New research shines a light on specific cell types that drive normal or diseased kidney function at the molecular level.
The University of Pennsylvania Health System, Mercy Health System of Southeastern Pennsylvania (Mercy) and St. Mary Medical Center (St. Mary) have announced an alliance to focus on the development of joint clinical care programs and population health initiatives to improve health care throughout the Greater Philadelphia region.
Rats who were dosed with nicotine during their adolescence grew up to drink alcohol more often than those who weren’t exposed to nicotine or were only exposed to it during adulthood. Exposure to nicotine at a young age changed the neuronal circuitry in the rat brain’s reward pathways
Marylyn D. Ritchie, PhD, a nationally regarded geneticist and expert in using big data and machine-learning methods to improve human health, has been appointed as director, Center for Translational Bioinformatics, Institute for Biomedical Informatics (IBI) in the Perelman School of Medicine at the University of Pennsylvania
For children with severe cerebral palsy (CP), surgery for scoliosis (sideways curvature of the spine) significantly improves the quality of life (QoL) for them and their caregivers, reports a study in the April 4, 2018, issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
NCCN announces 2018 Young Investigator Awards: Rebecca Arend, MD, UAB Comp. Cancer Ctr; Yin Cao, MPH, ScD, Siteman Cancer Ctr at Barnes-Jewish Hospital and Washington U. Sch of Medicine; Tim Luetkens, MD, Huntsman Cancer Inst. at the U. of Utah; Edwin R. Manuel, PhD, City of Hope; and Cecilia Yeung, MD, Fred Hutchinson Cancer Research Ctr, Seattle Cancer Care Alliance.
What steps can employers take to reduce the high costs and health impact of mental health issues? An expert Advisory Council has developed a set of recommendations for improving mental health and well-being in the workplace, according to a report in the April Journal of Occupational and Environmental Medicine.
A group of Penn researchers hopes to improve the understanding of these present-day ailments by looking at the very engine of evolution: natural selection in humans.
The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat cancers.
Patients treated for heart attack were 48 percent less likely to have a sudden return to the hospital when educated using a multi-factored discharge and follow-up program
Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis. The study, published today in Oncogene, represents significant progress in the clinical translation of previous basic scientific discoveries.
E. John Wherry, PhD, co-leader of the Abramson Cancer Center’s Immunobiology Program and director of the Institute for Immunology at the University of Pennsylvania, has received a Phillip A. Sharp Innovation in Collaboration Award from Stand Up To Cancer.
Every day, about 165 in-flight emergencies occur on the 100,000 or so airplanes that take to the skies around the world, according to the most recent estimates. But, there are currently no federal guidelines for physicians in these situations, and there is no mandatory reporting system that tracks in-flight emergencies. After being the only physician on board during two in-flight emergencies, Rachel Zang, MD, an Emergency Medicine resident at the Hospital of the University of Pennsylvania, learned as much as she could about the laws and what exactly is in on-board medical kits. Today she imparts that knowledge to other physicians.
PHILADELPHIA – The Hospital of the University of Pennsylvania, Pennsylvania Hospital, Penn Presbyterian Medical Center, and Chester County Hospital were announced among the 2018 class of the Human Rights Campaign (HRC) Foundation’s The HRC Foundation is the educational arm of the country’s largest lesbian, gay, bisexual and transgender (LGBT) civil rights organization.
Patients traveling to developing countries for plastic surgery procedures may experience severe complications—requiring extensive and costly treatment after they return to the United States, reports a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Breast augmentation with implants does not interfere with the ability to detect later breast cancers—in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
NCCN presented awards during the NCCN 23rd Annual Conference to Crystal Denlinger, MD, Abdul-Rahman Jazieh, MD, MPH, Warren Smedley, MSHA, Ronald Walters, MD, MBA, MHA, MS, and Kristin Kline Hasson.
Mental health symptoms related to attention deficit-hyperactivity disorder (ADHD) and conduct disorder are associated with increased errors in a driving simulator and self-reported risky driving behaviors in adolescents, according to study in Nursing Research, published by Wolters Kluwer.
Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.
A systematic study of seven antioxidants commonly taken by or suggested to benefit children and adults affected with mitochondrial disease provides intriguing clues that at least two compounds should be further evaluated in clinical trials. There are currently no proven, effective treatments for mitochondrial disease.
Optimizing the timing of targeted therapies for melanoma reverses tumor growth, and resistance can be mitigated.
Wistar and YourEncore, Inc., a life sciences and consumer goods consulting company engaging highly experienced, top talent industry experts, have signed a Memorandum of Understanding (MoU) to help accelerate the advancement of Wistar's early-stage discoveries, start-ups and international collaborations.
Temple has supported 43,000 jobs statewide and generated more than $205 million in tax revenue for the Commonwealth of Pennsylvania.
