Mitochondria manufacture energy in every cell of the body, including heart muscle cells. A new study from Washington University School of Medicine in St. Louis shows that cardiac mitochondria are abnormal in the offspring of mouse mothers that become obese due to a high-fat, high sugar diet. Those offspring then pass on the mitochondrial defects at least two more generations.
There’s currently no good way to tell when – or even if – congenital heart defects will become apparent. Even defects that are identified and treated in childhood can resurface and cause problems in adulthood.
FINDINGS The menopause transition, also known as perimenopause, is the time in a woman’s life when hormonal changes lead to irregular menstruation, hot flashes and other symptoms leading up to menopause, when menstruation stops altogether. The researchers found that women undergoing perimenopause lost lean body mass and more than doubled their fat mass.
Age-related changes in our gut bacteria play a key role in making arteries stiff, degrading blood vessels and boosting risk of heart attack and stroke as we get older, according to a new, first-of-its kind study.
Irvine, Calif., March 19, 2019 — Bernadette Boden-Albala, Dr.P.H. – a renowned researcher and administrator whose efforts to reduce health disparities for America’s disadvantaged became a blueprint for community-based stroke and heart disease prevention – has been named director and founding dean of the University of California, Irvine’s planned School of Population Health, effective July 1.
The Valley Hospital participated in a landmark clinical trial that evaluated the ability of a novel, fully absorbable antibacterial envelope – the Medtronic TYRX™ Absorbable Antibacterial Envelope – to reduce infections associated with cardiac implantable electronic devices (CIEDs). The study found positive results and demonstrated that the envelope reduced the risk of major infection by 40 percent, and pocket infection by 61 percent, in patients at increased risk for infections receiving CIEDs, compared to standard-of-care pre-operative antibiotics.
Aging immigrants’ risk for cardiovascular disease may be heightened by their lack of health insurance, particularly among those who recently arrived in the United States, finds a study led by researchers at NYU Rory Meyers College of Nursing.
Diagnosis, treatments and outcomes for acute aortic dissection have evolved. An international registry (IRAD) reveals trends and the power of data, presented at the American College of Cardiology Scientific Session.
Currently, a practical, precise, minimally invasive way to measure cardiac output or heart function in children undergoing surgery does not exist. New research published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA), illustrates how a novel minimally invasive method using catheter-based ultrasound to measure heart function performed with similar precision to a traditional highly invasive device.
After the war is over, veterans face a new threat. They are more likely to have heart disease at a younger age than nonveterans, and this could herald a new health crisis on the horizon.
Stanley Chetcuti, M.D., co-author on the Evolut trial of low-risk TAVR/ interventional cardiologist at Michigan Medicine (University of Michigan) comments on importance of both late-breaking clinical trials re: low-risk TAVR (Evolut and Partner 3) at the American College of Cardiology Scientific Sessions.
In a new study from the Intermountain Healthcare Heart Institute in Salt Lake City, researchers have identified eight new gene mutations that may cause or contribute to idiopathic dilated cardiomyopathy, a form of heart disease not caused by known external influences, such as high blood pressure, obesity, smoking, or diseased coronary arteries.
A working group including Johns Hopkins Medicine cardiologists and American Heart Association (AHA) and American College of Cardiology (ACC) colleagues released updated guidelines for clinicians and patients on the primary prevention of cardiovascular disease. Primary prevention means the person doesn’t have any clinical symptoms yet, but the guidelines are designed to prevent a future first heart attack, stroke, heart failure and atrial fibrillation.
A Cleveland Clinic-led research team has found that using an absorbable, antibiotic-eluting envelope when implanting cardiac devices like pacemakers and defibrillators can cut the rate of major infections by 40 percent. The research was presented today at the American College of Cardiology’s 68th Annual Scientific Session and simultaneously published in the New England Journal of Medicine. It will also be presented tomorrow at the European Heart Rhythm Association 2019 Congress.
In a new study from the Intermountain Healthcare Heart Institute in Salt Lake City, researchers found that performing catheter ablations on patients who suffer from both atrial fibrillation and carotid arterial disease reduces the risk of dementia and stroke compared to managing their care with medications.
Any time a pregnant woman presents in heart failure there are risks to both mother and baby. What does it take to protect the mother and her growing baby for the best possible outcome?
A new research study presented at the American College Cardiology Scientific Sessions from the Intermountain Healthcare Heart Institute in Salt Lake City shows that identifying the presence or absence of coronary artery calcium (CAC) in a patients’ arteries can help determine their future risk.
The 33 million people with atrial fibrillation worldwide not only suffer from bothersome symptoms, but also face a fivefold increased risk of stroke and a twofold increased risk of death. Research teams led by Mayo Clinic published three connected studies on Friday, March 15, clarifying the benefits of catheter ablation versus rate- or rhythm-control medications to treat atrial fibrillation.
Atrial fibrillation is a common arrhythmia that affects an estimated 30 million people worldwide. New research shows that catheter ablation, a common cardiovascular procedure, appears no more effective than drug therapy to prevent strokes, deaths and other complications in patients with atrial fibrillation. But patients who receive catheter ablation experience much greater symptom relief and long-term improvements in quality of life. And they have fewer recurrences of their atrial fibrillation and fewer hospitalizations than those who receive only drugs. You can learn more about this new research in the March 15 issue of JAMA.
Research from the Cardiovascular Research Foundation (CRF) and the CRF Clinical Trials Center will be presented at the American College of Cardiology’s 68th Annual Scientific Session taking place March 16-18, 2019 at the Ernest N. Morial Convention Center in New Orleans, Louisiana. They will be presenting the latest data on percutaneous coronary intervention (PCI), imaging technologies, renal denervation, and transcatheter aortic valve replacement.
