Scientists from the Florida campus of The Scripps Research Institute have established conclusively that an activating protein, called “Rhes,” plays a pivotal role in focusing the toxicity of Huntington’s disease.
Chemists at The Scripps Research Institute have invented the first practical, scalable method for synthesizing jiadifenolide, a plant-derived molecule that may have powerful brain-protecting properties.
Cedars-Sinai's medical tip sheet for June includes story ideas about how memories and memory-based decisions are processed in the brain, getting a second opinion via a tele-consult, and more.
The UCLA Medical Group has again earned the highest rating possible in an annual survey conducted by CAPG, an association representing physician organizations in 38 states, Washington, D.C., and Puerto Rico. UCLA earned five stars in the report, which assesses health care systems’ tools for delivering better patient experience and better population health, as well as overall affordability.
Scientists from the Florida campus of The Scripps Research Institute have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming cells in patients suffering from bone loss.
Enhancing education through technology is a passion of Jeff Elman’s. “My first job after college was as a high school teacher in an area of Boston where few kids went to college,” said the UC San Diego professor of cognitive science and former dean of the Division of Social Sciences. “My love for teaching and learning has continued ever since. But over the years, I’ve become increasingly aware that there’s often a mismatch between what we know from the science of learning and the way we actually teach. Online platforms and the use of technology are not silver bullets—after all, they can be misused—but they do open up exciting new educational possibilities.”
A new study from The Scripps Research Institute, Florida campus, integrates neuroscience and psychological research to reveal how sleep suppresses certain nerve cell activity that promotes forgetting, insuring that at least some memories will last.
While it is well-known that weight gain results from an imbalance between what we eat and our energy expenditure, not so obvious is the role the nervous system plays in controlling energy balance. Scientists from the Florida campus of The Scripps Research Institute have shed light on the question.
X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory have for the first time observed an exotic property that could warp the electronic structure of a material in a way that reduces heat buildup and improves performance in ever-smaller computer components.
Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety and efficacy of an unprecedented drug therapy for autism.
Researchers at Children’s Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).
Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors. The researchers believe the finding, published June 10 by EBioMedicine, could prompt an immediate review of the current standard of care for patients with certain so-called “superbug” infections.
Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.1 million from the National Institute of Neurological Disorders and Stroke to study a protein that has been closely linked in animal models to Parkinson’s disease and Huntington’s disease.
On Friday, May 22, an 18-member team of physicians and nurses from Children's Hospital Los Angeles (CHLA) and Keck Medicine of the University of Southern California (USC) led an international collaboration to separate a pair of six-month-old conjoined Haitian twins, the first such operation ever performed on Haitian soil. James Stein, associate chief of surgery at Children's Hospital, was lead surgeon during the rare medical procedure.
U.S. News and World Report has recognized Mattel Children’s Hospital UCLA for excellence in nine specialties in the 2015-16 Best Children’s Hospitals rankings.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain and the depression, anxiety and substance abuse seen in more than half of these patients, UC Irvine and UCLA researchers report.
Using functional magnetic resonance imaging, a team of UCLA researchers has shown for the first time that children with autism spectrum disorder (ASD) who are overly sensitive to sensory stimuli have brains that react differently than those with the disorder who don’t respond so severely to noises, visual stimulation and physical contact.
Ongoing webinars from the American Association of Critical-Care Nurses have quickly proven to be an effective tool for moving new findings and evidence-based recommendations into nursing practice at the bedside.
On Friday, May 22, an 18-member team of physicians and nurses from Children's Hospital Los Angeles (CHLA) and Keck Medicine of the University of Southern California (USC) led an international collaboration to separate a pair of six-month-old conjoined Haitian twins, the first such operation ever performed on Haitian soil.
Ranked No. 1 in California and among the top 10 nationally, CHLA is once again named to the prestigious Honor Roll in the U.S. News & World Report survey of the nation’s best children’s hospitals.
The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury’s verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. Cedars-Sinai researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are processed. They show that the activity of these neurons is indicative of the confidence by which a memory will be retrieved.
Claudio Pellegrini, a visiting scientist and consulting professor at the Department of Energy’s SLAC National Accelerator Laboratory and distinguished professor emeritus at the University of California, Los Angeles, will receive the 2014 Enrico Fermi Award for his role in laying the scientific groundwork for the X-ray free-electron laser.
Berkeley Lab scientist Sebastien Biraud and Margaret Torn are leading an aerial campaign for DOE’s Atmospheric Measurement Research (ARM) Climate Research Facility over Alaska’s North Slope to take air samples and find out why current climate models underestimate how rapidly the Arctic is getting warmer.
The Sanford Consortium for Regenerative Medicine in La Jolla, California, and the Takeda Pharmaceutical Company Limited (Takeda) have agreed to establish a $10-million, five-year Innovation Alliance that would advance each organization’s research missions.
Scientists from the Florida campus of The Scripps Research Institute have found that a drug candidate with anticancer potential can be activated by one of the body’s natural responses to cellular stress. Once activated, the agent can kill prostate cancer cells.
Researchers at University of California, San Diego School of Medicine and University College Dublin (UCD) have found that augmenting a naturally occurring molecule in the body can help protect against obesity-related diseases by reducing inflammation in the fat tissues.
Scientists at The Scripps Research Institute have found that state-specific odor “blindness” exists in female mice, who cannot sense the odor of male mice when in diestrus, the period of sexual inactivity during the reproductive cycle, pointing to new avenues for studying senses and behavior.
