UAB researchers have made the first direct demonstration that fecal donor microbes remained in recipients for months or years after a transplant to treat the diarrhea and colitis caused by recurrent Clostridium difficile infections.
• A new calculator estimates the likelihood that a given patient who receives a kidney transplant from a particular living donor will maintain a functioning kidney.
• The calculator may be especially useful for kidney paired donation.
The University of Illinois at Chicago College of Medicine will launch a new center that will focus on understanding tissue regeneration and pioneering future developments in stem cell biology as a means to repair diseased organs and tissues.
Researchers from Houston Methodist and Italian super sports car maker Automobili Lamborghini are working together on new carbon fiber materials for implantable devices used in therapeutic drug delivery and orthopedics.
Combining a new hydrogel material with a protein that boosts blood vessel growth could improve the success rate for transplanting insulin-producing islet cells into persons with type 1 diabetes.
Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.
For some patients undergoing intestinal or multi-organ transplantation, closing the abdominal wall poses a difficult surgical challenge. Total abdominal wall transplantation provides an alternative for abdominal closure in these complex cases, according to a state-of-the-art approach presented in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Stanley C. Jordan, MD, a pioneering kidney transplant researcher, has received the International Society of Nephrology’s highest honor for groundbreaking work that improves the lives of kidney transplant patients while preserving the precious resource of donated organs.
• Patients who received kidney transplants from donors with diabetes had better survival compared with those who remained on the waitlist.
• Patients at high risk of dying while on the waitlist and those at centers with long wait times may benefit the most from transplantation with kidneys from diabetic donors.
In a study published today in the Clinical Journal of the American Society of Nephrology, researchers from the Perelman School of Medicine at the University of Pennsylvania, have found that the best chance of survival, for older patients, those who live in areas with long waits for transplantation, or those who already have diabetes, may come from accepting a kidney from a deceased donor who had diabetes.
A growing number of patients who suffer severe ankle arthritis are undergoing ankle replacement surgery, enabling them to walk again without pain.
Helping drive the trend are new implants and surgical techniques that are improving outcomes.
When a person loses a hand to amputation, nerves that control sensation and movement are severed, causing dramatic changes in areas of the brain that controlled these functions. As a result, areas of the brain devoted to the missing hand take on other functions. Now, researchers from the University of Missouri have found evidence of specific neurochemical changes associated with lower neuronal health in these brain regions. Further, they report that some of these changes in the brain may persist in individuals who receive hand transplants, despite their recovered hand function.
Researchers at Mayo Clinic have identified a possible cause for a rare infection in heart and lung transplant recipients: the donor. The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test. Originally, this bacterium was considered to reside exclusively in, and be a potential pathogen of, the area of the reproductive and urinary organs – the genitourinary tract.
Researchers examined the mechanisms of B cell immune reconstitution in pediatric patients who had undergone bone marrow transplantation and discovered a disruption in the maturation of B cells – critical to the immune system – preventing the production of antibodies that fight infection.
The agenda for the TVT (Transcatheter Valve Therapies) is now available online: http://www.crf.org/tvt/the-conference/agenda. TVT 2017 is a practical three-day course featuring the latest research and state-of-the-art techniques for transcatheter aortic and mitral valve therapies. For 10 years, TVT has provided healthcare professionals with the latest advances, tools, and techniques for the treatment of valvular heart disease using nonsurgical procedures.
Researchers at University of California San Diego School of Medicine, with collaborators across the nation, have determined that magnetic resonance elastography (MRE) can be an accurate, non-invasive tool to identify liver fibrosis in children. Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in children, and scarring of the liver, known as fibrosis, is a major determinant of clinical outcomes.
A new, personalized and noninvasive treatment using 3-D printed implants has been developed to help children born with abnormally small or missing eyes (microphthalmia/ anophthalmia, or MICA). The research is being presented at the 2017 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Baltimore, Md.