Atlantic Health System’s Morristown Medical Center, ranked one of the top 20 cardiology programs in the country by U.S. News & World Report, will be prominently featured at the American College of Cardiology’s 68th Annual Scientific Session, one of the premier meetings in the world for cardiology. The meeting will take place March 16-18 in New Orleans.
Three doctors will be presented with prestigious awards
Researchers have discovered an ingredient vital for proper blood vessel formation that explains why numerous promising treatments have failed. The discovery offers important direction for efforts to better treat a host of serious conditions ranging from diabetes to heart attacks and strokes.
Joe Janusz, president of the Peoria-area River City Bowling Association, is looking forward to bowling again following his heart transplant at Loyola University Medical Center. "When I throw that first ball, I will know I've completed my recovery," he said. "And I plan for it to be a strike."
After a heart attack, exosomes in the bloodstream carry greatly increased amounts of heart-specific microRNAs. The exosomes go to bone marrow progenitor cells, where the microRNAs turn off a gene that allows progenitor cells to leave the bone marrow and travel to the heart to attempt repairs.
The Detroit Cardiovascular Training Program at Wayne State University received notice that funding from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) will continue for the next five years with additional funding of $1.29 million. In addition, NIH has approved raising the trainee slots from four to six, strengthening the university’s ability to attract the most talented candidates searching for a cardiovascular graduate program.
The Cardiovascular Research Foundation (CRF) is pleased to announce that the latest issue of Structural Heart: The Journal of the Heart Team features original research articles on readmissions after atrial septal defect (ASD) closure and socioeconomic disparities in access to the Watchman device in patients with atrial fibrillation (AF).
Results could change treatment paradigms for the most devastating kind of ischemic stroke
The percentage of adults who have had a heart attack or have diabetes and regularly take statins — a medication used to lower cholesterol and reduce the risk for future cardiovascular events — has increased modestly in the United States. However, the percentage of adults who take statins regularly without a history of heart attack or diabetes has remained the same.
Eating a diet rich in fruits and vegetables, moderate in nuts, fish and alcohol and low in meat and full-fat dairy is associated with better cognitive performance in middle age, according to a study published in the March 6, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology. Cognitive abilities include thinking and memory skills.
New research suggests that young women with a family history of high blood pressure (hypertension) have decreased baroreflex function, which may increase their risk for hypertension later in life. The article, published ahead of print in the Journal of Neurophysiology (JNP), was chosen as an APSselect article for March.
Approximately 20 to 30 percent of adults in the United States may not be correctly diagnosed with having hypertension due to differences in their blood pressure when measured in their doctor’s office versus outside of their doctor’s office.
It may seem counterintuitive, but having some extra body fat may be linked to an increased chance of surviving a stroke, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 71st Annual Meeting in Philadelphia, May 4 to 10, 2019.
Robert H. Pass, MD, a nationally and internationally renowned pediatric cardiologist, has been appointed Division Chief of Pediatric Cardiology and Director of Pediatric Electrophysiology at the Mount Sinai Health System. He will also be Co- Director of the Children’s Heart Center.an alliance between the Mount Sinai Health System and Children's Hospital of Philadelphia, two world-leading institutions that provide an unprecedented scope of services for pediatric heart patients.
A computerized order set may help reduce the persistent problem of overmonitoring hospitalized patients. Appropriate monitoring increased after an order set was introduced into the EHR, prompting providers to order ECG monitoring per American Heart Association practice standards.
A calorie-dense, obesity-generating diet in aging mice disrupts the composition of the gut microbiome. This correlates with development of a system-wide nonresolving inflammation in acute heart failure, with a notable disruption of the immune cell profile, primarily the neutrophil-leukocyte ratio.
Researchers at the University of Illinois show that the membranes of cells surrounding arteries get stiffer and thicker in response to a high fat diet, due to both LDLs and oxidized LDLs
Researchers at the University of Colorado Boulder study fast-growing python hearts, which could provide insights to aid those with diseased heart growth. Their latest work reveals ways to study python heart cells.
Researchers at Imperial College London created a bioreactor to allow heart tissue to experience mechanical forces in sync with the beats, like it would in the body, to study the mechanics of healthy and diseased hearts.
Recent research suggests heart attacks are becoming more common among women of younger ages. For decades, little was understood about SCAD -- the leading cause of pregnancy-associated heart attacks.
When it comes to lifestyle changes that can help people avoid cancer, it turns out the heart has a lot to say on the matter.
Children’s Hospital Los Angeles (CHLA) recently performed its first dextrocardia heart transplant. The child, known as Baby Ruben, was born with dextrocardia and complex heterotaxy syndrome—including a single ventricle and discontinuous pulmonary arteries, along with other defects. The child received a heart transplant at CHLA at 2 years of age.
High blood pressure is among the most common medical conditions in the United States. It’s also among the most treatable.
Four generations of women, who all have the same hereditary condition – familial hypercholesterolemia – form a story interwoven with the discovery of new treatments that have benefited millions of people.
ARN President-Elect Barbara J. Lutz was honored with the Stroke Article of the Year Award.
Providing additional health-care services for heart failure patients to help them transition from hospital to home does not improve their outcome, according to research led by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences (HHS). The conclusion comes from a trial that followed the health status of almost 2,500 adults hospitalized for heart failure in hospitals across Ontario, Canada.
Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation.
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