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Bin Li’s research team from Shenyang Agricultural University highlights the potential of malvidin-3-O-galactoside (M3G), a blueberry-derived anthocyanin, to improve colonic mucosal barrier function and alleviate colitis symptoms.
Amid a crowded field of galaxies captured by NASA’s James Webb Space Telescope, one otherwise inconspicuous galaxy stands out for emitting a light signature that astronomers have never seen before. Together, an observational astronomer and a theorist investigated potential causes.
Researchers have discovered a new way to help liquid flow in only one direction, but without using the flaps that engines and our circulatory system rely upon to prevent fluid backup.
The development of versatile and efficient biocatalysts for the synthesis of α-hydroxyketones and Ephedra-type alkaloids represents a significant advancement in synthetic biology and medicinal chemistry. In this study, researchers explore the potential of acetolactate synthase (AlsS) from Bacillus subtilis (BsAlsS) for the production of phenylacetylcarbinol (PAC) and its derivatives. Additionally, the study investigates the use of intermediate reductive amination enzymes (introduction of amine group using enzymes) for functionalizing α-hydroxyketones to generate synthetic Ephedra-type alkaloids.
Researchers from China have achieved a breakthrough in biofuel production with the development of Rhodococcus aetherivorans strain N1, a new species, and its enhanced variant, N1-S. The study highlights how N1-S excels at detoxifying toxic byproducts from lignocellulosic biomass, resulting in a remarkable 6.5-fold increase in succinic acid yields compared to traditional methods.
Rutgers Health research finds the medications of grandparents and pets, as well as discarded items, pose unexpected hazards for young children.
This paper frames hardware-aware neural network pruning as a multi-objective optimization problem and introduces HAMP, a memetic Multi-Objective Evolutionary Algorithm (MOEA) that optimizes both accuracy and hardware efficiency through portfolio-based selection and surrogate-assisted local search.
Plant molecular farming (PMF) is an efficient strategy for producing recombinant protein. Tobacco plants, known for their short life cycle and large biomass production capacity, are excellent choices for PMF. In this review, researchers from institutes across China and Korea reviewed strategies for guiding recombinant proteins into different subcellular compartments of the cell. Findings reported in this review are extremely significant as optimized localization of recombinant proteins is crucial for pharmacological industries.
Coral reefs will continue to experience severe heat stress as rising temperatures cause the oceans to become unbearably hot – but a new study shows that altering their feeding habits could allow local populations to avoid total extinction.
A new review highlights the potential of CRISPR–Cas13 for RNA-editing therapies. Discussing the advantages of the effector protein Cas13 over Cas9, they report that CRISPR–Cas13 facilitates RNA knockdown, RNA silencing, RNA splicing, RNA-base editing, and translation regulation. CRISPR–Cas13 has diverse applications like virus detection, antivirus vaccines, and personalized therapies. Additionally, they also discuss the role of AI in enabling the realization of the full potential of RNA-editing technologies.
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