Feature Channels: Cell Biology

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Newswise: Fibroblast functionality: a pivotal piece in cancer's spreading puzzle
Released: 8-Aug-2024 10:05 AM EDT
Fibroblast functionality: a pivotal piece in cancer's spreading puzzle
Chinese Academy of Sciences

A new study reviews how cancer-associated fibroblasts (CAFs) influence lymph node metastasis. Researchers identified various CAF subsets that interact with the tumor microenvironment, promoting cancer spread. By targeting these specific subsets, new therapeutic strategies can be developed to inhibit metastasis, potentially improving patient outcomes. This breakthrough offers a deeper understanding of CAF heterogeneity and its role in cancer progression, paving the way for more effective cancer treatments.

Newswise: Tpex cells: the game-changer in targeted tumor immunotherapy
Released: 8-Aug-2024 10:05 AM EDT
Tpex cells: the game-changer in targeted tumor immunotherapy
Chinese Academy of Sciences

Progenitor exhausted CD8+ T (Tpex) cells have emerged as a pivotal component in tumor immunotherapy due to their unique ability to self-renew and rapidly proliferate. These cells have shown promise in expanding and differentiating into functional exhausted CD8+ T cells, significantly enhancing clinical outcomes. Understanding and leveraging Tpex cells can revolutionize immunotherapeutic strategies against cancer.

Newswise: Improving resolution and reducing noise in fluorescence microscopy with ensured fidelity
Released: 7-Aug-2024 12:05 AM EDT
Improving resolution and reducing noise in fluorescence microscopy with ensured fidelity
Chinese Academy of Sciences

Scientists developed a new method to improve resolution and reduce noise in fluorescence microscopy images. This technique utilizes mathematical tools to analyze and enhance image details, specifically addressing the fidelity of computational resolution extension. It outperforms existing methods by boosting signal-to-noise ratio and achieving higher resolution without introducing artifacts. This paves the way for more precise and informative imaging in various microscopy applications.

Newswise: Targeting protein has potential to treat leukemia, lymphoma
Released: 1-Aug-2024 10:05 AM EDT
Targeting protein has potential to treat leukemia, lymphoma
UT Southwestern Medical Center

Targeting a protein called ZFP574 suppressed leukemia in a mouse model of the disease, UT Southwestern Medical Center researchers showed in a new study. Their findings, published in PNAS (Proceedings of the National Academy of Sciences), could lead to new treatments for leukemias and lymphomas in cancer patients.

Newswise: Unraveling a Key Junction Underlying Muscle Contraction
30-Jul-2024 7:05 PM EDT
Unraveling a Key Junction Underlying Muscle Contraction
University of California San Diego

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.

   
Newswise: MD Anderson and collaborators to launch project studying T cells on International Space Station
Released: 31-Jul-2024 9:00 AM EDT
MD Anderson and collaborators to launch project studying T cells on International Space Station
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

   
Newswise: Cellular-Imaging-Core-Yuhan-Lien-Lab.jpg.webp?itok=gsNGfuQQ
Released: 25-Jul-2024 10:05 AM EDT
How Do You Take a Picture of a Cell? CHLA’s Cellular Imaging Core Has the Answers
Children's Hospital Los Angeles

They’re colorful. They’re fluorescent. And they wouldn’t look out of place hanging in a modern art museum.They are the photos captured by the Cellular Imaging Core, one of 10 research cores at The Saban Research Institute of Children’s Hospital Los Angeles.

Newswise: Pagliarini named HHMI Investigator
Released: 23-Jul-2024 12:05 PM EDT
Pagliarini named HHMI Investigator
Washington University in St. Louis

As an HHMI Investigator, David Pagliarini, PhD, the Hugo F. & Ina C. Urbauer Professor and a BJC Investigator in the Department of Cell Biology & Physiology will receive approximately $11 million in HHMI funding over a seven-year term.

Newswise: single_cell_calcium-1000px.jpg
Released: 23-Jul-2024 9:05 AM EDT
Pioneering the Cellular Frontier
Brookhaven National Laboratory

Scientists use a multimodal approach that combines hard X-ray computed tomography and X-ray fluorescence imaging to see the structure and chemical processes inside of a single cell.

