Curated News: JAMA

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Newswise: Access matters: lack of resources is associated with increased mortality in childhood cancer survivors
8-Feb-2023 4:00 PM EST
Access matters: lack of resources is associated with increased mortality in childhood cancer survivors
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital researchers find increased risk of mortality in childhood cancer survivors is associated independently with local poverty, chronic conditions and frailty.

Released: 8-Feb-2023 3:35 PM EST
Complications in pregnancy linked to increased risk of heart disease
Lund University

Certain complications during pregnancy bring an increased risk of heart disease later on.

Newswise: Toddlers’ Attention to 'Motherese' Speech May Be Used to Diagnose Autism
6-Feb-2023 11:00 AM EST
Toddlers’ Attention to 'Motherese' Speech May Be Used to Diagnose Autism
University of California San Diego

Toddlers’ level of attention to "motherese" speech can be used as a biomarker for autism spectrum disorder (ASD). UC San Diego scientists developed a new eye-tracking test to measure it, which can accurately identify toddlers with a subtype of ASD.

Released: 8-Feb-2023 9:40 AM EST
VUMC’s ‘Shed-MEDS’ protocol can reduce risk of drug interactions in older people
Vanderbilt University Medical Center

An estimated one in six older adults in the United States who take multiple prescription drugs risk major drug-drug interactions and other adverse drug effects that can worsen their medical conditions, increase the likelihood of cognitive impairment and falls, and lead to hospitalization or death.

Released: 7-Feb-2023 4:05 PM EST
New biomarker for disease progression in multiple sclerosis
University of Basel

The autoimmune disease multiple sclerosis can take a variety of courses.

Newswise: Patient's satisfaction with doctor could influence decision to have bariatric surgery
Released: 7-Feb-2023 1:05 PM EST
Patient's satisfaction with doctor could influence decision to have bariatric surgery
UT Southwestern Medical Center

Patients’ satisfaction with their physicians may influence their decisions to undergo bariatric surgery, according to a multicenter study involving UT Southwestern and the UTHealth School of Public Health published in JAMA Network Open.

Newswise: Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
2-Feb-2023 11:05 AM EST
Early anti-VEGF treatment of diabetic retinopathy yields no benefit to visual acuity
NIH, National Eye Institute (NEI)

While early treatment of diabetes-related eye disease slowed progression to severe disease, it did not improve visual acuity compared with treating more severe disease once it developed, according to a clinical study from the DRCR Retina Network.

2-Feb-2023 1:00 PM EST
Spending on Consumer Advertising for Top-Selling Prescription Drugs in U.S. Favors Those With Low Added Benefit
Johns Hopkins Bloomberg School of Public Health

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that the share of promotional spending allocated to consumer advertising was on average 14.3 percentage points higher for drugs with low added benefit compared to drugs with high added benefit.

Released: 3-Feb-2023 7:30 PM EST
Kisspeptin hormone injection could treat low sex drive in women and men
Imperial College London

The hormone kisspeptin could be used to treat women and men distressed by their low sexual desire, according to two new studies.

   
1-Feb-2023 1:30 PM EST
Estimated Effectiveness of CoronaVac, Pfizer-BioNTech Vaccines Over Time Among Patients With SARS-CoV-2 Omicron
JAMA - Journal of the American Medical Association

Few studies have evaluated the waning of vaccine effectiveness against severe outcomes caused by SARS-CoV-2 Omicron infection. Hong Kong is providing inactivated and mRNA vaccines, but the population had limited protection from natural infections before the Omicron variant emerged.

Newswise: New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Released: 2-Feb-2023 1:10 PM EST
New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it. Their analysis, using a large national administrative database with records for pregnant people with SCD, found the maternal mortality rate was 26 times greater than the national average. This figure has not improved since the last time this population was assessed.

Released: 1-Feb-2023 12:05 PM EST
Academic medical centers are linked to better health outcomes at neighboring hospitals, researchers find
Beth Israel Deaconess Medical Center

A new study suggests that the presence of academic medical centers within a healthcare market is linked to better outcomes for patients treated at nearby community hospitals.

Newswise: New live bacterial product for stubborn superbug improves quality of life
Released: 31-Jan-2023 7:20 PM EST
New live bacterial product for stubborn superbug improves quality of life
University of Houston

Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).

Released: 25-Jan-2023 7:35 PM EST
People with additional X or Y chromosome at increased risk for dangerous blood clots
Geisinger Health System

People with an additional X or Y chromosome—a genetic condition known as supernumerary sex chromosome aneuploidy—have an increased risk of developing blood clots known as venous thromboembolism (VTE), a Geisinger study found.

Released: 24-Jan-2023 4:30 PM EST
Care Costs More in Consolidated Health Systems
Harvard Medical School

Nationwide study shows integrated health systems yield marginal increases in quality of care with higher costs for medical services, compared with care delivered by independent hospitals and physician practices. Proponents of health system mergers have argued that consolidation brings higher value care.

