NorthShore University HealthSystem, Evanston, IL, presented a talk titled, “Clinical utility of the Streck ARM-D Kits to detect antimicrobial resistance genes from extracts of axillary, throat and rectal swabs” at ASM Microbe 2018.
The opioid crisis has made physicians increasingly wary about prescribing the potentially addictive drugs to their patients in pain. But there is a silver lining – experts in pain medicine, such as physician anesthesiologists, can create individualized pain management plans that include alternatives to opioids that are safer and often work better.
Oncologists from Children’s Hospital of Philadelphia today celebrated a watershed moment in medicine: approval by the European Commission of Kymriah (tisagenlecleucel, formerly CTL019) --the first-ever FDA-approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers, pioneered together with Novartis and the Perelman School of Medicine at the University of Pennsylvania.
Adding another inhibitor to therapies that cut off a tumor’s access to blood vessels could be the key to helping those therapies overcome resistance in glioblastoma, a deadly form of brain cancer.
A study led by Columbia University cardiologist Mathew Maurer showed that tafamidis reduces deaths from a type of heart failure called transthyretin amyloid cardiomyopathy. The drug could be one of the first effective treatments for the disease.
•On a national level, implementation of antimicrobial stewardships in outpatient dialysis facilities would result in 2182 fewer infections caused by multidrug-resistant organisms and Clostridium difficile (a 4.8% reduction) per year. • It would also lead to 629 fewer infection-related deaths (a 4.6% reduction) and a cost savings of $99,804,603 (a 4.7% reduction) per year.
In this issue, find research on school shootings and long gun age restrictions, Russian anti-vaccine trolls, smoke-free colleges and more.
Using the BioSANS instrument at DOE’s ORNL, a team of researchers from the University of Pennsylvania’s Perelman School of Medicine explores future HIV treatments. Specifically, the researchers hope to better understand how HIV evolves to combat ALLINIs, a new class of HIV-fighting drug. With the information they’ve gathered at ORNL, the researchers hope to pave the way for more effective HIV treatments in the future.
Johns Hopkins University School of Medicine leaders plan to invest $100 million over the next five years to hire new faculty and support programs aimed at unraveling the mysteries of biology. Such “basic” science discoveries underpin virtually every major medical breakthrough, say the leaders, and they have appointed structural biologist James Berger, Ph.D., to direct the Johns Hopkins institute dedicated to this effort.
Although black and Hispanic veterans with chronic kidney disease (CKD) are more likely than white patients to see a kidney specialist—a nephrologist—they are more likely to suffer disease progression from early stage to advanced kidney disease, reports a study published this month in the Journal of the American Society of Nephrology from researchers at the Perelman School of Medicine at the University of Pennsylvania.
The College of American Pathologists (CAP) published the 2018 edition of its accreditation program checklists on August 22, 2018, providing medical laboratories a blueprint for maintaining compliance with the Centers for Medicare and Medicaid Services (CMS) regulations.
Christopher Kane, MD, has been appointed dean of clinical affairs for UC San Diego School of Medicine and CEO of UC San Diego Health Physicians, effective July 15. In these dual roles, Kane will collaborate with UC San Diego leadership to ensure that UC San Diego Health Physicians achieve the highest standards of service, access, quality, safety, and patient satisfaction and are integrated to support the unique and growing needs of an expanding academic health system and its growing regional network of providers.
Ludwig Cancer Research is pleased to welcome Nancy E. Davidson to the Ludwig Institute Board of Directors. Nancy Davidson, a physician-scientist with extensive expertise in breast cancer research, is a leader in the cancer research community.
Launches Integrated marketing campaign in Support of US Open Partnership
Value in Health Regional Issues, a MEDLINE®-indexed journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of an article highlighting the positive results of a pilot project launched by the Chinese central government. The project intended to negotiate approval on the China National Formulary for innovative medicines that had been previously unapproved because of their relatively high cost.
Alumni of the UVA Darden School of Business span the globe, with a thriving network of 16,000-plus spread across 90 countries. They hold leadership positions at top companies in New York and Beijing, San Francisco and Delhi. However, the pull of Darden’s geographic home in Charlottesville remains impossible to resist for many.
A comprehensive analysis of eight clinical trials and four cohort studies on cervical cancer screening by researchers from UC Davis and Kaiser Permanente Northwest has found that while Pap smears are still highly effective for detecting pre-cancerous cells and cancer, testing for the virus that causes these cancers also is an excellent screening tool.
At a time when drug overdoses are becoming more prevalent and lethal, a new report provides a snapshot of regional illicit drug use and, for the first time, highlights the complexity of detecting and treating patients at hospital emergency departments for a severe drug-related event.
Most animals have a keen sense of smell, which assists them in everyday tasks. Now, a new study led by researchers at NYU School of Medicine sheds light on exactly how animals follow smells.
A multidisciplinary research team led by Beth Israel Deaconess Medical Center has determined that vitamin B3 has the potential to prevent acute kidney injury. Published in Nature Medicine, the findings bring clinicians one step closer to an accessible and safe therapy for patients who may be at risk.
A patient blood management program designed to limit the amount of transfused blood orthopedic patients undergoing common surgeries such as hip and knee replacement receive was associated with fewer transfusions, reduced blood use and improved outcomes, reports a study published in the Online First edition of Anesthesiology.
