 3:00 PM EDT
Chemotherapy Following Radiation Treatment Improves Progression-Free Survival and Overall Survival in Adults with Low-Grade Brain Cancer
Mayo Clinic

CHICAGO — A chemotherapy regimen consisting of procarbazine, CCNU, and vincristine (PCV) administered following radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas, a form of brain cancer, when compared to radiation therapy alone. The findings were part of the results of a Phase III clinical trial presented today at the 2014 American Society of Clinical Oncology Annual Meeting by the study’s primary author Jan Buckner, M.D., deputy director, Cancer Practice, at Mayo Clinic Cancer Center.

Released: 1-Jun-2014 7:30 AM EDT
ALTTO Test of Dual HER2 Blockade Finds Single Agent — Trastuzumab — Remains the Gold Standard
Mayo Clinic

CHICAGO — June 2, 2014 — In the largest clinical trial testing the effectiveness of one versus two drugs to treat HER2-positive breast cancer, lapatinib (Tykerb) did not add benefit to the standard trastuzumab (Herceptin) adjuvant therapy, researchers report at the 50th annual meeting of the American Society of Clinical Oncology (ASCO).

Released: 1-Jun-2014 7:30 AM EDT
Drug Combination Extends Survival by More Than a Year in Metastatic Prostate Cancer
Dana-Farber Cancer Institute

Men with newly diagnosed metastatic, hormone-sensitive prostate cancer lived more than a year longer when they received a chemotherapy drug as initial treatment instead of waiting to for the disease to become resistant to hormone-blockers, report scientists from Dana-Farber Cancer Institute and the Eastern Co-operative Oncology Group.

Released: 31-May-2014 4:00 PM EDT
Clinical Trial Analysis Suggests Drug Combination May Be Highly Effective in Recurrent Ovarian Cancer
Dana-Farber Cancer Institute

Significant improvement with the use of a combination drug therapy for recurrent ovarian cancer was reported at the annual meeting of the American Society of Clinical Oncology (ASCO) meeting in Chicago.

30-May-2014 4:00 PM EDT
Results in Phase I Trial of OMP-54F28, a Wnt Inhibitor Targeting Cancer Stem Cells
University of Colorado Cancer Center

At the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO), University of Colorado Cancer Center researchers reported results of a Phase I trial of OMP-54F28 (FZD8-Fc), an investigational drug candidate discovered by OncoMed Pharmaceuticals targeting cancer stem cells (CSCs).

Released: 31-May-2014 1:00 PM EDT
Studies Reveal New Strategies to Improve Quality of Life for Patients, Survivors and Caregivers
American Society of Clinical Oncology (ASCO)

Key studies released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) identify new strategies for easing the short- and long-term effects of cancer therapy and improving the quality of life of patients with cancer, as well as their caregivers.

30-May-2014 4:00 PM EDT
ALK, ROS1 and now NTRK1: Study Shows Prevalence of New Genetic Driver in Lung Cancer
University of Colorado Cancer Center

A University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) draws a line from mutation of the gene NTRK1, to its role as an oncogene in non-small cell lung cancer, to treatment that targets this mutation.

Released: 30-May-2014 4:50 PM EDT
Results of Phase I Study of DMOT4039A, an Antibody-Drug Conjugate, in Patients with Pancreatic or Ovarian Cancer
University of Colorado Cancer Center

A study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) describes the results of a phase I clinical trial of the investigational agent DMOT4039A against pancreatic and ovarian cancers. In this early clinical trial with the goal of identifying possible risks and defining likely dosages, the drug was well tolerated and in some patients showed initial evidence of anti-cancer activity.

Released: 30-May-2014 2:20 PM EDT
New Test Increases Sensitivity of HPV Detection in Cancer
Sanford Health

Cancer panel reveals new insights in HPV cancers.

27-May-2014 10:35 AM EDT
New Drug Treatment Helps Prevent Early Menopause in Breast Cancer Patients
Loyola Medicine

Among young breast cancer patients, one of the most distressing side effects of chemotherapy is early menopause. But a major study finds the risk of early menopause can be significantly reduced by adding the drug goserelin to the chemotherapy regimen.



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