Feature Channels: Diabetes

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2-Apr-2019 3:05 PM EDT
Insulin Insights
Harvard Medical School

Insulin triggers genome-wide changes in gene expression via an unexpected mechanism. The insulin receptor is transported from the cell surface to the cell nucleus, where it helps initiate the expression of thousands of genes. Targeted genes are involved in insulin-related functions and disease but surprisingly not carbohydrate metabolism. Findings outline a set of potential therapeutic targets for insulin-related diseases and establish a wide range of future avenues for the study of insulin signaling.

1-Apr-2019 8:45 AM EDT
Researchers Discover Groundbreaking Way to Treat Major Sight-Threatening Diseases of the Eye
Queen's University Belfast

Researchers from Queen’s University have discovered a new way of treating major diseases of the eye caused by the abnormal growth of new blood vessels.

Released: 2-Apr-2019 8:00 AM EDT
Genetics Society of America Awards 2019 George W. Beadle Award to Michael Snyder
Genetics Society of America

Michael Snyder, PhD, of Stanford University is the recipient of the 2019 Genetics Society of America (GSA) George W. Beadle Award for developing and disseminating widely-used technology for the simultaneous analysis of thousands of genes, RNA molecules, and proteins. The Beadle Award recognizes significant, sustained service to the genetics community that goes beyond an exemplary individual research career.

   
Released: 1-Apr-2019 9:00 AM EDT
Endocrine Society expert to testify before congressional committee about need for insulin affordability
Endocrine Society

Endocrine Society member and diabetes expert Alvin C. Powers, MD, will testify before the House Energy & Commerce Subcommittee on Oversight and Investigations Tuesday about the rising cost of insulin and the challenges this poses for individuals with diabetes who depend on the life-saving drug.

Released: 29-Mar-2019 3:05 PM EDT
Eliminar las “células zombi” alivia las causas de diabetes en ratones con obesidad
Mayo Clinic

Los investigadores y los colaboradores de Mayo Clinic demostraron que cuando se eliminan las células senescentes, también conocidas como “células zombi”, del tejido graso en ratones con obesidad, la gravedad de la diabetes y un rango de sus causas o consecuencias disminuyen o desaparecen.

Released: 29-Mar-2019 1:05 AM EDT
World first 3D-printed feet
University of South Australia

It’s gory, sticky and undoubtedly on the nose, but a blend of icing sugar, chicken stock and flexible resin is proving to be the just the right recipe for creating realistic foot ulcers as part of a world-first podiatric training initiative at the University of South Australia.

Released: 27-Mar-2019 2:05 PM EDT
Modified deep-learning algorithms unveil features of shape-shifting proteins
Oak Ridge National Laboratory

To function properly, proteins must morph into specific 3D shapes through a biophysical phenomenon called protein folding. Researchers at ORNL are using various deep-learning techniques to study the intermediate protein stages between the initial unfolded state and the final folded state, which are notoriously difficult to characterize. These methods could also help identify factors that cause proteins to “misfold” into dysfunctional shapes, a phenomenon often attributed as a leading factor in the development of diseases including Alzheimer’s, cardiovascular disorders, and diabetes.

   
Released: 26-Mar-2019 9:00 AM EDT
Removal of ‘zombie cells’ alleviates causes of diabetes in obese mice
Mayo Clinic

Mayo Clinic researchers and their collaborators have shown that when senescent cells — also known as “zombie cells” — are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear.

20-Mar-2019 9:00 AM EDT
Automated Drug Delivery System Combats Low Blood Sugar After Weight-Loss Surgery
Endocrine Society

A new automated drug delivery system can help prevent dangerously low blood sugar in patients who have undergone weight-loss surgery, according to a study to be presented Monday, March 25 at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Experimental Drug Reverses High Cholesterol, Obesity-Related Nonalcoholic Fatty Liver Disease in Animals
Endocrine Society

Scientists have discovered a novel molecular pathway for an enzyme inhibitor in humans that plays a direct role in the development of high cholesterol and nonalcoholic fatty liver disease, which they then were able to reverse in mice with an investigational drug. The study results will be presented Monday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La., by researchers from Northwestern University Feinberg School of Medicine in Chicago, Ill.

20-Mar-2019 9:00 AM EDT
Time-restricted eating may help prevent breast cancer, mouse study suggests
Endocrine Society

Changing when you eat rather than what you eat may prove to be a dietary intervention against breast cancer, suggests a new mouse study to be presented Saturday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Walking downhill after meals boosts bone health in postmenopausal women with diabetes
Endocrine Society

Walking downhill after eating can reduce bone resorption, the process in which old bone is broken down and removed from the body, in postmenopausal women with diabetes, according to research to be presented Sunday, March 24 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La. Walking uphill does not have the same benefit, the study found.

20-Mar-2019 9:00 AM EDT
Screen Time Plus Snacking a Risk for Metabolic Disorder in Teens
Endocrine Society

Teens who sit for hours watching TV, using the computer or playing video games while eating unhealthy snacks are at increased risk for a group of risk factors for heart disease and diabetes, according to research to be presented Monday, March 25 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Race, ethnicity influence fracture risk in people with diabetes
Endocrine Society

Caucasians and Hispanics with diabetes have a greater risk of fracture compared to those without diabetes, while African Americans with diabetes have little to no additional fracture risk, according to a study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Obesity may play role in reproductive problems in women with type 1 diabetes
Endocrine Society

Obesity may play a role in reproductive problems in women with type 1 diabetes, according to a new study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Improved PCOS symptoms correlate with gut bacterial composition
Endocrine Society

Symptoms of polycystic ovary syndrome (PCOS) improved with exposure to healthy bacteria in the gut, according to a study in a mouse model of this common women’s endocrine disorder. The study results will be presented Monday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
A1c test misses many cases of diabetes
Endocrine Society

Using the hemoglobin A1c blood test to diagnose diabetes tends to underestimate the prevalence of the disease, according to a new study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
New Hybrid Closed Loop Insulin Pump Proves Hard to Use for Some Patients with Diabetes
Endocrine Society

Among first-time users of a new insulin pump that automatically delivers insulin to people with type 1 diabetes, nearly one-fifth stopped using the device, primarily because of difficulties meeting the technical demands system, researchers say. Results of a real-world study of the hybrid closed loop insulin pump (Medtronic MiniMed 670G) will be presented Sunday at the Endocrine Society’s annual meeting in New Orleans, La.

20-Mar-2019 9:00 AM EDT
Older adults with type 1 diabetes often not aware of hypoglycemia
Endocrine Society

Older adults with type 1 diabetes typically have low blood sugar, or hypoglycemia, for more than an hour a day, suggests research to be presented Monday, March 25 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

22-Mar-2019 11:20 AM EDT
Treating Diabetes in Older Adults Requires Simpler Medication Regimens, Looser Glycemic Targets
Endocrine Society

Simplifying medication regimens and tailoring glycemic targets in older adults with diabetes improves adherence and avoids treatment-related complications, according to a Clinical Practice Guideline issued today by the Endocrine Society. The Society debuted the guideline during a press conference on the opening day of ENDO 2019, its annual meeting in New Orleans, La.



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