Feature Channels: Stem Cells

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30-Oct-2018 3:10 PM EDT
Twenty Years On, Measuring the Impact of Human Stem Cells
University of Wisconsin–Madison

A paper published today (Nov. 1, 2018) in the journal Cell Stem Cell describes the global scope and economic impact of stem cell science, including the clinical, industrial and research use of the cells.

   
30-Oct-2018 6:05 PM EDT
Relapsed leukemia flies under immune system’s radar
Washington University in St. Louis

A study from Washington University School of Medicine in St. Louis offers a potential explanation for why many AML patients experience a relapse after a stem cell transplant, and suggests a therapeutic approach that may help to place relapsed patients back into remission.

30-Oct-2018 2:40 PM EDT
Unique Type of Skeletal Stem Cells Found in 'Resting Zone' Are Actually Hard at Work
University of Michigan

Skeletal stem cells are valuable because it's thought they can heal many types of bone injury, but they're difficult to find because researchers don't know exactly what they look like or where they live.

Released: 30-Oct-2018 2:45 PM EDT
Study Uncovers Key Parts of Mechanism for Activating T Cells to Fight Cancer and Other Diseases
Dana-Farber Cancer Institute

In a study published online today by the journal Immunity, scientists at Dana-Farber Cancer Institute, Harvard Medical School, Vanderbilt University and colleagues at other institutions show how machinery within immune system T cells responds to outside signals and activates the cells to attack cancerous, infected, or otherwise diseased cells.

Released: 30-Oct-2018 12:05 PM EDT
Veterinarians Aim to Improve Safety and Efficiency in Development of New Drugs with in Vitro Model Based on Canine Stem Cells
Iowa State University

Iowa State University veterinary researchers are working with the Food and Drug Administration to advance an innovative in vitro model to study the oral absorption of therapeutic drugs without requiring testing on live animals. The work could lead to more efficient and safer development of new therapies for human and animal medicine.

Released: 29-Oct-2018 3:25 PM EDT
Scientists Neutralize Reactive Nitrogen Molecules to Enhance Cancer Immunotherapy
University of Notre Dame

Researchers at the University of Notre Dame studying tumors in prostate cancer models found that nitration of an amino acid can inhibit T-cell activation, thwarting the T-cell’s ability to kill cancer cells.

   
29-Oct-2018 9:30 AM EDT
Unapproved Therapies Cause Significantly More Patient Injuries Than Reported by Cell Therapy Clinics
American Academy of Ophthalmology (AAO)

A team of ophthalmologists went looking for scientific evidence in support of commercially available “cell therapy” for eye diseases. Not only did they find virtually none; they instead discovered a growing number of patients are being irreparably harmed by unapproved cell therapies.

Released: 24-Oct-2018 11:05 AM EDT
Case Western Reserve Researchers Receive $1.5M NIH Grant to Enhance Guidelines for Ethical Human-Animal Chimera Research
Case Western Reserve University

Insoo Hyun, PhD, and colleagues will identify ways of improving existing guidelines and ensuring professional accountability and responsibility in human-animal chimera research. The interdisciplinary bioethics project is supported by a three-year, $1.5 million grant from the National Human Genome Research Institute of the National Institutes of Health.

   
Released: 23-Oct-2018 9:00 AM EDT
Unique Collaboration Utilizing the International Space Station Accelerates Parkinson's Disease and Multiple Sclerosis Research
Space Tango Inc.

The National Stem Cell Foundation (NSCF), Summit for Stem Cell Foundation, The New York Stem Cell Foundation (NYSCF) Research Institute, and Space Tango today announced a bi-coastal research collaboration to study Parkinson's disease (PD) and primary progressive multiple sclerosis (PPMS) in microgravity.

Released: 22-Oct-2018 1:05 PM EDT
Scientists Awarded $8 Million to Develop Tissue Regeneration Therapy
Cedars-Sinai

A new method developed at Cedars-Sinai may revolutionize how severe injuries are treated by harnessing stem cells to regrow tissue damaged by major trauma, such as traffic accidents or war injuries.

21-Sep-2018 9:00 AM EDT
NOW AVAILABLE: Abstracts to be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018
American Neurological Association (ANA)

Embargoed abstracts to be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018 at the Hyatt Regency Atlanta are now available to journalists upon request.

   
16-Oct-2018 2:30 PM EDT
Stem Cell Transplantation Significantly Improves Survival and Function in Severe Scleroderma: 6-11-Year Follow-Up
American College of Rheumatology (ACR)

New research at the 2018 ACR/ARHP Annual Meeting builds on current evidence that hematopoietic stem cell transplantation can significantly improve long-term outcomes for patients with severe scleroderma when compared to use of conventional treatment with cyclophosphamide.

16-Oct-2018 2:30 PM EDT
Subset of Harder-to-Treat Systemic Sclerosis Patients May Respond to Stem Cell Transplantation
American College of Rheumatology (ACR)

Hematopoietic stem cell transplantation showed benefit in a subset of patients with systemic sclerosis who tend not to improve on immunosuppressive therapies like mycophenolate mofetil, according to new research findings presented this week at the 2018 ACR/ARHP Annual Meeting.

16-Oct-2018 2:30 PM EDT
Vascular Ultrasound Accurate, First-Line Imaging Test for Large Vessel Giant Cell Arteritis
American College of Rheumatology (ACR)

Vascular ultrasound is sensitive enough to use as a first-line imaging test in patients suspect to have giant cell arteritis, according to new research findings presented this week at the 2018 ACR/ARHP Annual Meeting.

Released: 18-Oct-2018 4:15 PM EDT
$5.1 Million Grant Will Fund Research to Develop a Stem Cell-Based Therapy for Blinding Eye Conditions
University of California, Los Angeles (UCLA), Health Sciences

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Stein Eye Institute have been awarded a $5.1 million grant from the California Institute for Regenerative Medicine to advance the development of a novel therapy for blinding retinal conditions.

15-Oct-2018 5:00 PM EDT
Scientists grow functioning human neural networks in 3D from stem cells
Tufts University

A team of Tufts University-led researchers has developed three-dimensional (3D) human tissue culture models for the central nervous system that mimic structural and functional features of the brain and demonstrate neural activity sustained over a period of many months.

Released: 15-Oct-2018 5:05 PM EDT
How Communication Among Cells Affects Development of Multicellular Tissue
Georgia Institute of Technology

Using a combination of computational modeling and experimental techniques, a research team has developed new information about how intercellular communication affects the differentiation of an embryonic stem cell colony over time.

Released: 15-Oct-2018 11:05 AM EDT
Stem cell biologist Sean Morrison elected to the National Academy of Medicine
UT Southwestern Medical Center

UT Southwestern Professor Dr. Sean Morrison, Director of the Children’s Medical Center Research Institute (CRI) at UT Southwestern, has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.

Released: 12-Oct-2018 2:05 PM EDT
HSS Researchers Launch Clinical Trial to Determine if Popular Stem Cell Therapy Can Protect Damaged Knees from Osteoarthritis
Hospital for Special Surgery

Led by Andreas H. Gomoll, MD, sports medicine surgeon at Hospital for Special Surgery (HSS), the study is looking at the effects on knee function of ReNu, an allograft product composed of human amniotic membrane and cells from the amniotic fluid.

Released: 12-Oct-2018 8:05 AM EDT
Cancer Stem Cells Use “Normal” Genes in Abnormal Ways
University of Colorado Cancer Center

University of Colorado Cancer Center study shows that "normal" gene CDK1 interacts with "abnormal" gene Sox2 to keep cancer stem cells "stemmy."



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