Government legislation to flag and moderate dangerous content on social media can be effective in reducing harm, even on fast-paced platforms such as X (formerly Twitter) new research shows.
Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes. These enzymes are growing increasingly common, appearing worldwide in clinical samples in a range of drug-resistant bacteria.
Life’s random rhythms surround us–from the hypnotic, synchronized blinking of fireflies…to the back-and-forth motion of a child’s swing… to slight variations in the otherwise steady lub-dub of the human heart. Now, an international team says it has developed a novel, universal framework for comparing and contrasting those oscillations--regardless of their different underlying mechanisms—which could become a critical step toward someday fully understanding them.
Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular ‘ZIP code’ in the lungs, with implications for improved diagnostics and treatments, including patients with severe human respiratory diseases such as emphysema, COVID-19, COPD and lung cancer.
Soil is the most species-rich habitat on earth. This is the conclusion of an overview study by a Swiss research team. According to the study, two thirds of all known species live in the soil.
Geoscientists have long thought that water – along with shallow magma stored in Earth’s crust – drives volcanoes to erupt. Now, thanks to newly developed research tools at Cornell, scientists have learned that gaseous carbon dioxide can trigger explosive eruptions.
Researchers from the Hessian State Museum Darmstadt and the Senckenberg Biodiversity and Climate Research Center Frankfurt have uncovered the factors that determine the enormous diversity of herbivorous insects.
UCLA Health researchers have published the largest-ever study of families with at least two children with autism, uncovering new risk genes and providing new insights into how genetics influence whether someone develops autism spectrum disorder.
A new study by scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University suggests that a micronutrient in human breast milk provides significant benefit to the developing brains of newborns, a finding that further illuminates the link between nutrition and brain health and could help improve infant formulas used in circumstances when breastfeeding isn’t possible.
Lab-on-a-chip technologies can ensure a more successful transfusion workflow by enabling objective assessment of stored RBC units using quality metrics identified by -omics and machine learning.
Immune-checkpoint inhibitors have become the standard of care for patients with advanced melanoma to improve survival, but only some patients respond to this immunotherapy and have long-term benefits. The lack of a long-lasting response, researchers say, is related to failure of antitumor immunologic memory. Treatment options for advanced melanoma are limited for patients who do not respond to this type of therapy.
New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes’ on/off switches.
A new study published in PNAS evaluates the effects of Saharan dust clouds on atmospheric methane. An international research team found that when mineral dust that mixes with sea-spray to form Mineral-Dust-Sea Spray Aerosol (MDSA), this MDSA is activated by sunlight to produce an abundance of chlorine atoms ultimately mitigating methane totals.
Researchers have created a unique microscopic toolkit of ‘green’ tuneable electrical components, paving the way for a new generation of bioelectronic devices and sensors.
A new study by researchers at Case Western Reserve University revealed that the progression of Alzheimer's disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion.
A team of researchers from the University of Maryland School of Maryland’s Institute of Human Virology published new findings that emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development.
Researchers at the University of Illinois Urbana-Champaign and collaborators at Merck & Co. developed a rapid and efficient method of making large quantities of metabolites directly from a drug or drug precursors via carbon-hydrogen oxidation catalysis.
A team led by Dr. Miquel Coll at the Institute for Research in Biomedicine (IRB Barcelona) and the Institute of Molecular Biology of Barcelona (IBMB-CSIC), in collaboration with researchers led by Dr. Eric Krukonis at the University of Detroit Mercy in the USA, has revealed the atomic structure of the ToxR protein bound to the DNA of two promoters of the genes that cause the virulence of this bacterium.
Using a combination of high-powered X-rays, phase-retrieval algorithms and machine learning, Cornell researchers revealed the intricate nanotextures in thin-film materials, offering scientists a new, streamlined approach to analyzing potential candidates for quantum computing and microelectronics, among other applications.
Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines have identified an enzyme that plays a critical role in the late stages of HIV replication.
Johns Hopkins Medicine scientists say they have developed a nanoparticle — an extremely tiny biodegradable container — that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.
Orangutans can make two separate sounds simultaneously, much like songbirds or human beatboxers, according to a study led by the University of Warwick.
Researchers from the University of Illinois Chicago used the Theta supercomputer at the Argonne Leadership Computing Facility to run simulations on and determine the molecular mechanisms behind the ways that new HIV antivirals could work.
People rely on sight to identify weeds but ants grow fungus underground in the dark and must have other ways to sense undesirable garden denizens. A team led by Jonathan Klassen, Ph.D., at the University of Connecticut and Marcy Balunas, Ph.D., at the University of Michigan has found that the ants sniff out diseased fungus by detecting chemicals called peptaibols.
