Medical reversal—when accepted medical interventions are abandoned because they are found to be ineffective—is the “most important problem in medicine today,” according to the authors of a new book: Ending Medical Reversal. Reversals are distressingly common. Reforms are overdue.
Second phase of the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP2) aims to establish a new system of diagnosis for psychotic diseases based on biomarkers, and guide the development of novel therapies.
The brain uses similar computations to calculate the direction and speed of objects in motion whether they are perceived visually or through the sense of touch.
This fall, UChicago Medicine Comer Children’s Hospital experts across a dozen pediatric subspecialties will see patients at new outpatient clinics at Edward Hospital in Naperville and Elmhurst Hospital.
The gut bacteria of infants who developed tolerance to cow’s milk after treatment with probiotic formula showed significant differences from those who remained allergic, according to a new study published September 22, 2015, in The ISME Journal by scientists from the University of Chicago, Argonne National Laboratory and the University of Naples Federico II, Italy.
Leading researchers from Chicago’s academic medical centers and other institutions will meet at the American Heart Association’s 2015 Chicago Research Network Symposium, hosted by University of Chicago Medicine’s Section of Cardiology, on Friday, September 18, from 9 a.m. to 5 p.m.
In a move to create a more comprehensive system of needed trauma and emergency care for Chicago's South and Southwest side communities, Sinai Health System and the University of Chicago Medicine are partnering to build and operate a Level 1 adult trauma center and to expand emergency services. The UChicago Medicine and Sinai Health System new joint Level 1 adult trauma center will be at Holy Cross Hospital, part of the Sinai Health System.
Protein aggregates that form after a cell is exposed to heat appear to be part of an organized response to stress. The findings shed new light on the biological nature of protein aggregates, which have been widely considered to be toxic dead-end products, but are increasingly being recognized as a new layer of cellular organization.
The Center for Asian Health Equity, a partnership between the University of Chicago Medicine and the Asian Health Coalition, has received a five-year, $3.5 million federal grant from the Centers for Disease Control and Prevention to increase colorectal cancer screenings, particularly among underserved communities in Cook County.
Through the use of custom-engineered synthetic proteins known as monobodies, scientists have now resolved the atomic structure of the fluoride ion. The study sheds light on the evolution of these channels and enables new approaches to modify their function, with potential applications such as the development of novel antibiotics.
The University of Chicago Medicine has been named a National Pancreas Foundation Center, one of only 30 facilities in the country to receive the prestigious designation from the health advocacy group. The National Pancreas Foundation created the NPF Center designation in order to help patients find high-quality, multidisciplinary care.
Scientists have developed a novel approach to control the activity of enzymes through the use of synthetic, antibody-like proteins known as monobodies. The findings have widespread implications for a broad range of industrial, scientific and medical applications in which enzymes are used.
The first whole genome analysis of an octopus reveals unique genomic features that likely played a role in the evolution of traits such as large complex nervous systems and adaptive camouflage. The findings are published in Nature on Aug 12, 2015.
A new computational method developed by scientists from the University of Chicago improves the detection of genes that are likely to be causal for complex diseases and biological traits. The method, PrediXcan, has the potential to identify gene targets for therapeutic applications faster and with greater accuracy than traditional methods.
.The University of Chicago Medicine has become the first transplant center to contribute to the Illinois Transplant Fund (ITF), a new not-for-profit that provides financial support for organ transplants to qualified uninsured residents of northern and central Illinois and Northwest Indiana. The medical center's initial $100,000 donation will be followed by additional contributions of up to $400,000 total over the next three years.
A large-scale genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma. No significant associations between telomere length and other cancer types or subtypes were observed.
Anjuli Nayak, a renowned allergist and immunologist from Bloomington who received cancer treatment at the University of Chicago Medicine, is endowing a $3.5 million professorship at the medical center for leukemia research.
Internationally recognized experts will lead a two-day conference in Chicago to educate peers on emerging robotic treatments and procedures for pediatric urology patients; live stream available in India.
The weekend begins with a reception on Friday evening and includes a full day of presentations and discussion groups on Saturday and a half day on Sunday. Our featured speaker will be Dr. Issam Awad, Chair of the Angioma Alliance Scientific Advisory Board. There will be panel discussions on rehabilitation and on coping/self-care. We will have a separate program for children and teens. Please check our website at www.angioma.org/pages.aspx?content=447 for full conference details.
The NIH has awarded a $2.7 million grant to a team from the University of Chicago, Argonne National Laboratory and the University of South Florida to study the gut microbiomes of premature infants.
The Game Changer Chicago Design Lab at the University of Chicago, has received a five-year, $1.2 million federal grant to investigate gameplay and game design as a way to enhance
The investigational drug patiromer quickly reduced elevated blood-potassium levels—a common life-threatening side effect of treatment for chronic diabetic kidney disease. In this year-long study of more than 300 patients, patiromer kept potassium levels under control for the length of the trial.
