Feature Channels: Pharmaceuticals

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Released: 8-Nov-2022 11:55 AM EST
Study Finds NSAID Use and Age May Delay Conception in Spondyloarthritis Patients
American College of Rheumatology (ACR)

New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, showed that treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) and older age were associated with longer time to conception in spondyloarthritis patients.

Released: 8-Nov-2022 11:55 AM EST
New Analysis Finds Belimumab Improves Cutaneous Lupus Erythematosus in Patients with or without SLE
American College of Rheumatology (ACR)

New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, found that the B-cell inhibitor belimumab significantly improved cutaneous lupus erythematosus (CLE) whether or not patients also had systemic lupus erythematosus (SLE or lupus).

Released: 8-Nov-2022 11:50 AM EST
Study Finds Lower Risk of Severe Infection and Hospitalization with Belimumab Compared to Oral Immunosuppressants
American College of Rheumatology (ACR)

New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, found that the biologic B-cell inhibitor belimumab was associated with a lower risk of severe infections and hospitalizations compared to nonbiologic immunosuppressants.

Released: 8-Nov-2022 11:05 AM EST
Study Finds Gastrointestinal Symptoms in Systemic Scleroderma Unrelated to Disease-Specific Medications
American College of Rheumatology (ACR)

New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, found no clear association between immunosuppressive or anti-fibrotic medications and worsening gastrointestinal symptoms in early systemic scleroderma.

Released: 7-Nov-2022 10:05 AM EST
After Showing Early Potential, Cholesterol Medication Fenofibrate Fails to Cut Severe Symptoms or Death in COVID-19 Patients
Perelman School of Medicine at the University of Pennsylvania

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

Newswise: Epilepsy and Alzheimer's disease: Are there connections?
Released: 7-Nov-2022 9:35 AM EST
Epilepsy and Alzheimer's disease: Are there connections?
International League Against Epilepsy

Alzheimer's disease is a risk factor for epilepsy - and epilepsy is a risk factor for Alzheimer's. We spoke with Dr. Andrew Cole and Dr. Alice Lam about the latest research and some intriguing findings that suggest links between these two conditions.

Released: 6-Nov-2022 9:15 AM EST
Largest Randomized Trial Evaluates Steroids for Infant Heart Surgery
Duke Health

For more than four decades, doctors have been split on whether giving steroids during a pediatric open-heart surgery could be helpful for post-operative recovery. A new study is providing a bit more clarity, suggesting there are some benefits for certain kinds of patients.

Released: 5-Nov-2022 10:30 AM EDT
Comparative Study of Two Heart Failure Drugs Finds No Difference in Outcomes
Duke Health

In a head-to-head comparison of two so-called ‘water pills’ that keep fluid from building up in patients with heart failure, the therapies proved nearly identical in reducing deaths, according to a large study led by Duke Health researchers.

Released: 4-Nov-2022 10:55 AM EDT
Exploring How Diethylene Glycol Poisons the Kidney and the Combined Effects of St. John's Wort and Acetaminophen on the Liver
Society of Toxicology

A ToxSpotlight article in the November 2022 issue of ToxSci assesses the mechanism for cellular accumulation of diglycolic acid while another explores the effect of long-term St. John’s wort administration on acetaminophen-induced acute hepatotoxicity and the involved mechanisms.

Released: 4-Nov-2022 10:20 AM EDT
A Major Clinical Trial Shows How to Reduce the Risk of Stomach Bleeding Occasionally Caused by Regular Aspirin Use
University of Nottingham

A new study, led by experts at the University of Nottingham found that the risk of stomach bleeding caused by using aspirin long-term, can be reduced with a short course of antibiotics, potentially improving the safety of aspirin when used to prevent heart attacks, strokes and possibly some cancers.

Newswise: Cleveland Clinic Study Identifies Blood Pressure Drug as Potential Treatment for Black Patients with Alzheimer’s Disease
2-Nov-2022 11:00 AM EDT
Cleveland Clinic Study Identifies Blood Pressure Drug as Potential Treatment for Black Patients with Alzheimer’s Disease
Cleveland Clinic

CLEVELAND - Considering how patients from different ethnic groups respond to the same drug could be crucial to finding new Alzheimer’s disease treatments – a disorder the Alzheimer’s Association previously deemed a “silent epidemic” among Black adults. A Cleveland Clinic-led study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association showed that telmisartan, a drug currently prescribed for people with high blood pressure, is associated with a lower risk of Alzheimer’s specifically in Black patients over age 60. Insurance data from millions of adults over age 60 did not show the same potential effect in white patients.

Released: 3-Nov-2022 3:50 PM EDT
Largest Trial to Date Shows That COMP360 Psilocybin Reduces Depression Symptoms
King's College London

A multicentre clinical trial led by COMPASS Pathways across 22 international sites including Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and South London and Maudsley NHS Foundation Trust has found that a single 25mg dose of COMP360 psilocybin, alongside psychological support, had a significant impact in reducing symptoms of depression in participants with treatment-resistant depression.

   
Newswise: Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment
Released: 3-Nov-2022 2:25 PM EDT
Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment
University of California San Diego

Using human brain organoids, an international team of researchers has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses — the connections between brain cells that allow them to communicate with each other.

Released: 3-Nov-2022 12:55 PM EDT
Unlocking Hidden Connections Between Cell Death and Inflammation
Texas A&M University

As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.

Released: 3-Nov-2022 11:00 AM EDT
MD Anderson Research Highlights for November 3, 2022
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts.

   
Released: 3-Nov-2022 8:25 AM EDT
Final 2023 Medicare Physician Payment Rule Negatively Impacts Anesthesia Groups, Harms Patient Access to Surgical Care
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists calls on Congress to block a nearly 4.5% Medicare payment cut to anesthesiologists and other physicians included in the Centers for Medicare & Medicaid Services (CMS) 2023 Medicare Physician Fee Schedule (PFS) final rule released yesterday.

Newswise: Ochsner Pharmacist Makes Case for Reducing Use of Broad-Spectrum Antibiotics for Acute Kidney Infections
Released: 2-Nov-2022 5:40 PM EDT
Ochsner Pharmacist Makes Case for Reducing Use of Broad-Spectrum Antibiotics for Acute Kidney Infections
Ochsner Health

A new study led by Ochsner infectious diseases clinical pharmacist Kevin Lin, PharmD, was recently published in PLoS One, suggesting that oral cephalosporins are as safe and effective as the standard of care fluoroquinolones (FQs) for the treatment of acute kidney infections.

31-Oct-2022 7:05 AM EDT
Dapagliflozin Is Not Only Clinically Effective, but Also Cost Effective in Patients with Chronic Kidney Disease
American Society of Nephrology (ASN)

A recent analysis indicates that dapagliflozin is a cost-effective treatment in patients with chronic kidney disease in addition to standard of care.

Released: 2-Nov-2022 1:20 PM EDT
Many Middle-Aged Adults Wary of Taking Part in Studies of Dementia Prevention Drugs
Michigan Medicine - University of Michigan

Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.



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