A new study from researchers at the University of Wisconsin–Madison offers a first-of-its-kind visual of a non-mammal species' adaptive immune system in action. The advance holds potential implications for a range of scientific aims, from improving wildlife vaccines to better understanding fundamental disease processes and possibly the evolution of adaptive immunity itself.
Researchers from Children’s Hospital of Philadelphia (CHOP) have engineered stable, universal MHC-I molecules that can be produced rapidly at scale, allowing researchers not only to develop vaccines and immunotherapies more quickly but also to identify molecules that can work broadly across the population. The findings were published today in the Proceedings of the National Academy of Sciences.
The persistent gender gap in voting for Democrats versus Republicans is, in part, because a higher proportion of women than men voters are Black and because Black voters have historically voted overwhelmingly Democratic, according to a new study by a team of sociologists.
Genetic variation is the ultimate fuel for evolution, says Utah State University evolutionary geneticist Zachariah Gompert. But, over centuries, that fuel reservoir gets depleted in the course of natural selection and random genetic drift.
Prostate cancer is the most-commonly diagnosed malignancy and the second leading cause of cancer death among men in the United States. In its ever-indelicate world, the stubborn disease can continue to grow even when the amount of testosterone in the body is reduced to very low levels, thus earning the clumsy name: castrate-resistant prostate cancer (CRPC).
A new acoustic microfluidic method offers opportunities to conduct experiments with swimming cells and microorganisms. With it, ultrasonic waves like those used for imaging are able to hold a cell’s body in place without affecting the way it swims.
In the quarter century between 1996 and 2020, wildfires in California consumed five times more area than they did from 1971 to 1995. Researchers at the University of California and other international institutions have concluded that nearly all of the increase in scorched terrain can be blamed on human-caused climate change.
A new study by a Lawrence Livermore National Laboratory (LLNL) scientist and collaborators shows that nearly all the recent increase in summer wildfire burned area in California is attributable to human-caused (anthropogenic) climate change. Anthropogenic simulations yielded burn areas an average of 172% higher than natural variation simulations.
Tightly curled scalp hair protected early humans from the sun’s radiative heat, allowing their brains to grow to sizes comparable to those of modern humans. Loughborough University researchers in the UK worked with Penn State University to study heat transfer through human hair wigs and the environment to examine how diverse hair textures affect heat gain from solar radiation.
Our familiar, warm, yellow sun is a relative rarity in the Milky Way. By far the most common stars are considerably smaller and cooler, sporting just half the mass of our sun at most. Billions of planets orbit these common dwarf stars in our galaxy.
Human influences have the potential to reduce the effectivity of communication in bees adding further stress to struggling colonies, according to new analysis.
New research by Gillingham, published in Proceedings of the National Academy of Sciences, finds that recent adoption of EVs is driven overwhelmingly by technological advances, while general consumer preferences for EVs has changed little.
Study suggests person-to-person transmission may not be the dominant mode of infection for an aggressive lung pathogen.
Findings shed light on the behavior and mutation tendencies of a little-known microbe.
The results should ease fears that the lung bacterium poses a grave threat for spread between individuals with compromised lung function who are waiting for lung transplants.
Age-related memory loss is caused, in part, by lack of flavanols—nutrients found in certain fruits and vegetables—according to a large study in older adults.
A new study used global storm-resolving simulations and machine learning to create an algorithm that can deal with two different scales of cloud organization. This new approach addresses the missing piece of information in traditional climate model parameterizations and provides a way to predict precipitation intensity and variability more precisely.
Powerful magnetic pulses applied to the scalp to stimulate the brain can bring fast relief to many severely depressed patients for whom standard treatments have failed. Yet it’s been a mystery exactly how transcranial magnetic stimulation, as the treatment is known, changes the brain to dissipate depression. Now, research led by Stanford Medicine scientists has found that the treatment works by reversing the direction of abnormal brain signals.
A new study led by climate researchers at Columbia Engineering and the University of Exeter demonstrates that the treaty’s impact reaches all the way into the Arctic: its implementation is delaying the occurrence of the first ice-free Arctic by as much as 15 years.
For more than 10 years, Guoliang Huang, the Huber and Helen Croft Chair in Engineering at the University of Missouri, has been investigating the unconventional properties of “metamaterials” — an artificial material that exhibits properties not commonly found in nature as defined by Newton’s laws of motion — in his long-term pursuit of designing an ideal metamaterial.
The theory of relativity works well when you want to explain cosmic-scale phenomena - such as the gravitational waves created when black holes collide. Quantum theory works well when describing particle-scale phenomena - such as the behavior of individual electrons in an atom.