Newswise: Investigators Explore Impact of Cigarette Smoking and Alcohol Consumption on Black Breast Cancer Survivors
20-Jan-2023 3:30 PM EST
Investigators Explore Impact of Cigarette Smoking and Alcohol Consumption on Black Breast Cancer Survivors
Rutgers Cancer Institute of New Jersey

In a new study published by JAMA Network Open, Dr. Elisa Bandera, Dr. Nur Zeinomar from Rutgers Cancer Institute of New Jersey and colleagues found that a higher risk of mortality in Black breast cancer survivors is associated with a history of cigarette smoking along with regular alcohol consumption at the time of diagnosis.

Released: 23-Jan-2023 5:05 PM EST
Coordination of COVID-19 Vaccine Clinical Trials Produces a ‘Treasure Trove’ of Data and a Model for the Future
Covid-19 Prevention Network (CoVPN)

The federally funded COVID-19 Prevention Network was instrumental in the rapid development of safe, effective and lifesaving COVID-19 vaccines during earlier phases of the pandemic. This vital work to expedite Phase 3 clinical trials also resulted in a 'treasure trove' of data, thanks to a highly collaborative and harmonized approach that can serve as a national and even international model for major research initiatives while also guiding responses to future public health emergencies.

Released: 23-Jan-2023 1:05 PM EST
Head Injury is Associated with Doubled Mortality Rate Long-Term, Penn Study Finds
Perelman School of Medicine at the University of Pennsylvania

A new study reveals adults who suffered any head injury during a 30-year study period had two times the rate of mortality than those who did not have any head injury, and mortality rates among those with moderate or severe head injuries were nearly three times higher.

Released: 20-Jan-2023 6:55 PM EST
Across the US, white neighborhoods have more greenery, fewer dilapidated buildings, fewer multi-family homes
Boston University School of Public Health

Historic redlining and other racist policies have led to present-day racial and economic segregation and disinvestment in many cities across the United States.

   
Released: 20-Jan-2023 5:50 PM EST
Overdose deaths involving buprenorphine did not proportionally increase with new flexibilities in prescribing
NIH National Institute on Drug Abuse (NIDA)

The proportion of opioid overdose deaths involving buprenorphine, a medication used to treat opioid use disorder, did not increase in the months after prescribing flexibilities were put in place during the COVID-19 pandemic, according to a new study.

Released: 20-Jan-2023 5:25 PM EST
Rest isn’t best: Getting kids back to school sooner after a concussion can mean a faster recovery
Children's National Hospital

Contrary to popular belief, rest may not always be the best cure after a concussion, new study published in JAMA Network Open finds.

Newswise: Suicide Risk Higher Among Individuals with Cancer, New Study Shows
18-Jan-2023 11:05 AM EST
Suicide Risk Higher Among Individuals with Cancer, New Study Shows
American Cancer Society (ACS)

According to a new large study led by researchers at the American Cancer Society, the risk of suicide for individuals diagnosed with cancer in the United States is 26% higher compared with the general population.

Newswise: Study: Social Needs Intervention Research Lacking in Race and Ethnicity Analyses
Released: 19-Jan-2023 3:50 PM EST
Study: Social Needs Intervention Research Lacking in Race and Ethnicity Analyses
UC San Diego Health

A new paper published in the Jan. 19, 2023, online edition of JAMA Network Open looks at how social needs intervention research recognizes race and ethnicity, which according to the study authors, are social, not biological concepts.

   
Released: 18-Jan-2023 7:15 PM EST
COVID-19 symptoms 6 months after onset, role of vaccination for SARS-CoV-2 infection
JAMA - Journal of the American Medical Association

In this study of 1,832 U.S. adults, the risk of reporting symptoms for 28 or more days after COVID-19 onset was significantly higher in participants who were unvaccinated at the time of infection and those who reported moderate or severe acute illness symptoms.

Released: 18-Jan-2023 5:55 PM EST
Delayed appendicitis diagnosis more common among non-Hispanic Black adults
Northwestern University

Non-Hispanic Black adults more frequently experience delays in receiving an appendicitis diagnosis in hospital emergency departments, putting them at a higher likelihood of perforated appendicitis and subsequent post-surgical infections, reports a new Northwestern Medicine study.

Newswise: Quality of treatment for lung cancer varies widely across US
17-Jan-2023 3:40 PM EST
Quality of treatment for lung cancer varies widely across US
Washington University in St. Louis

A new study by researchers at Washington University School of Medicine in St. Louis found that the quality of care for lung cancer in the U.S. varies widely. The findings show that high-quality care is associated with improved overall survival rates among patients with lung cancer.

11-Jan-2023 9:50 AM EST
Machine Learning-Triggered Reminders Improve End-of-Life Care for Patients with Cancer
Perelman School of Medicine at the University of Pennsylvania

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

10-Jan-2023 12:00 PM EST
MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer
University of California, Los Angeles (UCLA), Health Sciences

For men who undergo radiotherapy for localized prostate cancer, the precise targeting capabilities of MRI guidance resulted in fewer toxicities and better quality of life according to new research from UCLA Jonsson Comprehensive Cancer Center.

Released: 11-Jan-2023 9:50 AM EST
Medicare policy change could increase inequity in heart transplant access, study finds
Michigan Medicine - University of Michigan

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a new study finds. Results reveal that patients receiving Left Ventricular Assist Devices at transplant-capable centers had 79% higher odds to receive a bridge-to-transplant designation than patients treated at LVAD-only centers.