Neurology researchers investigating a rare but devastating neurological regression in infants have discovered the cause: gene mutations that severely disrupt crucial functions in mitochondria, the energy-producing structures within cells. The specific disease mechanism has not previously been implicated in a human disease.
As more patients undergo total hip arthroplasty (THA) before age 65, the rate of repeat hip surgery due to complications has risen sharply in this younger age group, reports a study in the March 21, 2018, issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
A well-studied enzyme called SIRT1 declines in the blood vessels with age and restoring it reverses the effects of vascular aging in mice. After receiving a supplement called NMN, older mice showed increased capillary density, blood flow, mobility, and endurance
The most common gene mutation associated with Parkinson’s alters cells circulating outside the brain, not within, offering a new understanding of what causes the disease.
A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.
Patients who have been taking opioid pain relievers for several months before spinal fusion surgery are at increased risk of complications after their surgery, reports a study in the journal Spine, published by Wolters Kluwer.
Researchers have discovered a “missing mutation” in severe infant epilepsy—long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures. They also found early indications that specific anti-seizure medications might prevent disabling brain injury.
Limiting first-year medical residents to 16-hour work shifts, compared to “flexing” them to allow for some longer shifts, generally makes residents more satisfied with their training and work-life balance, but their training directors more dissatisfied with curtailed educational opportunities. That’s one conclusion of a new study published online March 20 in the New England Journal of Medicine.
Increasing the availability of effective pain management in low- to middle-income countries will be an essential part of ongoing efforts to expand global access to safe surgery and anesthesia, according to a special article in the April issue of Anesthesia & Analgesia.
Moral philosophers are in agreement that shame is a natural and valuable emotion that occurs most often when someone does not live up to their ideals or standards.
The University of Pennsylvania School of Nursing (Penn Nursing) is again the number one nursing school in the world according to a recent ranking by QS World University. The rankings highlight the world’s top universities in 48 different subject areas (as of 2018) based on academic reputation, employer reputation, and research impact. This is the third consecutive year that Penn Nursing has taken the top spot.
About five percent of older adults on Medicare don't have a "personal physician," and this group scores lower on measures of healthcare quality, reports a study in the April issue of Medical Care, published by Wolters Kluwer.
Cities experienced 2.3 more assaults than average on days when hosting presidential campaign rallies for Donald Trump during the lead-up to the 2016 United States Presidential Election, according to a first of its kind study published online today in Epidemiology by researchers in the Perelman School of Medicine at the University of Pennsylvania. Hillary Clinton rallies were not linked to any increase in assaults.
While there has been an increased focus on person-centered models of care transition for cognitively intact older adults from hospital to home, little is known about the core elements of successful transitions in care specifically for persons with dementia.
Physician-researchers from the Cardiac Center at Children’s Hospital of Philadelphia (CHOP) presented new findings on pediatric cardiovascular disease at the American College of Cardiology’s 67th Annual Scientific Session & Expo 2018 in Orlando, Fla. Among many abstracts presented were emergency department visits in patients with congenital heart disease, social risk factors for readmission, factors predicting mortality after prolonged critical illness and more.
Charles Library, to open next year, will carry the name of the trustee and philanthropist.
While cervical cancer – one of the most common cancers in women – has significantly decreased in the United States, it is still the second most common cancer in women who live in less developed countries, according to the World Health Organization. Women in sub-Saharan Africa (SSA) have the largest age-standardized incidence and mortality rates of this potentially preventable and non-communicable disease due to the difficulty in implementing prevention, screening, and treatment programs
Charles Library, to open next year, will carry the name of the trustee and philanthropist.
"Has this patient been drinking?" It's a critical question for neurosurgical nurses and other professionals when evaluating patients with traumatic brain injury (TBI). But some groups of TBI patients are less likely to be screened for alcohol use, including women and younger patients, reports a study in the March issue of the Journal of Neuroscience Nursing, official journal of the American Association of Neuroscience Nurses.
High drug prices as well as the excessive use of imaging and surgical procedures, and excessive administrative burdens contribute the majority to America’s health care overspending compared to Europe, argues policy expert Ezekiel J. Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medicine at the University of Pennsylvania, in an editorial in this week’s JAMA.
Wolters Kluwer Health announced today that vSim® for Nursing | Mental Health and Grant’s Anatomy Lab earned Honorable Mention for eproducts in the 2018 PROSE Awards. Presented by the Association of American Publishers’ Professional and Scholarly Publishing (PSP) Division, the 42nd annual PROSE Awards recognize the best in professional and scholarly publishing.
Largest study to date addressing the prevalence of metabolic abnormalities in testicular cancer survivors who received prior chemotherapy publishes findings in the latest issue of JNCCN
Wolters Kluwer Health announced today the launch of IJS Global Health, an open access journal published in partnership with the IJS Publishing Group. The peer-reviewed, international journal will publish research in the broad field of global health and surgery.
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