Hackensack Meridian Hackensack University Medical Center’s Department of Urology presented 14 abstracts at the American Urological Association’s (AUA) 2023 Annual Meeting.
A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research published in The New England Journal of Medicine and led by an oncologist from Dana-Farber Cancer Institute.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
In medicine and science, the term “pathogenesis” describes the origin and development of disease. There is not, however, a broadly accepted term to describe the other half of the equation: the process of healing and recovery.
For patients with kidney stones measuring one to two centimeters, a technique called mini-percutaneous nephrolithotomy (mini-PCNL) provides a higher stone elimination rate than another minimally invasive procedure called ureteroscopy (URS), concludes a randomized trial in the June issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Acute kidney injury (AKI) represents a major morbidity following cardiac surgery; and, when moderate or severe, it is strongly associated with postoperative mortality. Approximately one-third of adults and up to half of all children who undergo cardiac surgery develop some degree of postoperative AKI.
Sian Piret, PhD, in the Renaissance School of Medicine at Stony Brook University, has received a $1.4 million grant from the National Institute of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to investigate a certain metabolic process called BCAA catabolism that is known to occur with acute kidney injury, but its exact role remains unknown.
Upon an arrival to the emergency department for abdominal pain of unknown cause, most non-pregnant adult patients receive a CT scan with IV contrast to diagnose the source of the pain. However, IV contrast can be a risk in patients with severe kidney disease or at risk for an allergic reaction from the dye. When scans are performed without IV contrast, though, they are usually less accurate, which can lead to misdiagnosis.
For millions of Americans that suffer from seasonal allergies (pollen and mold), climate change is exacerbating an earlier, longer, and overall worse allergy season.
Researchers at Children’s Hospital Los Angeles have now pinpointed a disruption in early kidney progenitor cell development that can be linked to the formation of Wilms tumor.
• The Living Donor Protection Act (LDPA) will remove barriers facing living donors. • Approximately 90,000 adults and 1,100 children are on the kidney transplant waitlist. • 12 American die every day while waiting for a kidney transplant. • More than 37 million Americans are living with kidney diseases, including more than 800,000 with kidney failure.
Experts from the Cedars-Sinai Comprehensive Transplant Center and Smidt Heart Institute are available for interviews about transplantation, immunology and organ donation in April, Donate Life Month, and throughout the year.
Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center and the Department of Urology at the David Geffen School of Medicine at UCLA will be joining thousands of urology experts on April 28 to May 1 for the American Urological Association (AUA) Annual Meeting.
Hackensack University Medical Center is the first hospital in the country to invest in the new LithoVue™ Elite Single-Use Digital Flexible Ureteroscope System, and one of the first U.S. hospitals to use this next-generation system, which has the ability to monitor intrarenal pressure in real-time during ureteroscopy procedures.
Little is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors. But a study out of Roswell Park Comprehensive Cancer Center is shedding light on that process, providing information that could be key for planning treatment regimens that combine immunotherapy and radiation therapy. The authors outline their findings in a new study in the Journal for ImmunoTherapy of Cancer.
In a study conducted at Hospital for Special Surgery (HSS), researchers found that the use of peripheral nerve blocks in total knee and total hip arthroplasty were associated with a consistent reduction in risk for postoperative complications in patients with a lower comorbidity burden. In particular, the most consistent reduction in risk of complications and use of hospital resources was in older patients with no comorbidity burden. These findings were presented at the 2023 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting and were acknowledged as one of the President’s Choice Abstracts.1
Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.
New research results suggest that the widely used diabetes drug metformin may be beneficial for recovering from short periods of severe food insecurity or anorexia.
MaryAshley Barbot waited 10 years for a new kidney, but the hospitals near her South Carolina home were unable to find a match. Now, the teenager is in the best health of her life, six months after receiving a kidney transplant at Cedars-Sinai.
Members of the House of Representatives Committee on Energy and Commerce signaled support for the Securing the U.S. Organ Procurement and Transplantation Network Act (SUS OPTN) during the Energy and Commerce Health Subcommittee Hearing on Existing Healthcare Workforce and Primary Care Programs.
Vijay Goradia, a Houston-based businessman, philanthropist, and cancer survivor, has donated $10 million to The University of Texas MD Anderson Cancer Center to speed translational research and clinical trials.
