Monroe Carell Jr. Children’s Hospital at Vanderbilt is seeing a spike in respiratory illnesses, especially RSV (respiratory syncytial virus) and parainfluenza, which cause croup and bronchiolitis in young children and flu-like symptoms in older children and adults
All Virtual Conference To Highlight PF Research And Quality Of Life Nov. 8-13
In a new article published in the Journal for ImmunoTherapy of Cancer, Moffitt Cancer Center researchers show that PET/CT images can be used to measure levels of the PD-L1 biomarker of non-small cell lung cancer (NSCLC) patients in a non-invasive manner and, in turn, predict a patient’s response to therapy.
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue. Inflammation was completely treated in mice given the nanoparticles, at a drug concentration where standard delivery methods did not have any efficacy.
From studies in her lab at Stony Brook University in New York to private-sector collaborations, Hertz Fellow Jessica Seeliger is accelerating the fight against multiple deadly diseases.
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Immune cells that normally repair tissues in the body can be fooled by tumors when cancer starts forming in the lungs and instead help the tumor become invasive, according to a surprising discovery reported by Mount Sinai scientists in Nature in June.
Exposure to the rhinovirus, the most frequent cause of the common cold, can protect against infection by the virus which causes COVID-19, Yale researchers have found.
Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.
A new study finds that manipulating the stiffness of the collagen-based support structure of airway cells could lead to a new treatment for asthma. The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for June.
The Pulmonary Fibrosis Foundation (PFF) and Paradigm Medical Communications, LLC , have announced a collaborative partnership to design and implement a curriculum of continuing medical education (CME) activities in interstitial lung disease (ILD).
Researchers have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote tissue repair through treatment with microgel-coated mesenchymal stromal cells.
Scientists have published the first detailed atomic-level model of the SARS-CoV-2 "envelope" protein bound to a human protein essential for maintaining the lining of the lungs. The findings may speed the search for drugs to block the most severe effects of COVID-19.
A new Houston Methodist study shows a rapid return of seasonal respiratory viruses after COVID-19 restrictions were relaxed in Texas, demonstrating the apparent effectiveness of masking, distancing and other precautionary measures at stopping the spread of respiratory illnesses. This rise in infections to pre-pandemic levels followed updated governmental guidelines lifting mask, distancing and occupancy requirements.
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial led by Washington University School of Medicine in St. Louis. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with lung adenocarcinoma, a common type of non-small-cell lung cancer.
Two easily measurable signs of health are distinctly predictive of higher mortality among patients hospitalized with COVID-19, according to a study examining the cases of inpatients with COVID-19 at Rush University Medical Center and University of Washington Medicine hospitals.
Artificial intelligence (AI) technology developed by researchers at the University of Waterloo is capable of assessing the severity of COVID-19 cases with a promising degree of accuracy.
In patients with non-small cell Lung Cancer (NSCLC), the presence of either high chronic inflammation, or procalcitonin levels in the blood as a response to bacterial infection, both predict a poor response to treatment with immune checkpoint blockade.
Hyperpolarised xenon MRI detected lung damage which was not picked up by routine CT scans and clinical tests
A new innovation that holds promise to fight lung cancer is now in use at University Hospitals Cleveland Medical Center.
To lower hospital readmission rates for patients with chronic obstructive pulmonary disease (COPD), University at Buffalo pharmacy researcher David Jacobs has received a $962,000 award from the National Heart, Lung, and Blood Institute to develop a real-time readmission risk prediction algorithm.
Approximately two-fifths of Medicare beneficiaries with chronic obstructive pulmonary disease (COPD) have limited access to pulmonary rehabilitation services due to their distance from rehab centers, according to research presented at the ATS 2021 International Conference. More than 24 million U.S. adults suffer from COPD, a smoking related disease.
Environmental tobacco smoke exposure in utero and during early childhood—especially secondhand smoke—is associated with decreased childhood lung function, according to research presented at the ATS 2021 International Conference.
Kolb is research director at the Firestone Institute for Respiratory Health at McMaster and St. Joseph’s Healthcare Hamilton, as well as division director for respirology at the Department of Medicine. He is also the European Respiratory Journal’s chief editor.
Air quality standards recommended by the American Thoracic Society (ATS) have the potential to prevent more illness and death than standards adopted by the U.S. Environmental Protection Agency (EPA), according to research presented at the ATS 2021 International Conference.
