Biomedical engineers have devised seizure detection software to significantly cut the number of unneeded electrical pulses an epilepsy patient receives from brain implants.
Perhaps no other biochemist in the world has his own baseball card, but Elih Velázquez-Delgado, who gave up pro ball for science, does. The doctoral student is about to publish his first academic paper on caspase-6, an enzyme that’s causally involved in Alzheimer’s and Huntington’s diseases.
Patients with unruptured brain aneurysms have significant reductions in several areas of quality of life—especially physical functioning, reports a study in the April issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Hard facts about hard hits: What athletes and parents need to know about concussions.
The first atlas of the surface of the human brain based upon genetic information has been produced by a national team of scientists, led by researchers at the University of California, San Diego School of Medicine and the VA San Diego Healthcare System. The work is published in the March 30 issue of the journal Science.
If a paramedic suspects a patient is having a stroke, the paramedic is probably right, a Loyola University Medical Center study has found. Paramedics were able to identify stroke patients with a 99.3 percent specificity.
Intravenous immune globulin (IVIg) is an effective treatment for certain disorders of the nerve and muscles, including Guillain-Barré syndrome (GBS) and a form of neuropathy called chronic inflammatory demyelinating polyneuropathy (CIDP), according to a guideline issued by the American Academy of Neurology. The guideline is published in the March 27, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences.
Protein precursors destined for the spiny extensions of neurons travel single file, according to a study by Sanjay Tyagi, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey (UMDNJ). The study recently was published in Proceedings of the National Academy of Sciences.
American Association of Neurological Surgeons focuses on concussion awareness and prevention as central theme of National Neurosurgery Awareness Week.
A new study suggests that older people may have an increased risk of problems with memory and thinking abilities after being in the hospital, according to research published in the March 21, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of dementia.
UNC researchers manipulate brain wiring to identify inner workings of reward enjoyment.
Alzheimer’s disease and other forms of dementia may spread within nerve networks in the brain by moving directly between connected neurons, instead of in other ways proposed by scientists, such as by propagating in all directions, according to researchers who report the finding in the March 22 edition of the journal Neuron.
Investigators at Nationwide Children’s Hospital, working with the DNA Sequencing Core Facility at the University of Utah, have developed an approach to newborn screening (NBS) for the life-threatening genetic disorder, Duchenne muscular dystrophy (DMD) and potentially other muscular dystrophies. As a model for NBS, the approach published online in January in the Annals of Neurology provides evidence that this approach could be implemented if approved by regulatory bodies at a state level or alternatively through the Secretary’s Advisory Committee on Heritable Disorders in Newborns and Children.
The 10th biennial interdisciplinary conference Toward a Science of Consciousness.
Loyola University Medical Center is one of the major enrollers in a landmark clinical trial that found that plugging a hole in the heart works no better than drugs in preventing strokes. The study is published in the New England Journal of Medicine.
Now a group of scientists at the University of California, San Francisco (UCSF) has discovered that a tiny molecule in the fly’s brain called neuropeptide F governs this behavior—as the levels of the molecule change in their brains, the flies’ behavior changes as well.
Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).
A study published this week in the Journal of Neuroscience shows that the compound epothilone D (EpoD) is effective in preventing further neurological damage and improving cognitive performance in a mouse model of Alzheimer's disease (AD). The results establish how the drug might be used in early-stage AD patients.
Huntington's disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a slow death sentence.
A new implantable sensor device provides a less-invasive alternative for monitoring pressure within the skull (intracranial pressure, or ICP), suggests a pilot study in Operative Neurosurgery, a quarterly supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons. Neurosurgery is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
When it comes to intergroup conflict, the group with less power benefits more from sharing its perspective according to a new study by MIT neuroscientists.
People with mild vascular disease that causes damage to the retina in the eye are more likely to have problems with thinking and memory skills because they may also have vascular disease in the brain, according to a study published in the March 14, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Nationwide ambulance use by patients suffering from a stroke has not changed since the mid-1990s, even though effective stroke treatments are now available. In a study published in this week's Journal of the American Medical Association (JAMA), researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center found that the number of stroke victims transported via ambulance has remained relatively static over the years, highlighting the need for more education about stroke symptoms and the importance of early intervention.
Shyness may be the result of deficits in two areas of the brain, new research from Vanderbilt University finds.