The University of Chicago Medicine is among 22 centers of excellence across the country chosen by Food Allergy Research & Education (FARE) to be inaugural members of its FARE Clinical Network, which will work to accelerate development of therapies and raise the standard of care for people with food allergies.
Organ transplant rejection in hosts that were previously tolerant may not be permanent. Using a mouse model of cardiac transplantation, scientists from the University of Chicago found that immune tolerance can spontaneously recover after infection-triggered rejection, and that hosts can accept subsequent transplants as soon as a week after.
The first comprehensive analysis of the woolly mammoth genome reveals extensive genetic changes that allowed mammoths to adapt arctic life, including skin and hair development, insulin signaling, fat biology, and even traits such as small ears and short tails. A mammoth gene for temperature sensation was resurrected in the lab as a functional test.
The University of Chicago Medicine and Little Company of Mary Hospital and Health Care Centers are partnering to expand care for infants and children by developing a subspecialty center on the community hospital’s Evergreen Park campus that will provide enhanced neonatology and pediatric services.
Scientists from the University of Chicago have developed a new technique that calibrates a commonly-used tool in epigenetic experiments with an internal standard - dramatically improving accuracy and the development of therapeutics against diseases linked to epigenetic changes.
Few heart specialists make use of published information about interactions between drugs used to treat cardiovascular disease and the genetic variations that affect how patients respond to them. So physicians at U Chicago and Stanford combed through the literature on the pharmacogenomics of the leading cardiovascular drugs and compiled summaries.
Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more patients.
Messenger RNA (mRNA) levels dictate most differences protein levels in fast-growing cells when analyzed using statistical methods that account for noise in the data, according to a new study by researchers from the University of Chicago and Harvard University.
Newly evolved genes can rapidly assume control over fundamental functions during early embryonic development, report scientists from the University of Chicago. The findings suggest that evolutionary changes to the genetics of fundamental biological processes occur more frequently than previously thought.
Post-surgical leaks that develop after a segment of the colon has been removed and stitched back together often are caused not by negligence or technical error but by bacteria in the bowel that elude antibiotics, according to new evidence about this devastating complication of gastrointestinal surgery.
The University of Chicago Medicine was named one of the safest hospitals in the country for the seventh consecutive time by the prestigious and independent Leapfrog Group. UChicago Medicine is one of only 182 U.S. hospitals, out of about 5,000, to receive an A in each survey.
Latino adults with diabetes who participated in a church-based education program reported eating less high-fat food and exercising more following a trial intervention program run by researchers from University of Chicago’s Department of Medicine.
After more than eight months of bargaining, the University of Chicago Medical Center and National Nurses United reached a tentative agreement for a new collective bargaining agreement just before midnight Monday.
On May 1, 2015, the University of Chicago Celiac Disease Center is hosting the annual Spring Flours Gluten-Free Gala. The event will feature a multi-course, gluten-free dinner created by some of Chicago’s best chefs and bakers.
University of Chicago Medicine: Background, b-roll and photos for journalist use.
Researchers have unraveled the precise mechanism that cells in the carotid bodies use to detect oxygen levels in the blood and send signals through the carotid sinus nerve to stimulate or relax breathing rates.
A natural compound from magnolia bark can protect the heart from hypertrophy by activating SIRT3, a protein associated with delayed aging, stress resistance and metabolic regulation. Injected honokiol protected stressed mice, preventing excess growth of cardiac muscle cells and fibrosis.
Kenneth S. Polonsky, MD, the Richard T. Crane Distinguished Service Professor of Medicine, has been appointed to a second five-year term as dean of the Biological Sciences Division and the Pritzker School of Medicine and executive vice president for medical affairs at the University of Chicago. The reappointment is effective Oct. 1, 2015.
An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study. The drug appears to enhance an innate cellular mechanism that protects myelin-producing cells.
Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles. The new method represents a significant technological advance with potential advantages over current optogenetic methods, including possible use in the development of therapeutics.
The MacArthur Foundation has awarded $1 million over two years to Ci3’s Game Changer Chicago Design Lab at the University of Chicago to advance its work developing game-based learning experiences that promote sexual and reproductive health among urban youth.
The University of Chicago Pritzker School of Medicine moved up a notch to regain its top 10 status as one of the country’s best medical schools and its primary care program scored its strongest rating since 2010, according to the latest edition of U.S. News & World Report’s “Best Graduate Schools.”
Lack of sleep can elevate levels of free fatty acids in the blood, accompanied by temporary pre-diabetic conditions in healthy young men. Getting enough sleep could help counteract the current epidemics of diabetes and obesity.
Antibodies that protect against H7N9 avian flu, which emerged in China in 2013 and sparked fears of a global pandemic, have been isolated in individuals who received seasonal flu vaccinations and appear to broadly neutralize H7 viruses.
The fossils of two interrelated ancestral mammals, newly discovered in China, suggest that the wide-ranging ecological diversity of modern mammals had a precedent more than 160 million years ago.
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