Newswise: How Machine Learning Is Propelling Structural Biology
Released: 22-Jul-2024 2:05 PM EDT
How Machine Learning Is Propelling Structural Biology
Harvard Medical School

Cell biologist embraces new tools to study human development on the smallest scale

   
Released: 18-Jul-2024 8:05 PM EDT
New tech addresses manufacturing bottlenecks in a lifesaving blood cancer treatment
University of South Australia

Relapsed B-cell ALL is the leading cause of cancer-related deaths in children and young adults. UniSA research has shown the potential of new microfluidic technology, to improve the CAR T-cell manufacturing process by efficiently removing contaminating cancerous cells and other large white blood cells - potentially leading to greater access and lower costs of treatment.

Newswise: Children’s Research Institute at UT Southwestern discovers tumor growth fueled by nucleotide salvage
Released: 18-Jul-2024 10:05 AM EDT
Children’s Research Institute at UT Southwestern discovers tumor growth fueled by nucleotide salvage
UT Southwestern Medical Center

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children’s Medical Center Research Institute at UT Southwestern published in Cell.

Released: 17-Jul-2024 4:05 PM EDT
EveryLife Statement on the Creation of FDA Rare Disease Innovation Hub
EveryLife Foundation for Rare Diseases

he EveryLife Foundation for Rare Diseases commends the Food and Drug Administration (FDA) on today's announcement of its intention to create a Rare Disease Innovation Hub. Co-chaired by CDER Director, Dr. Peter Marks, and CBER Director, Dr. Patrizia Cavazzoni, the Hub will directly engage patients and the public to inform its strategic agenda.

Newswise: Sensor involved in regulating metabolic health identified
Released: 15-Jul-2024 10:05 AM EDT
Sensor involved in regulating metabolic health identified
UT Southwestern Medical Center

A protein receptor called PAQR4 found within fat cells appears to act as a sensor for ceramides, waxy lipids whose overabundance has been linked to a variety of metabolic disorders and cancers, a study led by UT Southwestern Medical Center researchers suggests. Their findings, published in Nature Metabolism, could eventually lead to drugs that reduce cellular ceramide levels, much like statins reduce cholesterol levels.

Newswise: Researchers Link Migraine Pain to Lack of Lymphatic System Drainage in Brain
Released: 11-Jul-2024 1:05 PM EDT
Researchers Link Migraine Pain to Lack of Lymphatic System Drainage in Brain
University of North Carolina School of Medicine

Researchers at the UNC School of Medicine have connected the dots between a small protein, the brain’s lymphatic system, and migraine pain.

Newswise: Stem Cell-Derived Therapy Shows Promise Against Treatment-Resistant Liver Cancer
Released: 9-Jul-2024 11:05 AM EDT
Stem Cell-Derived Therapy Shows Promise Against Treatment-Resistant Liver Cancer
University of California San Diego

Discover research from UC San Diego showing how stem cell-derived therapy, targeting treatment-resistant liver cancer through genetically modified NK cells, offers promising new avenues for immunotherapy.

Released: 2-Jul-2024 2:05 PM EDT
NanoCellect Launches VERLO: First Demonstration of Image-Based Sorting of Interacting Immune Synapsed Cells Followed by Confirmation of Immune Functionality
NanoCellect

NanoCellect Biomedical, a leader in microfluidic cell sorting technology, proudly announces the launch of VERLO™ Image-Guided Cell Sorter, a groundbreaking cell sorter poised to redefine the landscape of single-cell visualization and gentle flow cytometry analysis and cell sorting.

Newswise: UV Radiation Damage Leads to Ribosome Roadblocks, Causing Early Skin Cell Death
Released: 2-Jul-2024 1:30 PM EDT
UV Radiation Damage Leads to Ribosome Roadblocks, Causing Early Skin Cell Death
Johns Hopkins Medicine

In a recent study, researchers at Johns Hopkins Medicine suggest the cell’s messenger RNA (mRNA) — the major translator and regulator of genetic material — along with a critical protein called ZAK, spur the cell’s initial response to UV radiation damage and play a critical role in whether the cell lives or dies.

Released: 2-Jul-2024 11:05 AM EDT
Serendipity reveals new method to fight cancer with T cells
University of Wisconsin–Madison

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.



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