UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.
Deva Chan, an assistant professor of biomedical engineering at Rensselaer Polytechnic Institute, is leading a team that will study the role that biomechanics plays in the production and function of hyaluronan in an effort to learn more about the factors that affect joint health and osteoarthritis. This research is being supported by a National Science Foundation Faculty Early Career Development (CAREER) Program Award.
Results from a new mouse study suggest that a new light-activated drug delivery method helps confine treatments to the joints, which could reduce whole-body side effects.
Advances in knee replacement surgery, such as robotic-assisted surgery and improvements in implant design and materials, make it a viable option for younger patients seeking pain relief.
Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The FDA has approved a new total wrist replacement device for people seeking relief from painful arthritis. The design is the culmination of three decades of award-winning research by Scott Wolfe, MD, a hand surgeon at Hospital for Special Surgery (HSS), and Joseph J. Crisco, III, PhD, director of the Bioengineering Laboratory at Brown University and Rhode Island Hospital.
The American College of Rheumatology (ACR) has released an official position statement concerning prior authorization for the approval of prescription medications, highlighting the significant burdens it creates for patients and rheumatology professionals. This process can result in a significant delay of care or treatments, treatment abandonment and potential harm to patients.
Racial/ethnic minorities, people with lower incomes, and other groups are less likely to receive office-based care for common musculoskeletal conditions, reports a nationwide study in Clinical Orthopaedics and Related Research® (CORR®), a publication of The Association of Bone and Joint Surgeons®. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Scientists at Fred Hutchinson Cancer Research Center identified a tiny protein in scorpion venom that rapidly accumulates in joint cartilage. Then they linked these mini-proteins with steroids to reverse inflammation in rats with arthritis. The researchers found that the drugs concentrated in the joints, potentially avoiding the body-wide toxicities and infection risks caused by nontargeted steroid treatment.
Decreased folate levels in the bloodstream have been associated with an increased risk of cardiovascular mortality in patients with rheumatoid arthritis, shedding light on why those patients are more susceptible to heart and vascular disease, according to research published today in JAMA Network Open by experts at The University of Texas Health Science Center at Houston (UTHealth).
This is the first, evidence-based guideline related to the management of reproductive health issues for all patients with rheumatic diseases. With 131 recommendations, the guideline offers general precepts that provide a foundation for its recommendations and good practice statements.
A new surgical procedure to repair a common wrist wrist injury is showing promise in relieving pain and restoring function, and in lowering the risk of progressive arthritis. The surgery is performed to repair a torn repair torn scapholunate ligament.
The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented at the State-of-the-Art Clinical Symposium (SOTA) in New Orleans on March 27-29.
University of Alabama's quarter back Tua Tagovailoa's hip injury. Stephen Curry's broken broken hand. 3-D printing technology that transformed a little girl's spine surgery. If you need an expert to discuss any of these timely topics, the American Academy of Orthopaedic Surgeons (AAOS) can provide expert sources to comment on musculoskeletal injury prevention, diagnosis and treatment.
The TSolution One® Surgical System combines two exclusive innovations to advance total joint replacement surgery. The system consists of TPLAN®, a 3D pre-surgical planning workstation and TCAT®, a computer assisted tool. The pre-surgical planning allows the surgeon to design and prepare, in a virtual environment, the patient's unique joint replacement plan using a choice of implant options. Total joint replacement surgery involves removing the diseased knee joint and replacing it with a joint implant. During the joint replacement surgery, the surgeon implements the patient's pre-planned procedure using the active robot, which prepares the joint according to the surgeon's plan for precise placement of implants.
Today, the American College of Rheumatology (ACR), in partnership with the Arthritis Foundation (AF), released the 2019 ACR/AF Guideline for the Management of Osteoarthritis of the Hand, Hip and Knee.
Tired of living with painful arthritic knees, 54-year-old Deborah Brown’s interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).
A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis (OA). Principal investigator of the study, Ari Isaacson, MD, clinical associate professor of vascular and interventional radiology in the UNC School of Medicine, says the results are positive.
Cedars-Sinai today announced a $20 million gift from Dr. and Mrs. Min H. Kao and the Kao Family Foundation to create the Kao Autoimmunity Institute to advance research and treatment of rheumatologic diseases. The gift also will establish the Scleroderma Program within the institute to provide interdisciplinary and integrated care for scleroderma patients and to support research, outreach, training and education to help those with the disease.
The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented at the Winter Rheumatology Symposium in Snowmass Village, CO on January 25 -31, 2020.
The American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) released the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease. It is the first criteria developed specifically for this recently recognized disease.