A drug policy researcher is proposing changes to the Multi-Criteria Drug Harm Scale, which informs European drug policies. The changes focus on addressing use and abuse separately, collecting input from a broader range of stakeholders, and targeting substance-specific experts for drug review panels.
A unique pain program is helping complex surgical patients wean off opioids safely and effectively, while offering alternative ways to cope with their pain and improve how they function.
About 50,000 people in the U.S. are diagnosed annually with head, neck, nasal and oral cancers. Most are treated with radiation, and of those, 70-80 percent develop a painful and debilitating side effect called severe oral mucositis (SOM).
In 2008, a contaminant eluded the quality safeguards in the pharmaceutical industry and infiltrated a large portion of the supply of the popular blood thinner heparin, sickening hundreds and killing about 100 in the U.S.
A new opioid misuse prevention program called ONE Rx was announced by pharmacy and health care partners in North Dakota. This continuing education program for pharmacists at community pharmacies moves opioid misuse and overdose prevention to the initial patient encounter, increasing awareness when patients first fill an opioid prescription.
When enrolled in a cancer clinical trial, the differences in survival rates between rural and urban patients are significantly reduced, SWOG study results show.
Researchers have found that cholesterol-lowering statins may improve the conditions of people with a rare lung disease called autoimmune pulmonary alveolar proteinosis. The research also suggested that two new tests could help diagnose the condition.
Researchers from the George Washington University published an article in Trends in Parasitology outlining their lessons learned while creating vaccine candidates for hookworm and schistosomiasis.
Island Fertility has joined Stony Brook Community Medical, expanding to 23 the number of Stony Brook Medicine’s network of community practices and physicians.
A multidisciplinary research team led by Case Western Reserve University School of Medicine has received a three-year, $936,000 grant to use collaborative computational modeling approaches to promote better community health through more equitable food systems.
“High risk, high reward” is the kind of discovery Dr. Garry Grubbs seeks with a new experiment designed to rapidly identify the atomic structure of chiral molecules widely used in pharmaceutical drugs. The finding could significantly reduce the time and costs involved in pharmaceutical development and manufacturing.
Researchers discovered a gene mutation underlying hydrops fetalis – a fatal condition to fetuses. The proteins at the center of this finding are implicated in a number of diseases, opening avenues of potential drug discovery related to migraines, diabetes, osteoporosis, and other conditions.
Neuroendocrine cancer is rare and hard to diagnose – and it can be difficult to treat and to survive. To help make more accurate diagnoses more quickly, the UNM Department of Radiology recently started using a new, injectable imaging agent to pinpoint neuroendocrine tumors. And in October, UNM Cancer Center will begin offering a new treatment that uses part of that imaging agent to fight the tumors.
Researchers at Hospital for Special Surgery (HSS) have discovered that a type of immune cell known as Langerhans appears to play an important role in photosensitivity, an immune system reaction to sunlight that can trigger severe skin rashes.
In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.
By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion.
The blood-brain barrier is a specialized network of vascular and brain cells that acts as the brain’s security system, helping to safeguard the brain and regulate the flow of substances into and out of it.
The National Institutes of Health (NIH) have awarded $6.5 million to a consortium that includes the Icahn Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai
The diabetes epidemic in Guatemala is worse than previously thought: more than 25 percent of its indigenous people, who make up 60 percent of the population, suffer from type 2 diabetes or pre-diabetes, suggests a new study published in PLOS One from researchers at the Penn Center for Global Health.
Switching anti-psychotic medications does not improve clinical outcomes in patients with first-episode schizophrenia who haven’t responded to treatment, Mount Sinai researchers have shown for the first time.
Treatment guidelines say patients who undergo minimally invasive aortic heart valve replacements should receive two antiplatelet drugs to reduce the risk of dangerous blood clots. A Loyola Medicine study has found that a single antiplatelet drug may work just as well, with lower risks of life-threatening bleeding and other complications.
OncoThira will develop and market compounds discovered by NDSU pharmaceutical sciences researcher Steven Qian that take advantage of high COX-2 expression in cancer to down regulate cancer promoting prostaglandins and elevate production of the recently characterized anti-cancer compound 8-HOA
University of Illinois at Chicago researchers have received approximately $2 million in funding from the National Institutes of Health to develop a better way to regenerate bone or tissues that have been lost to disease or injury.
Argonne chemist Stephen Klippenstein has received a gold medal from The Combustion Institute, one of the highest honors given in the field of combustion chemistry.
The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease (SCD) in individuals who do not have asthma.
Hackensack Meridian Health Bayshore Medical Center in Holmdel, has again been awarded a three-year term of accreditation in ultrasound as a result of an extensive review by the American College of Radiology (ACR). Ultrasound imaging, also known as sonography, uses high-frequency sound waves to produce images of internal body parts to help providers diagnose illness, injury or other medical problems.
Joseph W. Polli, Ph.D., FAAPS, GlaxoSmithKline has been elected to serve as president-elect of the American Association of Pharmaceutical Scientists (AAPS), a professional member-based organization of approximately 9,000 located in Arlington, VA.
A multidisciplinary team of researchers from the National University of Singapore (NUS) has developed an artificial intelligence (AI) technology platform that could potentially change the way drug combinations are being designed, hence enabling doctors to determine the most effective drug combination for a patient quickly
ASRA's fourth exam candidates have been certified.
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