The Jefferson College of Graduate Studies has been renamed the Jefferson Graduate School of Biomedical Sciences (JGSBS) to better reflect the school’s breadth of degrees and programs and overall mission.
Breast cancer patients whose tumors lacked the retinoblastoma tumor suppressor gene (RB) had an improved pathological response to neoadjuvant chemotherapy, researchers at Thomas Jefferson University Hospital and the Kimmel Cancer Center at Jefferson report in a retrospective study published in a recent online issue of Clinical Cancer Research.
Researchers at the Kimmel Cancer Center at Jefferson have shown that senescence (aging cells which lose their ability to divide) and autophagy (self-eating or self-cannibalism) in the surrounding normal cells of a tumor are essentially two sides of the same coin, acting as “food” to fuel cancer cell growth and metastasis.
The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue of Cancer Research.
Jefferson’s Kimmel Cancer Center and the Department of Radiology at Thomas Jefferson University received a five-year, $2.6 million grant from the National Institutes of Health (NIH) to investigate a potentially revolutionary method that can stage prostate cancers and detect recurrent disease so accurately, it would significantly reduce the number of confirmation biopsies.
Surgeons at the Rothman Institute at Jefferson were recently voted by their peers as three of the top 28 spine surgeons in the country. The complete list appears on the popular industry website, Orthopedics This Week (http://ryortho.com/).
To improve the quality of life in gay men and minorities treated for prostate cancer, a greater awareness of ethnic and sexual preference-related factors is needed to help men choose a more-suitable treatment plan, researchers from Thomas Jefferson University Hospital conclude in a literature review published May 1 in Nature Reviews Urology.
Scott Waldman, M.D., Ph.D., Chair of the Department of Pharmacology and Experimental Therapeutics at Thomas Jefferson University, has been awarded a Commonwealth Universal Research Enhancement (CURE) grant for almost $750,000 to help advance a molecular diagnostic test for colon cancer into commercialization.
(NEW ORLEANS) – Howard Weitz, M.D., FACP, FACC, director of the division of Cardiology and the Jefferson Heart Institute at Thomas Jefferson University Hospital, and Bernard L. Segal Professor of Medicine at Jefferson Medical College of Thomas Jefferson University and his colleagues will again lead a pre-course session, Cardiology for the Internist, at the American College of Physicians’ Internal Medicine 2012 in New Orleans. The session will educate internists on the diagnostic, preventative and therapeutic approaches to the patient at risk for or with known cardiovascular disease.
Thomas Jefferson University Hospital announces the opening of its new Jefferson Barrett’s Esophagus Treatment Center, one of only a few dedicated Barrett’s centers in the country and the first multidisciplinary center solely dedicated to treating Barrett’s esophagus disease in Philadelphia.
Edith Mitchell, M.D., FACP, a medical oncologist at Jefferson’s Kimmel Cancer Center, has been named the 2012 recipient of the American Society of Clinical Oncology Humanitarian Award for her personification of the society’s mission and values, and for going above and beyond the call of duty in providing outstanding patient care.
Hepatitis B-infected patients with significantly longer telomeres—the caps on the end of chromosomes that protect our genetic data— were found to have an increased risk of getting liver cancer compared to those with shorter ones, according to findings presented by researchers at Jefferson’s Kimmel Cancer Center at the American Association for Cancer Research Annual Meeting 2012.
Participation in a home walking program can lead to a significant improvement in quality of life, fatigue levels and physical functioning of post-surgery pancreatic cancer patients, according to findings from a randomized, controlled study by researchers at Thomas Jefferson University and Jefferson School of Nursing – set to appear in the Journal of the American College of Surgeons on April 1.
Thomas Jefferson University Hospital’s Department of Radiation Oncology has unveiled the region’s only image-guided brachytherapy suite, where patients can have radiation imaging, planning and treatment in a single location without being moved.
Researchers at Thomas Jefferson University Hospital in Philadelphia and a multicenter team of investigators have found that carotid artery stenting (CAS) is safe and effective in patients age 70 and older.
Researchers from Thomas Jefferson University Hospital discovered that blockages in the right coronary artery and those in bending areas of the coronary artery are the most common places for coronary dissection, a tear in the artery that can occur during balloon angioplasty of the coronary arteries.
Researchers at the Kimmel Cancer Center at Jefferson have demonstrated for the first time that the metabolic biomarker MCT4 directly links clinical outcomes with a new model of tumor metabolism that has patients “feeding” their cancer cells. Their findings were published online March 15 in Cell Cycle.
The ARCHES Project, a program of Thomas Jefferson University Hospitals, was one of 10 programs from across the country named a Program of Excellence by the Hospital Charitable Service Awards, a national program sponsored by Jackson Healthcare.
Jefferson physicians are seeing a growing trend of more colorectal cancer patients under 50, some even under 40, said Scott D. Goldstein, M.D., Director of the Division of Colorectal Surgery at Thomas Jefferson University Hospital
Researchers at the Rothman Institute at Jefferson have shown that patients who receive surgery less than 24 hours after a traumatic cervical spine injury suffer less neural tissue destruction and improved clinical outcomes. The results of their study, the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS) are available in PLoS One.
Researchers at Thomas Jefferson University Hospital determined that mantra-based meditation can have a positive impact on emotional responses to stress, fatigue and anxiety in adults with memory impairment and memory loss. Their findings are published in the recent issue of the Journal of Alternative and Complementary Medicine.
