Feature Channels: Alzheimer's and Dementia

• share
• favorite_border

A barreira hematoencefálica — uma rede de vasos sanguíneos e tecidos que nutre e protege o cérebro de substâncias nocivas que circulam no sangue — é interrompida na doença de Alzheimer. No momento, pesquisadores e colaboradores da Mayo Clinic descobriram assinaturas moleculares únicas de disfunção da barreira hematoencefálica que poderiam apontar para novas formas de se diagnosticar e tratar a doença. Os resultados dessa descoberta estão publicados na Nature Communications.

• share
• favorite_border

La barrera hematoencefálica — una red de vasos sanguíneos y tejidos que nutre y protege al cerebro de las sustancias nocivas que circulan en la sangre, se interrumpe en la enfermedad de Alzheimer. En este momento, investigadores y colaboradores de Mayo Clinic han descubierto firmas moleculares únicas de disfunción de la barrera hematoencefálica que podrían apuntar a nuevas formas de diagnosticar y tratar la enfermedad. Los resultados de este hallazgo están publicados en Nature Communications.

• share
• favorite_border

Researchers from Johns Hopkins Medicine and the National Institutes of Health’s National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.

• share
• favorite_border

The San Diego Imperial Geriatric Education Center has received renewed funding from the Health Resources and Services Administration, allowing the center to relocate to UC San Diego.

• share
• favorite_border

Early memory loss has been linked to wealth loss, but research has mostly focused on investments. Four years ago, Wayne State University clinical geropsychologist Peter Lichtenberg, Ph.D., wondered what clues might be found in an older person’s financial decisions to indicate their vulnerability to financial victimization.

• share
• favorite_border

A machine learning tool developed by Cedars-Sinai investigators can answer questions about genes, drugs, and biochemical pathways associated with Alzheimer’s disease and other health conditions. Their findings were published today in the journal Bioinformatics.

• share
• favorite_border

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.

• share
• favorite_border

Alzheimer’s disease, a deadly brain disease than can cause loss of memory and mobility, affects millions of lives daily. June marks Alzheimer's and Brain Awareness Month, and Virginia Tech researchers are engaged in research meant to advance treatment for Alzheimer’s disease and assist caregivers of loved ones with dementia.

• share
• favorite_border

Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.

• share
• favorite_border

Certain drugs used to treat urinary symptoms due to an enlarged prostate may be associated with a reduced risk of dementia with Lewy bodies, according to a study published in the June 19, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• share
• favorite_border

June is Alzheimer’s & Brain Awareness Month. This month is crucial for highlighting the importance of brain health and supporting the millions of individuals and families affected by these conditions. Increased public awareness and understanding are essential as the number of people diagnosed with Alzheimer’s continues to rise.

• share
• favorite_border

More than a simple stopwatch, understanding how time cells work could ultimately aid in early detection of neurodegenerative diseases like Alzheimer's.

• share
• favorite_border

Chunyu Wang, M.D., Ph.D., professor of biological sciences and chemistry and chemical biology at Rensselaer Polytechnic Institute, has been awarded a five-year grant of more than $3.7 million by the National Institutes of Health’s National Institute on Aging to study Apolipoprotein E (ApoE) isoform interactions with heparan sulfate (HS) in Alzheimer’s disease (AD).

• share
• favorite_border

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson’s disease-causing alpha-synuclein.

• share
• favorite_border

People who experience prolonged depressive symptoms starting in young adulthood may have worse thinking and memory skills in middle age, according to a study published in the June 12, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• share
• favorite_border

People who give birth to infants less than 5.5 pounds may be more likely to have memory and thinking problems later in life than people who give birth to infants who do not have a low birth weight, according to a study published in the June 12, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

• share
• favorite_border

• share
• favorite_border

A study led by linguists from the NUS Faculty of Arts and Social Sciences has found that early linguistic signs of dementia can be detected through the study of the natural speech of senior Singaporeans. The novel study revealed that participants with memory-related mild cognitive impairment spoke less and used fewer, but more abstract, nouns that is consistent with the speech pattern of Alzheimer’s patients.