Adding an “active choice” nudge to the electronic health record increased statin prescribing for patients with heart disease, but not for those “at-risk”
Researchers at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory are making progress on several fronts in the battle against COVID-19, the global pandemic sparked by the emergence of a novel coronavirus late last year. This work is part of a worldwide effort to understand the virus and the factors that affect its spread with the aim of devising treatments and other mitigation strategies.
Two-thirds of older adults rely on at least two prescription drugs, and more than half take two or more non-prescription drugs or supplements. But a new poll shows that most haven’t connected with a pharmacist to check for potential clashes among their prescription drugs, non-prescription drugs, and supplements, or the potential to save money by switching to lower-cost options.
Only about one in every 170 children take them. But “orphan drugs” accounted for 1 in every 15 private insurance dollars spent on children’s health care in the United States in 2018, according to a new study. That’s up 65% from just five years before.
J. Silvio Gutkind, PhD, has been named chair of the Department of Pharmacology at UC San Diego School of Medicine.
Columbia Engineering researchers report that Sofosbuvir-terminated RNA is more resistant to the proofreader of SARS-CoV-2, the virus that causes COVID-19, than Remdesivir-terminated RNA. The results of the new study, published today by the Nature Research journal Scientific Reports, support the use of the FDA-approved hepatitis C drug EPCLUSA—Sofosbuvir/Velpatasvir—in combination with other drugs in COVID-19 clinical trials.
Michigan Medicine participated in a large clinical trial which found that, in many cases, appendicitis can be safely and effectively treated with antibiotics instead of surgery.
A study exploring a new combination of therapeutic agents has recently been published in the International Journal of Molecular Sciences, describing dl922-947, an oncolytic adenovirus, and AZD1775, an inhibitor of the DNA damage checkpoint kinase WEE1, and their possible efficacy to treat MPM.
Researchers have used “omics” data containing genetic profiles of drugs to identify the hormone oxytocin as a possible treatment for COVID-19, the disease caused by the novel coronavirus (SARS-CoV-2).
Every year more than 250,000 people undergo surgery for appendicitis, making it one of the 20 most common surgeries performed in the United States. In the largest randomized U.S. study of appendicitis published today in the New England Journal of Medicine, researchers from Henry Ford Health System and 24 other sites around the U.S. report that seven in 10 patients who received antibiotics avoided surgery and that patients who took antibiotics for symptom relief fared no worse in the short term than those who underwent surgery.
A study to determine the effectiveness of the drug IP-00 in producing immune responses as a booster for the eventual vaccine for COVID-19 is being conducted by researchers in the Biophotonics & ImmunoEngineering Laboratory, led by Professor Wei R. Chen in the Stephenson School of Biomedical Engineering at the University of Oklahoma. The OU researchers are collaborating with Immunophotonics, Inc., St. Louis, Missouri, on the study.
Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to results from the national Comparing Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial published today in the New England Journal of Medicine.
The year 2020 can be summarized simply by one word - COVID-19 - as it was the culprit that froze the entire world. For more than 8 months so far, movement between nations has been paralyzed all because there are no means to prevent or treat the virus and the diagnosis takes long.
SEATTLE — Oct. 5, 2020 — Fred Hutchinson Cancer Research Center announced the opening of the COVID-19 Clinical Research Center, or CCRC. Funded by philanthropic donations and public/private partnerships, the CCRC is one of the first stand-alone facilities in the nation designed to test novel interventions to treat and prevent COVID-19.
Not only might cannabis users require more anesthesia during surgery than non-users, they may have increased pain afterwards and use higher doses of opioids while in the hospital, suggests first-of-its kind research being presented at the ANESTHESIOLOGY® 2020 annual meeting.
Eppendorf, a leading life science company, announces that its Americas Market Region Commercial headquarters officially moved from Hauppauge, NY to Framingham, MA.
The American College of Surgeons Clinical Congress 2020 (Oct. 3-7) is a virtual-only event. Here’s the listing of next week’s activities for media attendees.
Seven of 10 adults with appendicitis can safely avoid surgical removal of their appendix (appendectomy) for at least several months by receiving a course of antibiotics.
Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of Drugs and Appendectomy (CODA) trial.
A multinational clinical trial of for the treatment of Niemann-Pick disease Type C (NPC) demonstrated a statistically significant and clinically meaningful improvement in symptoms, functioning, and quality of life in both primary and topline secondary endpoints for both pediatric and adult patients with NPC.