A Mayo Clinic-led study involving 3,276 patients has found that people with inflammatory bowel disease, Type 1 diabetes or blood clots may be at increased risk of developing rheumatoid arthritis. The study, published in Mayo Clinic Proceedings, also found that people who have rheumatoid arthritis are at increased risk of developing heart disease, blood clots and sleep apnea.
HSS researchers launched a study to find out if a “pre-habilitation” program – counseling by a peer coach who has already had a knee replacement – could empower and inform patients scheduled for the surgery, leading to better outcomes. The study found that such a program could be helpful.
Standard diagnostic methods are not adequate to identify prosthetic joint infections (PJIs) in patients with rheumatic diseases, according to findings from a new study by researchers from Hospital for Special Surgery (HSS) in New York City.
A new study finds that the community in which one lives influences where a patient receives postoperative care and rehabilitation after elective hip replacement surgery. An analysis of a large regional database found that patients in the least affluent communities were more likely to be discharged to an inpatient rehabilitation or skilled nursing facility rather than home care after surgery.
At the 2019 American College of Rheumatology/Association of Rheumatology Professionals annual meeting in Atlanta, experts from the HSS Education Institute at Hospital for Special Surgery (HSS) presented their method for developing and implementing effective educational programs for diverse patients with rheumatic conditions.
UAB pediatric rheumatologist Randy Cron gets calls from doctors around the globe asking if their patients have cytokine storm syndrome. Now he has co-authored the first textbook on this mysterious and deadly condition with his former trainee.
New research found that the 30-day death rate for Medicaid patients with systemic lupus erythematosus (SLE) who underwent coronary revascularization procedures for cardiovascular disease was double that of patients with diabetes mellitus who underwent the same procedures. This study will be presented at the 2019 ACR/ARP Annual Meeting (Abstract # 897).
Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis.
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, a treatment strategy guided by ultrasound information use does not appear to provide better treatment decisions in patients with early rheumatoid arthritis.
A new study found that patients with Down syndrome arthropathy continue to have an approximate year-long delay in diagnosis from the onset of their symptoms, and that optimal therapy for this condition remains unclear (Abstract # 2722).
A new study found that cancer patients with a pre-existing autoimmune disease receiving immune checkpoint inhibitors as treatment are likely to experience a flare.
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, both patients with rheumatoid arthritis whose disease onset occurred at an older age and those whose disease onset occurred earlier in life have similar improvements in clinical disease at 48 weeks after starting biologic disease-modifying antirheumatic drugs, as well as similar drug maintenance and adverse events discontinuation rates.
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.
New research presented at the 2019 ACR/ARP Annual Meeting suggests that opioids contribute no measurable benefit to quality of life or depression for patients with osteoarthritis (OA).
According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)
According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems to facilitate bone remodeling in these patients
In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found that the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis. Additionally, they found that pustular psoriasis is associated with arthritis onset two years earlier than the intercept interval; and there is an increased delay for nail involvement, plaque psoriasis or family history of psoriasis from psoriasis to arthritis by approximately two years for each characteristic.(Abstract #2854).
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, use of gadolinium-enhanced magnetic resonance imaging (MRI) in shoulders of patients with polymyalgia rheumatica may contribute to more accurate diagnosis and prediction of recurrence. Gadolinium-enhanced MRI displayed capsulitis, rotator cuff tendinitis and focal osteitis in shoulders that was relatively specific to patients with polymyalgia rheumatica (Abstract #1161).
The American College of Rheumatology (ACR), in partnership with the Arthritis Foundation (AF), is previewing draft recommendations from an updated treatment guideline for managing patients with hand, hip and knee osteoarthritis (OA) during two sessions at the 2019 ACR/ARP Annual Meeting in Atlanta.
The American College of Rheumatology (ACR) announced the 2019 recipients of its Master of the ACR designation, Awards of Distinction, and Distinguished Fellow Award honors during the opening lecture of the 2019 ACR/ARP Annual Meeting.
New, late-breaking research discovered that there are significant associations between anti-citrullinated protein bodies (ACPA), a characteristic biomarker for rheumatoid arthritis (RA), and industrial emissions of fine particles matter and sulfur dioxide.
The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), is previewing new draft recommendations for the treatment of systemic vasculitis at the 2019 ACR/ARP Annual Meeting in Atlanta.
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, there is a profound ongoing need for additional medications to control the signs and symptoms of juvenile idiopathic arthritis (JIA), despite the availability of several approved biologic disease-modifying antirheumatic drugs (biologics) (Abstract #1813).
New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor (TNFi) inhibitors first (Abstract# 2911).
New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus (Abstract #695).