Since the Spanish Language Clinic began in April 2022, more than 160 patients have signed up with the clinic, which specifically treats Spanish-speaking patients on Tuesdays and Fridays, said Samantha Mok, transplant outreach coordinator at UI Health.
In a new study, researchers from The University of Texas MD Anderson Cancer Center created the largest single-cell atlas of brain metastases from renal cell carcinoma (RCC) with matched primary and extracranial metastases, enabling the discovery of key biological mechanisms driving an immunosuppressive tumor microenvironment in the brain distinct from that of the kidney or other metastatic sites.
The CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouraging response rates and disease control rates in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to results of a Phase I trial led by researchers at The University of Texas MD Anderson Cancer Center and presented today at the American Association for Cancer Research (AACR) Annual Meeting 2023.
A new Japanese study reveals significant birth cohort effects on the incidence trend of ESKD requiring RRT.
The National Comprehensive Cancer Network (NCCN) and the NCCN Foundation announce four winners for the 2023 NCCN Foundation Young Investigator Awards. These annual awards honor up-and-coming leaders in oncology research working to investigate and advance cancer care.
Researchers at the University of Bristol have made a breakthrough that could prevent certain kidney patients progressing towards renal failure.
Below are some of the latest headlines in the new Avian Flu channel on Newswise.
Susan Hedayati, M.D., Director of Clinical and Population Health Research in Nephrology at UT Southwestern, has spent a career investigating the links between kidney disease and depression and developing methods to improve care from a patient-centric perspective for those with chronic kidney disease.
New research from RUSH University reveals pathways to reducing organ injury caused by severe COVID-19 infection. What began as a study of how the common cold affected patients with certain types of kidney disease evolved to mitigating myocarditis, liver injury and severe kidney injury from COVID-19.
An international study shows that it is likely that insulin can be stored at room temperature, and for considerably longer than drug companies have counted on to date. Access to this vital medicine can thereby be significantly improved for the world’s poorest inhabitants. Researchers at the University of Gothenburg are among the scientists presenting these results.
The American Society of Nephrology (ASN) applauds the introduction of the Securing the U.S. Organ Procurement and Transplantation Network Act, bipartisan legislation to ensure accountability and transparency in the U.S. transplant system by modernizing its underlying technology and policy infrastructure.
“I’ve been riding my bike all over the country to showcase how healthy and active a living organ donor can be after donation,” said Scotch. “Today, in New Orleans, I had the unique opportunity to add a tugboat ride on the great Mississippi to my journey to make it that much more remarkable. Ending my day by raising the flag at Ochsner’s Transplant Institute was a fitting end to the day to celebrate the work they are doing with transplant donations to save lives.”
The American Society of Nephrology (ASN) introduces six new recipients of its Loan Mitigation Pilot Program, which provides $50,000 in financial support for trainees entering the field of nephrology.
The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.
More than 100,000 people in the U.S. are awaiting new organs. Many won’t live long enough to get them. The new chief of transplant at Penn State Health Milton S. Hershey Medical Center debunks the myths that get between donors and recipients.
Chronic kidney disease is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. A new risk model for cardiovascular disease, developed by Penn, was found to be more accurate than existing clinical models.
In a new study looking at the long-term effects of hospitalized patients who have acute kidney injury (AKI), a sudden but temporary loss of kidney function, Johns Hopkins Medicine researchers found that higher levels of certain biomarkers in urine and blood can predict a patient’s risk of developing chronic kidney disease (CKD).
In this study led by Dana-Farber Cancer Institute, interim results of the combination of cabozantinib, a VEGF TKI, plus belzutifan, a HIF-2α inhibitor, show promising anti-tumor activity in this pre-treated patient group. The results suggest that the combination might fill and unmet need and provides a rationale for further study of combining a VEGF TKI and a HIF-2 inhibitor.
The kidney plays a vital role in maintaining homeostasis within the body by eliminating toxic and superfluous substances in the bloodstream, including waste generated during metabolic processes, through urine.
High blood pressure in children is not uncommon, and research shows it may lead to high blood pressure in adulthood, as well as problems with the heart, blood vessels and kidneys.
Housed at the University of Chicago Medicine, the Bridging the Gap: Reducing Disparities in Diabetes Care Initiative has published the results of their five-year project aimed at addressing disparities in diabetes care nationwide.
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