New research shines a light on specific cell types that drive normal or diseased kidney function at the molecular level.
All children have moments of moodiness, but family medicine doctors and pediatricians may doubt their abilities to tell the difference between normal irritability and possibly bigger issues, according to Penn State researchers.
Study finds elderly hip fracture patients have better survival rates with regional than general anesthesia during surgery,
Use of 2 or more different classes of nonopioid analgesic medications in the interoperative period associated with reduction in postoperative pain.
Regional anesthesia was shown to be superior to local anesthesia in study of dialysis patients
Spinal anesthesia was associated with lower risk of mortality compared to general anesthesia in a group of elderly hip fracture patients.
Pulsed wave Doppler (PWD) shows potential as a marker to verify catheter tip location in patients receiving peripheral nerve and epidural catheters for surgery.
The University of Pennsylvania Health System, Mercy Health System of Southeastern Pennsylvania (Mercy) and St. Mary Medical Center (St. Mary) have announced an alliance to focus on the development of joint clinical care programs and population health initiatives to improve health care throughout the Greater Philadelphia region.
Rats who were dosed with nicotine during their adolescence grew up to drink alcohol more often than those who weren’t exposed to nicotine or were only exposed to it during adulthood. Exposure to nicotine at a young age changed the neuronal circuitry in the rat brain’s reward pathways
There are many factors that determine your likelihood of developing cancer, including age, genetic predisposition and lifestyle.
Marylyn D. Ritchie, PhD, a nationally regarded geneticist and expert in using big data and machine-learning methods to improve human health, has been appointed as director, Center for Translational Bioinformatics, Institute for Biomedical Informatics (IBI) in the Perelman School of Medicine at the University of Pennsylvania
For children with severe cerebral palsy (CP), surgery for scoliosis (sideways curvature of the spine) significantly improves the quality of life (QoL) for them and their caregivers, reports a study in the April 4, 2018, issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
NCCN announces 2018 Young Investigator Awards: Rebecca Arend, MD, UAB Comp. Cancer Ctr; Yin Cao, MPH, ScD, Siteman Cancer Ctr at Barnes-Jewish Hospital and Washington U. Sch of Medicine; Tim Luetkens, MD, Huntsman Cancer Inst. at the U. of Utah; Edwin R. Manuel, PhD, City of Hope; and Cecilia Yeung, MD, Fred Hutchinson Cancer Research Ctr, Seattle Cancer Care Alliance.
What steps can employers take to reduce the high costs and health impact of mental health issues? An expert Advisory Council has developed a set of recommendations for improving mental health and well-being in the workplace, according to a report in the April Journal of Occupational and Environmental Medicine.
Patient safety is the focus of newly published updates to consensus statements that address the use of antithrombotic drugs by individuals who may require regional anesthesia or interventions targeting acute or chronic pain.
A group of Penn researchers hopes to improve the understanding of these present-day ailments by looking at the very engine of evolution: natural selection in humans.
The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers.
Penn State College of Medicine has created a new Department of Radiation Oncology and named Dr. Rickhesvar Mahraj, professor of radiology and pediatrics, its interim chair.
Patients treated for heart attack were 48 percent less likely to have a sudden return to the hospital when educated using a multi-factored discharge and follow-up program
Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis. The study, published today in Oncogene, represents significant progress in the clinical translation of previous basic scientific discoveries.
E. John Wherry, PhD, co-leader of the Abramson Cancer Center’s Immunobiology Program and director of the Institute for Immunology at the University of Pennsylvania, has received a Phillip A. Sharp Innovation in Collaboration Award from Stand Up To Cancer.
Every day, about 165 in-flight emergencies occur on the 100,000 or so airplanes that take to the skies around the world, according to the most recent estimates. But, there are currently no federal guidelines for physicians in these situations, and there is no mandatory reporting system that tracks in-flight emergencies. After being the only physician on board during two in-flight emergencies, Rachel Zang, MD, an Emergency Medicine resident at the Hospital of the University of Pennsylvania, learned as much as she could about the laws and what exactly is in on-board medical kits. Today she imparts that knowledge to other physicians.
A slippery rough surface (SRS) inspired by both pitcher plants and rice leaves outperforms state-of-the-art liquid-repellent surfaces in water harvesting applications, according to a team of researchers at Penn State and University of Texas at Dallas.