In a scientific discovery that has significant implications for preventing HIV infections, researchers at Sanford-Burnham Medical Research Institute have identified a protein that could improve the body’s immune response to HIV vaccines and prevent transmission of the virus.
There's a new game for serious gamers to explore on the Defense Advanced Research Projects Agency (DARPA) Verigames site (https://verigames.com/). Ghost Map Hyperspace, developed by Raytheon BBN Technologies, is the newest addition to a series of games being developed under DARPA sponsorship that empower gamers to do the work of software verification experts simply by playing games.
As water scarcity and quality issues grow in California and around the world, a new book co-edited by UCR water economist Ariel Dinar and water experts in Spain and Argentina examines the experience of 15 countries where conservation has been achieved through water-pricing incentive systems.
Wounded Warrior Project has approved a $15.7 million grant over three years for UCLA Health to expand its Operation Mend program to create a new, intensive structured treatment program for service members who have suffered mild traumatic brain injury and post-traumatic stress disorder.
An article in the June 2015 issue of Critical Care Nurse reviews post-acute transitional care as provided at a skilled nursing facility in western New York and examines the individual roles of various interdisciplinary team members, including progressive care nurses.
Does putting same-sex marriage in the public spotlight impede future policy gains for gay and lesbian couples? A new study says no, contrary to previous research on the topic.
There’s an urgent demand for new antimicrobial compounds that are effective against constantly emerging drug-resistant bacteria. Two robotic chemical-synthesizing machines at the Molecular Foundry have joined the search.
“Born Free” ruled the box office and the Beatles’ “Paperback Writer” topped the Billboard charts when UC Irvine’s first graduating class of 14 students received their diplomas. On June 25, 1966, in what is now the Libraries Gateway Study Center, they gathered with family and friends at tables draped in harvest-gold linens and shook the hand of founding Chancellor Daniel G. Aldrich Jr. This year – representing the scale by which the campus has grown – ceremonies for UCI’s 50th graduating class will stretch over four days in the Bren Events Center, and 7,057 Anteaters will participate. Ten school-based events will be held, featuring addresses by renowned leaders in business, technology, athletics and law.
People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.
Scientists at the University of California, San Diego and the Massachusetts Institute of Technology (MIT) have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present. The results of the new study, published in the May 27 issue of Science Translational Medicine, indicate that genetically-programmed probiotics may be useful for detecting liver cancer metastases early-on in the progression of the disease.
Children’s Hospital Los Angeles (CHLA) opened the doors of its new outpatient care center in Encino today. The pediatric medical facility, Children’s Hospital Los Angeles – Encino, will be staffed by physicians who are Board-certified in pediatric specialties and subspecialties, including hematology-oncology, nephrology, neurology, orthopaedics, pediatric surgery and urology.
A team of scientists from Berkeley Lab, JGI and UC Berkeley, simplified and sped up genome assembly, reducing a months-long process to mere minutes. This was primarily achieved by “parallelizing” the code to harness the processing power of supercomputers.
Accurately assessing pain in children in a clinical setting can be difficult. A study by researchers at the University of California, San Diego School of Medicine has demonstrated the validity of a new method for measuring pediatric pain levels using novel facial pattern recognition software.
A portable, finger-probe device successfully measured liver function in brain dead adult organ donors, a finding that could change the way organs are assessed and save thousands of dollars per transplant, a UCLA study has found.
Study explains why some melanoma tumors are resistant to BRAF inhibitor treatment
In Monster Proof, a new browser-based puzzle game from voidALPHA, players assume the role of a newly crowned ruler of a vast country in a fantasy setting. To win, they use problem-solving skills to answer illustrated mathematical questions. As each level is solved, the game crowd sources the software security process of formal verification.
A decoded message from a distant galaxy provided the plans for a Quantum Mechanical 3D printer in Left Brain Games’ puzzle shooter, Dynamakr. Players feed patterns into the machine to create designs for new devices never seen before on Earth—devices so advanced, they’re like magic. Game play allows non-experts to participate in improving software security in Phase 2 of DARPA’s Verigames project.
Sanford-Burnham Medical Research Institute at Lake Nona (Sanford-Burnham) today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. (Takeda) of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.
A new study predicts that researchers could use spiraling pulses of laser light to change the nature of graphene, turning it from a metal into an insulator and giving it other peculiar properties that might be used to encode information.
Scientists from The Scripps Research Institute Florida campus have been awarded nearly $2.2 million by the National Institute of Diabetes and Digestive and Kidney Diseases to advance an innovative approach to the treatment of obesity.
The Solar Energy Research Center (SERC), renamed to Chu Hall, opened today at Berkeley Lab. It will house laboratories and offices devoted to photovoltaic and electro-chemical solar energy systems designed to improve on what plants do and make transportation fuels. The building houses the lab’s programs in the Joint Center for Artificial Photosynthesis (JCAP) and the Kavli Energy NanoSciences Institute. The three-story, nearly 40,000 square-foot, building cost $59 million will house approximately 100 researchers and was named after former Berkeley Lab Director Steven Chu, who went on to become U.S. Energy Secretary.
The Huntington's Disease Clinical Research Center (HDCRC) at UC San Diego Health System has been designated a Center of Excellence by the Huntington’s Disease Society of America (HDSA). UC San Diego was one of only 29 centers nationwide to receive this prestigious designation, which recognizes centers for their elite multidisciplinary approach to Huntington's disease care and research.
The Millennium Drought in southeastern Australia forced Greater Melbourne, a city of 4.3 million people, to successfully implement innovations that hold critical lessons for water-stressed regions around the world, according to findings by UC Irvine and Australian researchers.
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