Artificial intelligence (AI) used in machine learning models can predict which patients are at highest risk for severe pain after surgery, and help determine who would most benefit from personalized pain management plans that use non-opioid alternatives, suggests new research being presented at the ANESTHESIOLOGY® 2020 annual meeting.
New research presented at the virtual American College of Surgeons Clinical Congress 2020 reports that opioid guidelines may be missing a small group of patients that need a greater level of pain control.
Almost 20 years into the opioid epidemic, there finally is evidence of significant and continual decreases in the abuse of these risky pain medications, according to an analysis of national data being presented at the ANESTHESIOLOGY® 2020 annual meeting.
Drugs to lower blood pressure of the type ACE inhibitors or angiotensin II receptor blockers reduce the mortality rate of influenza and pneumonia.
University at Buffalo researchers have received a grant from the Community Pharmacy Foundation to help add community health workers to pharmacies to better connect patients to critical services and lower health care costs.
The immunotherapy drug atezolizumab improves survival over standard chemotherapy for many patients with newly diagnosed non-small cell lung cancer, according to a new study led by Yale Cancer Center researchers.
Rutgers researchers have reported an increased mortality risk in adults with depression who initiated augmentation with newer antipsychotic medications compared to a control group that initiated augmentation with a second antidepressant.
In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as “lazy eye.”
Clinical trial shows health care workers in contact with COVID-19 patients who took hydroxychloroquine each day did not reduce their rate of infection
Women and racial minorities are seriously underrepresented in trials of medicines for alcohol use disorder (AUD) despite evidence that these treatments affect demographic groups differently. This is according to a review in Alcoholism: Clinical & Experimental Research, which may be the first to evaluate sex and racial representation in studies relating to the three pharmacological treatments approved by the Food and Drug Administration (FDA) for AUD. Previous research indicates that sex and race/ethnicity likely influence the prevalence of AUD, its risk of health consequences, and the effectiveness of treatments.
Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior. Now, a new study by Johns Hopkins Medicine researchers affirms that meth use increases not only sexual desire but also, specifically and measurably, the risk of casual sex without a condom for those who have an increase in sexual desire.
October is National Dental Hygiene Month, and ADHA and Colgate have partnered to celebrate dental hygienists.
Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturised antibodies, opening the way for a potential new class of treatments for diseases.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Parkinson’s disease is most commonly treated with levodopa, but the benefits wear off as the disease progresses and high doses can result in dyskinesia, which are involuntary and uncontrollable movements. To better understand the underlying reasons behind these effects, researchers created a model of the interactions between levodopa, dopamine, and the basal ganglia, an area of the brain that plays a crucial role in Parkinson’s disease. They discuss their findings in the journal Chaos.
Approvals of prescription opioids by the U.S. Food and Drug Administration over more than two decades have been based on evaluations in narrowly defined patient groups for which certain safety-related outcomes have been rarely systematically assessed, according to a new analysis from researchers at the Johns Hopkins Bloomberg School of Public Health.
UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today in Nature Cell Biology, could lead to better therapies for patients with lung disease, including acute respiratory distress syndrome (ARDS) due to COVID-19.
A combination antibody treatment for preventing COVID-19 illness in individuals who have had sustained exposure to someone with the virus is being studied by researchers at The University of Texas Health Science Center at Houston (UTHealth). The clinical trial is enrolling patients at Harris Health System’s Lyndon B. Johnson Hospital.
The NIH has awarded NYU College of Dentistry researchers Nigel Bunnett, PhD, and Brian Schmidt, DDS, MD, PhD, a $3.9 million grant to study targeting endosomal receptors for the treatment of chronic pain. The five-year grant will support Bunnett and Schmidt’s collaborative research, which aims to ultimately yield improved pain management without the need for opioids.
Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.
Según una investigación de Mayo Clinic en la que participaron 667 pacientes que recibieron trasplante pulmonar entre el 2005 y el 2018, los medicamentos antimicóticos preventivos reducen a la mitad el riesgo de mortalidad en el primer año luego del trasplante de pulmón.
DALLAS – Sept. 24, 2020 – Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes – parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published online today in Science, could change the course of this disease that kills up to 250,000 people a year.
The University of New Hampshire will receive $1.8 million from the National Institutes of Health (NIH) that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.
Researchers have sequenced the genome of Alexander Fleming's penicillin mould for the first time and compared it to later versions.
The University of Texas MD Anderson Cancer Center and Taiho Pharmaceutical Co., Ltd., today announced a three-year strategic collaboration to accelerate the development of treatments for significant unmet medical needs in oncology, including patients with brain metastases and those with cancers refractory to available therapies.
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