PHILADELPHIA – The Hospital of the University of Pennsylvania, Pennsylvania Hospital, Penn Presbyterian Medical Center, and Chester County Hospital were announced among the 2018 class of the Human Rights Campaign (HRC) Foundation’s The HRC Foundation is the educational arm of the country’s largest lesbian, gay, bisexual and transgender (LGBT) civil rights organization.
Patients traveling to developing countries for plastic surgery procedures may experience severe complications—requiring extensive and costly treatment after they return to the United States, reports a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Breast augmentation with implants does not interfere with the ability to detect later breast cancers—in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
NCCN presented awards during the NCCN 23rd Annual Conference to Crystal Denlinger, MD, Abdul-Rahman Jazieh, MD, MPH, Warren Smedley, MSHA, Ronald Walters, MD, MBA, MHA, MS, and Kristin Kline Hasson.
It’s not unusual for your body to make “popping” or “cracking” sounds as you lean over, twist or reach for something. Fortunately, it’s also typically not a cause for worry.
In response to repeated calls for an integrated emergency care system in the U.S., the University of Pittsburgh rose to the challenge and divided the nation into hundreds of referral regions that describe how patients access advanced care, in a way that respects geopolitical borders.
A distinguished molecular virologist will lead the University of Pittsburgh’s Center for Vaccine Research, which focuses on the development of diagnostics, therapeutics and vaccines for infectious diseases that pose risks to global public health.
Mental health symptoms related to attention deficit-hyperactivity disorder (ADHD) and conduct disorder are associated with increased errors in a driving simulator and self-reported risky driving behaviors in adolescents, according to study in Nursing Research, published by Wolters Kluwer.
Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.
A systematic study of seven antioxidants commonly taken by or suggested to benefit children and adults affected with mitochondrial disease provides intriguing clues that at least two compounds should be further evaluated in clinical trials. There are currently no proven, effective treatments for mitochondrial disease.
The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to Penn State College of Medicine researchers.
Optimizing the timing of targeted therapies for melanoma reverses tumor growth, and resistance can be mitigated.
Wistar and YourEncore, Inc., a life sciences and consumer goods consulting company engaging highly experienced, top talent industry experts, have signed a Memorandum of Understanding (MoU) to help accelerate the advancement of Wistar's early-stage discoveries, start-ups and international collaborations.
Temple has supported 43,000 jobs statewide and generated more than $205 million in tax revenue for the Commonwealth of Pennsylvania.
Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells. The specific disease mechanism has not previously been implicated in a human disease.
As more patients undergo total hip arthroplasty (THA) before age 65, the rate of repeat hip surgery due to complications has risen sharply in this younger age group, reports a study in the March 21, 2018, issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
A well-studied enzyme called SIRT1 declines in the blood vessels with age and restoring it reverses the effects of vascular aging in mice. After receiving a supplement called NMN, older mice showed increased capillary density, blood flow, mobility, and endurance
As the winter cold season melts into seasonal spring allergies, many people may start to experience sneezing, wheezing and other breathing difficulties. Sometimes, the trouble goes away after a few days, but if it lingers or recurs, asthma could be the culprit.
The most common gene mutation associated with Parkinson’s alters cells circulating outside the brain, not within, offering a new understanding of what causes the disease.
Researchers from Penn State, China and Australia have developed a material with twice the piezo response of any existing commercial ferroelectric ceramics.
A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.
Patients who have been taking opioid pain relievers for several months before spinal fusion surgery are at increased risk of complications after their surgery, reports a study in the journal Spine, published by Wolters Kluwer.
Researchers have discovered a “missing mutation” in severe infant epilepsy—long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures. They also found early indications that specific anti-seizure medications might prevent disabling brain injury.
Limiting first-year medical residents to 16-hour work shifts, compared to “flexing” them to allow for some longer shifts, generally makes residents more satisfied with their training and work-life balance, but their training directors more dissatisfied with curtailed educational opportunities. That’s one conclusion of a new study published online March 20 in the New England Journal of Medicine.
Increasing the availability of effective pain management in low- to middle-income countries will be an essential part of ongoing efforts to expand global access to safe surgery and anesthesia, according to a special article in the April issue of Anesthesia & Analgesia.
Moral philosophers are in agreement that shame is a natural and valuable emotion that occurs most often when someone does not live up to their ideals or standards.
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