National thought leaders in geriatric oncology will gather at a unique symposium at the Kimmel Cancer Center at Jefferson in Philadelphia on Friday, March 9, 2012, where they will present an overview of the latest advances in the understanding and treatment of cancer in older adults in an effort to impact patient care.
In an effort to reduce and eventually eliminate cancer disparities among adults in the Philadelphia region, the Kimmel Cancer Center at Jefferson has established the Center to Eliminate Cancer Disparities.
Takemi Tanaka, Ph.D., of Thomas Jefferson University’s School of Pharmacy and the Kimmel Cancer Center, received a $50,000 grant toward her breast cancer research, as part of the Pennsylvania Breast Cancer Coalition’s “Refunds for Breast and Cervical Cancer Research” initiative.
After he failed to heed the first big warning about his heart, John Magri was lucky to survive the second. Magri’s first heart attack at age 46 didn’t faze him much. He didn’t follow his doctor’s orders to start to eat a healthier and to quit smoking. Moreover, the South Jersey-man took his medication, a blood thinner necessary to prevent the coronary stent he got after the first heart attack from becoming blocked, only sporadically. A second heart attack in January – just a year and a half after the first – got Magri’s attention. He is lucky to be alive and knows it.
Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy, a study from researchers at Jefferson’s Kimmel Cancer Center suggests.
Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.
In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have shown that the accepted method of diagnosis, measuring a patients’ serum white blood cell count (WBC) and the percentage of neutrophils (PMN%) in the synovial fluid, has a minimal role in the determination of PJI.
(PHILADELPHIA) – Researchers at the Rothman Institute at Jefferson examined data on patients being treated for lumbar stenosis and the degenerative spine condition spondylolisthesis and found that patients who received epidural steroid injections (ESI) had a higher rate of crossover to surgery and fared worse in physical health and bodily pain versus those who did not receive ESI, dispelling their pre-study hypothesis.
Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows leukocyte esterase reagent (LE) strips, common in diagnosing urinary tract infections, can also have a role in rapid diagnosis of PJI.
Researchers at Kimmel Cancer Center at Jefferson show that cyclin D1 overexpression associates with chromosomal instability in luminal B breast cancer.
A population-based analysis looking at almost 13,000 cases revealed that men who received brachytherapy alone or in combination with external beam radiation therapy had significantly reduced mortality rates.
On Sunday, January 29, three physicians and two nurses from the Thomas Jefferson University Hospital Emergency Department (ED) will travel to Sierra Leone to help improve the quality of healthcare and its delivery within the impoverished West African country. The Jefferson physicians will stay for two weeks and the nurses for six weeks. This will be the second trip for Jefferson’s team in a little more than a year.
Lung cancer, the leading cause of cancer deaths in the U.S. and worldwide, is often caught too late. Thomas Jefferson University Hospital experts in pulmonary and critical care, radiology, thoracic surgery, and medical and radiation oncology have teamed up to launch a novel effort to screen, diagnose and treat lung cancer in its earliest stages.
Integrative medicine, the field of medicine which combines the use of conventional and complementary techniques in reaching health and wellness goals, is now available for pediatric patients through the Integrative Pediatrics program at the Jefferson-Myrna Brind Center of Integrative Medicine. Under the guidance of a board-certified pediatrician, the program combines the best evidence-based conventional medicine with a variety of proven lifestyle therapies and complementary techniques for pediatric patients from birth through 21 years.
Allergies to Plavix®, also know by its chemical name, Clopidogrel occur in about six percent of patients given the drug, vital for the prevention of life-threatening stent thrombosis after angioplasty and percutaneous coronary interventions. Researchers at Thomas Jefferson University found that a combination of steroids and antihistamines can successfully alleviate the allergic reaction and enable patients to remain on the drug. Until now, hypersensitivity required drug interruption, placing the patient at risk for restenosis or a major coronary event.
Thomas Jefferson University Hospital’s Bariatric Surgery Program, along with David Tichansky, M.D., F.A.C.S., the program director, have been awarded a full three-year accreditation by the American Society of Metabolic and Bariatric Surgery (ASMBS) Bariatric Surgery Center of Excellence, one of the field’s highest levels of recognition.
Researchers in Family and Community Medicine at Thomas Jefferson University recently found that obesity was linked to higher rates of prostate cancer screening across all races/ethnic differences and lower rates of cervical cancer screening, most notably in white women. Their study on the role of obesity in cancer screening rates for prostate, cervical as well as breast and colorectal cancers across race/ethnicity and gender is examined in the current issue of the Journal of Obesity.
Researchers from Thomas Jefferson University’s Center for Translational Medicine found that reducing levels of a well-known, cell-surface protein known as N-cadherin slowed down the pancreatic cancer cells’ mobility and prolonged survival in mice.
Richard Pestell, M.D., Ph.D., FACP, Director of the Kimmel Cancer Center at Jefferson, has been named a 2011 Fellow of the American Association for the Advancement of Science.
Physicians at the Jefferson Hospital for Neuroscience are tackling a particularly aggressive brain cancer that even surgery, chemotherapy and radiation often fail to treat with a promising new immunotherapy to attack a patient’s tumor with their own cancer cells.