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Released: 26-Sep-2024 6:00 AM EDT
Uso De Tesoura Molecular Para Aprimorar a Terapia Com CéLulas CAR-T
Mayo Clinic

Pesquisadores da Mayo Clinic investigaram as bases moleculares do câncer e descobriram uma nova razão pela qual o receptor de antígeno quimérico (terapia com células CAR-T) não funciona em alguns pacientes. Essa descoberta estimulou novas estratégias que incorporam anticorpos e edição genética para melhorar os resultados desse tratamento inovador para os pacientes. Esta pesquisa do Dr. Saad Kenderian, consultor em hematologia da Mayo Clinic, foi publicada na Nature Communications.

Released: 26-Sep-2024 6:00 AM EDT
Uso De Tijeras Moleculares Para Mejorar La Terapia Con CéLulas CAR-T
Mayo Clinic

Investigadores de Mayo Clinic investigaron las bases moleculares del cáncer y descubrieron una nueva razón por la cual el receptor de antígeno quimérico (terapia con células CAR-T) no funciona en algunos pacientes. Este hallazgo estimuló nuevas estrategias que incorporan anticuerpos y edición genética para mejorar los resultados de este tratamiento innovador para los pacientes. Esta investigación del Dr. Saad Kenderian, consultor en hematología de Mayo Clinic, fue publicado en Nature Communications.

Released: 26-Sep-2024 3:00 AM EDT
استخدام المقص الجزيئي لتحسين العلاج بالخلايا التائية ذات مستقبلات المستضد الخيمرية
Mayo Clinic

روتشستر، ولاية مينيسوتا — توصل باحثو مايو كلينك إلى الأسس الجزيئية للسرطان واكتشفوا سببًا جديدًا لفشل مستقبلات المستضد الخيمرية (العلاج بالخلايا التائية) مع بعض المرضى. وقد عزز هذا الاكتشاف وضع استراتيجيات جديدة تدمج الأجسام المضادة وتعديل الجينات لتحسين نتائج هذا العلاج المتقدم للمرضى. نُشر هذا البحث الذي أجراه سعد كينديريان، بكالوريوس الطب والجراحة، استشاري طب الدمويات في مايو كلينك، في مجلة نيتشر كوميونيكيشنز (Nature Communications).

Newswise: Alternating Currents for Alternative Computing with Magnets
Released: 26-Sep-2024 1:05 AM EDT
Alternating Currents for Alternative Computing with Magnets
University of Vienna

A new study conducted at the University of Vienna, the Max Planck Institute for Intelligent Systems in Stuttgart, and the Helmholtz Centers in Berlin and Dresden takes an important step in the challenge to miniaturize computing devices and to make them more energy-efficient.

Newswise: In an Era of Climate Change, Clean Water and Reliable Water Storage for Floods and Droughts Is a Possibility!
Released: 26-Sep-2024 12:00 AM EDT
In an Era of Climate Change, Clean Water and Reliable Water Storage for Floods and Droughts Is a Possibility!
National Research Council of Science and Technology

Dr. Seongpil Jeong and Kyungjin Cho of the Center for Water Cycle Research at the Korea Institute of Science and Technology (KIST) have developed an aquifer storage technique that could improve the potential for stable water storage.

Newswise: NEJM: Results From Targeted Therapy for Ulcerative Colitis Study
Released: 25-Sep-2024 7:05 PM EDT
NEJM: Results From Targeted Therapy for Ulcerative Colitis Study
Cedars-Sinai

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

Released: 25-Sep-2024 5:05 PM EDT
Patients With Moderate-to-Severe Ulcerative Colitis May Find Significant Relief as New Treatment Option Shows Good Results in Clinical Trial
Mount Sinai Health System

A phase 2 trial of a monoclonal antibody known as tulisokibart for moderate-to-severe ulcerative colitis (UC) showed promising results for those who have not responded to conventional inflammatory bowel disease (IBD) treatment. The results were reported Thursday, September 26, in The New England Journal of Medicine.

24-Sep-2024 1:35 PM EDT
Single-Dose Gene Therapy is Potentially Life-Changing for Adults with Hemophilia B
Perelman School of Medicine at the University of Pennsylvania

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the results of an international Phase III clinical trial published today in the New England Journal of Medicine by researchers from the University of Pennsylvania Perelman School of Medicine and a multicenter group of investigators.

Newswise: When a Child Hurts, Validating Their Pain May Be the Best First Aid
Released: 25-Sep-2024 4:30 PM EDT
When a Child Hurts, Validating Their Pain May Be the Best First Aid
University of South Australia

In a new study from the University of South Australia, researchers say that parents and doctors should be mindful of how they talk to and treat children experiencing pain – no matter how big or small the injury – knowing that these foundational experiences can be carried forward into adulthood.

Newswise: Unique Straining Affects Phase Transformations in Silicon, a Material Vital for Electronics
Released: 25-Sep-2024 4:05 PM EDT
Unique Straining Affects Phase Transformations in Silicon, a Material Vital for Electronics
Iowa State University

Iowa State's Valery Levitas and his collaborators have used pressure with a twisting shear to permanently deform silicon, an important material for electronics. The resulting changes in silicon's microstructure produce material phases that feature different and potentially useful properties.


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