Feature Channels: Stem Cells

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Mayo Clinic的一项早期研究显示，源自患者自身脂肪的干细胞可进一步改善（而不仅是稳定）脊髓损伤患者的运动和感觉功能。

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Mayo Clinic and W. L. Gore & Associates Inc., a global materials science company, have formed a joint venture to advance the development of implantable cell therapies to treat debilitating conditions with no cure. Avobis Bio will combine Mayo Clinic's clinical and cell expertise and Gore’s expertise in material sciences to address some of the most challenging medical issues.

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Mayo Clinic researchers will present findings at the American Society of Hematology Annual Meeting Dec. 7–10 in Orlando. New Mayo Clinic studies to be presented include: DNA analysis identifies elevated risk factor for myeloma in individuals of African ancestry Study identifies more precise assessment measures for patients newly diagnosed with chronic lymphocytic leukemia Researchers develop method to assess cancer-fighting cell therapy's effectiveness

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A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma.

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For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients’ bodies, a study led by Dana-Farber Cancer Institute researchers suggests.

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Researchers have found a way to speed engineered-tissue creation using a novel bioprinter built for $2,000, they report in the journal Micromachines. Building blocks for the tissue are pre-grown spheroids of human induced-pluripotent stem cells that contain 200,000 cells per spheroid.

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A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.

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Researchers from the University of Georgia, Emory University School of Medicine and the University of Pittsburgh have received a $2.9 million grant from the National Institutes of Health to test a novel method of producing viable sperm cells from skin cells.

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DARPA-funded project called STOP PAIN aimed at the design of safer, more effective pain treatments Research to focus on understanding the biology of pain as a way to transform clinical care, help stem the public health crisis fueled by opioids Efforts will encompass expertise from fields including neurobiology, stem cell biology, artificial intelligence and computational and medicinal chemistry

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Las células madre derivadas del propio tejido adiposo del paciente constituyen un paso adelante en el mejoramiento (no solo en la estabilización) de las funciones motoras y sensoriales después de una lesión de la médula espinal, informa uno de los primeros estudios sobre el tema realizado por Mayo Clinic.

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UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions

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A study in Nature shows stem cell therapy helps hearts recover from a heart attack, although not for the biological reasons originally proposed two decades ago that today are the basis of ongoing clinical trials. The study reports that injecting living or even dead heart stem cells into the injured hearts of mice triggers an acute inflammatory process, which in turn generates a wound healing-like response to enhance the mechanical properties of the injured area.

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Stem cells derived from a patient's own fat offer a step toward improving — not just stabilizing — motor and sensory function of people with spinal cord injuries, according to early research from Mayo Clinic.

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Dana-Farber Cancer Institute researchers will present more than 40 research studies at the 61st American Society of Hematology (ASH) Annual Meeting on December 7-10 in Orlando, Fla.

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Mayo Clinic's Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS) and Children's of Alabama announce their collaboration within a consortium to provide solutions for patients with hypoplastic left heart syndrome, a rare and complex form of congenital heart disease in which the left side of the heart is severely underdeveloped.

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Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study. The study, published in the journal Gastroenterology, describes a new connection between the way cells consume fat and how genes regulate stem cell behavior in the intestines of mice.

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The 61st American Society of Hematology Annual Meeting and Exposition will take place Dec. 7–10 in Orlando, Florida

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Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.

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Dr. Eugene Chang was 25, recently engaged and halfway through a physical medicine and rehabilitation residency in Vancouver when he started feeling sick. Fatigue, dizziness and nausea took over his normally active lifestyle. Suddenly his bike to work was not so easy.