Released: 10-Jan-2023 5:55 PM EST
Perceptions of stress, mood associated with listening to music during COVID-19 lockdown
JAMA - Journal of the American Medical Association

Listening to music in daily life was significantly associated with lower levels of stress during the COVID-19 lockdown period in this study of 711 adults.

9-Jan-2023 3:40 PM EST
School garden-based interventions can improve blood sugar, reduce bad cholesterol in children
University of Texas Health Science Center at Houston

School garden-based interventions can improve metabolic parameters such as blood sugar and cholesterol in children, according to a new study from UTHealth Houston.

Released: 6-Jan-2023 5:20 PM EST
Study suggests one solution to America’s opioid epidemic: Tell doctors their patients fatally overdosed
University of Southern California (USC)

There are no simple solutions to America’s deadly overdose epidemic, which costs 100,000 lives each year and is erasing gains in life expectancy.

6-Jan-2023 9:55 AM EST
Nearly 1/3 of people with chronic pain turn to cannabis
Michigan Medicine - University of Michigan

According to a new study published in JAMA Network Open, almost a third of patients with chronic pain reported using cannabis to manage it.

Newswise: Roswell Park Study: Chronic Opioid Use Reduced by Limiting Prescribed Opioids After Surgery
Released: 5-Jan-2023 2:30 PM EST
Roswell Park Study: Chronic Opioid Use Reduced by Limiting Prescribed Opioids After Surgery
Roswell Park Comprehensive Cancer Center

Research at Roswell Park Comprehensive Cancer Center shows that putting a three-day limit on opioid prescriptions to treat surgical pain after hospital discharge reduces the number of patients who become chronic opioid users without compromising pain relief or recovery. It also reduces the amount of opioids circulating in the community — a grave concern, given that opioids are implicated in 130 overdose deaths in the U.S. every day.

Released: 4-Jan-2023 8:45 AM EST
Study Finds Climate Impact Labels on Sample Fast Food Menu Had Strong Effect on Food Selection
Johns Hopkins Bloomberg School of Public Health

A new study has found that including climate impact labels on a sample fast food menu influenced participants’ food choices in favor of more climate-friendly items. The study was led by a researcher at the Johns Hopkins Bloomberg School of Public Health.

   
Released: 3-Jan-2023 4:10 PM EST
Examination of COVID-19 vaccine reactions after multisystem inflammatory syndrome in children
JAMA - Journal of the American Medical Association

In this study of study of 385 patients ages 5 or older with a history of multisystem inflammatory syndrome in children (MIS-C), no serious adverse events were reported after COVID-19 vaccination.

Newswise: When Doctors Know Each Other
28-Dec-2022 11:00 AM EST
When Doctors Know Each Other
Harvard Medical School

Patients under the care of specialists who trained with the patients’ primary care physicians (PCPs) reported being treated with a more concerned manner, receiving clearer explanations, and experiencing greater engagement in shared decision-making, among other benefits, the study found.

Newswise: December Research Highlights
Released: 29-Dec-2022 5:45 PM EST
December Research Highlights
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

Released: 28-Dec-2022 7:40 PM EST
Restricted abortion access linked to increased suicide risk in young women
University of Pennsylvania

When the Dobbs v. Jackson Supreme Court decision came down in June, overturning the right to abortion in the United States that Roe v. Wade had bestowed in 1973, conversations about access to reproductive care took on a renewed urgency.

Released: 28-Dec-2022 7:35 PM EST
Assessment of mental health services available through smartphone apps
JAMA - Journal of the American Medical Association

In this study of 578 mental health apps, findings indicate that the current app marketplaces primarily offered basic features such as psychoeducation, goal tracking, and mindfulness but fewer innovative features such as biofeedback or specialized therapies.

   
Released: 27-Dec-2022 7:00 PM EST
Health care is increasingly unaffordable for people with employer-sponsored health insurance—especially women
New York University

Health care is growing less affordable for U.S. adults—particularly women—with employer-sponsored health insurance, according to an analysis by researchers at the NYU School of Global Public Health published in the Journal of the American Medical Association (JAMA).

Released: 22-Dec-2022 7:40 PM EST
In some US zip codes, young men face more risk of firearm death than those deployed in recent wars
Brown University

The risk of firearm death in the U.S. is on the rise: in 2020, firearms became the leading cause of death for children, adolescents and young adults. Yet the risk is far from even — young men in some U.S. zip codes face disproportionately higher risks of firearm-related injuries and deaths.

Released: 22-Dec-2022 7:25 PM EST
Randomized trial finds therapies for spine pain improved disability and quality of life but did not decrease healthcare spending
Brigham and Women’s Hospital

Pain in the back or the neck is extremely common and accounts for more healthcare spending than any other health condition.

Newswise: Mediterranean Diet Linked to Lower Preeclampsia Risk
Released: 22-Dec-2022 2:25 PM EST
Mediterranean Diet Linked to Lower Preeclampsia Risk
Cedars-Sinai

In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy.



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