When you think of Botox injections, you probably think of getting rid of unwanted wrinkles around the eyes or forehead, but recently the FDA approved using the injections to help patients with neurological conditions who suffer from incontinence, or an overactive bladder.
In light of Brain Awareness Week (March 12-18), CIHR-funded researchers are available to discuss the impact of traumatic brain injury on people’s health.
Despite a century of research, memory encoding in the brain has remained mysterious. Neuronal synaptic connection strengths are involved, but synaptic components are short-lived while memories last lifetimes. This suggests synaptic information is encoded and hard-wired at a deeper, finer-grained molecular scale.
New research with monkeys sheds light on how the drug methylphenidate may affect learning and memory in children with attention deficit hyperactivity disorder.
Research suggests that a class of drugs for rheumatoid arthritis seeking approval this year could be effective against other autoimmune diseases.
Women who have multiple pregnancies may have a lower risk of developing multiple sclerosis (MS), according to research published in the March 7, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer’s disease (AD) in an animal model representative of most AD patients.
Chronic stress has a more powerful effect on the brain during adolescence than in adulthood and now there’s proof at the molecular level, according to findings published in Neuron by University at Buffalo researchers.
A case study review of an individual who received a mild brain injury from a ground-level fall while taking the anticoagulant dabigatran etexilate, and the subsequent death that resulted from "uncontrollable" bleeding.
The majority of people suffering with drug-resistant epilepsy see surgery as a last resort. But UCLA researchers show that early surgical intervention followed by antiepileptic drugs stop seizures, improve quality of life, and help avoid decades of disability.
Patients with epilepsy who underwent brain surgery soon after failing to respond to drug treatment, but who also continued to receive drug therapy, had a lower risk of seizures during the 2nd year of follow-up compared to patients who received drug treatment alone, according to a study in the March 7 issue of JAMA.
Aggressive treatment for severe traumatic brain injuries costs more than routine care, yet yields significantly better outcomes, improved quality of life, and lower long term care costs, according to a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania.
Children with mild traumatic brain injuries appear more likely to have persistent postconcussion symptoms, including cognitive complaints such as inattention and forgetfulness, which can affect quality of life, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
A new marker of Alzheimer’s disease can predict how rapidly a patient’s memory and other mental abilities will decline after the disorder is diagnosed, researchers at Washington University School of Medicine in St. Louis have found.
U-M researchers found that most patients underwent both MRIs and CTs; neuroimaging biggest source of escalating stroke care costs.
Researchers have identified a gene that causes adult-onset primary cervical dystonia, an often-painful condition in which patients’ necks twist involuntarily. The discovery by a team from the Jacksonville, Fla., campus of Mayo Clinic and the University of Tennessee Health Sciences Center sheds light on a movement disorder that physicians previously could seldom explain. Their research appears in the Annals of Neurology.
To determine whether a noninvasive surgery could effectively treat patients with a certain type of epilepsy – mesial temporal lobe epilepsy – University of Virginia School of Medicine neurologist Mark S. Quigg, MD, is helping lead an international clinical trial examining the effectiveness of Gamma Knife radiosurgery. The Gamma Knife delivers focused beams of radiation guided by MRI to the brain lesion in hopes of damaging the lesion and preventing it from causing epileptic seizures.
Studying tiny bits of genetic material that control protein formation in the brain, Johns Hopkins scientists say they have new clues to how memories are made and how drugs might someday be used to stop disruptions in the process that lead to mental illness and brain wasting diseases.
Researchers at UCLA have used specific molecular “tweezers” they developed to break-up aggregates of toxic proteins that are thought to cause Parkinson’s disease. For the first time, they stopped progression of the disease in a living animal model.
A study recently published by the University of Kentucky's Scott Livingston shows that physiological problems stemming from a concussion may continue to present in the patient even after standard symptoms subside.
Scientists at the Toronto Western Research Institute (TWRI), Krembil Neuroscience Center, have developed a drug that protects the brain against the damaging effects of a stroke in a lab setting.
A new study reveals for the first time that activating the brain’s visual cortex with a small amount of electrical stimulation actually improves our sense of smell.
We make our eye movements earlier or later in order to coordinate with movements of our arms, New York University neuroscientists have found. Their study points to a mechanism in the brain that allows for this coordination and may have implications for rehabilitation and prosthetics.
Adolescents are more sensitive to the effects of a sport-related concussion than adults or children.
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