To mark Clinical Trials Day on May 20, the Pulmonary Fibrosis Foundation (PFF) aims to herald the positive impact clinical trials have made on the pulmonary fibrosis (PF) community, the current advancements in research and the importance of patient involvement.
The American Thoracic Society has named Polly E. Parsons, MD, ATSF, and past president of the ATS, as the 2021 Edward Livingston Trudeau Medalist. The award was presented during the 2021 ATS International Conference.
Patients with idiopathic pulmonary fibrosis (IPF), a rare lung disease that causes shortness of breath and low oxygen levels because of lung scarring, have worse outcomes if they live in poor neighborhoods, according to research presented at the ATS 2021 International Conference.
By removing “race correction” from the interpretation of pulmonary function test (PFT) results, Black individuals were shown to have a significantly higher prevalence and severity of lung disease, according to research presented at the ATS 2021 International Conference.
A new study led by University of Liverpool researchers has confirmed that children with cystic fibrosis (CF) in the US have better lung function than UK children with the disease.
The use of e-cigarettes is associated with wheezing and shortness of breath in young adults and adolescents, even in those who don’t smoke cigarettes or marijuana, according to research presented at the ATS 2021 International Conference.
World-first nanotechnology developed by the University of South Australia could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, increasing its efficacy by up to 100,000-fold.
Trained to see patterns by analyzing thousands of chest X-rays, a computer program predicted with up to 80 percent accuracy which COVID-19 patients would develop life-threatening complications within four days, a new study finds.
An acute loss of smell is one of the most common symptoms of COVID-19, but for two decades it has been linked to other maladies among them Parkinson’s disease and dementia. Now, a poor sense of smell may signify a higher risk of pneumonia in older adults, says a team of Michigan State University researchers.
Published today in Nature Communications, the team from the Peter Doherty Institute for Infection and Immunity (Doherty Institute), Alfred Health and Monash University sought to understand which patients would recover quickly from influenza and which would become severely ill.
University Hospitals in Cleveland is the global pioneer in full clinical adoption of GE Healthcare’s new Critical Care Suite 2.0, the world’s first on-device artificial intelligence program helping to assess endotracheal tube placement.
呼吸气溶胶是呼吸气体的常见组成部分，也是COVID-19等呼吸道病毒传播给他人和各种表面的常见途径。在妙佑医疗国际(Mayo Clinic) 对心脏病患者进行运动负荷试验的研究人员发现，随着运动强度的增加，房间周围气溶胶的浓度也会增加。他们还发现，高效微粒空气过滤器(HEPA)可有效地过滤气溶胶，减少患者之间更换清新空气所需的时间。
مدينة روتشستر، ولاية مينيسوتا — رذاذ الأيروسول التنفسي مكون شائع للنفس، وطريقة شائعة لنشر فيروسات الجهاز التنفسي مثل فيروس كورونا المستجد (كوفيد-19) إلى الأشخاص والأسطح الأخرى. وجد الباحثون الذين أجروا اختبارات الإجهاد المتعلقة بالتمارين لمرضى القلب في مايو كلينك أن ممارسة الرياضة بمستويات متزايدة من المجهود تزيد من تركيز الأيروسول في الغرفة المحيطة. ووجدوا أيضًا أن منقيات جزيئات الهواء عالية الكفاءة (HEPA) ترشح رذاذ الأيروسول بشكل فعال وتقلل الوقت اللازم لتنقية الهواء بين المرضى.
A pioneering study by UCL scientists has discovered the presence of a harmful inflammatory protein in patients with symptomatic tuberculosis (TB).
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Aerossóis respiratórios são um componente comum da respiração e são uma forma comum de vírus respiratórios, como o COVID-19 , se espalharem para outras pessoas e superfícies. Os pesquisadores que realizam testes de esforço físico para pacientes cardíacos na Mayo Clinic descobriram que praticar exercícios em níveis crescentes de esforço aumentava a concentração de aerossol no ambiente ao redor. Eles também descobriram que um filtro de ar particulado de alta eficiência (HEPA) filtrou de forma eficaz os aerossóis e diminuiu o tempo necessário para limpar o ar entre os pacientes.
Los aerosoles respiratorios son un componente común de la respiración y constituyen una vía común de propagación de virus respiratorios como la COVID-19 a personas y superficies. Los investigadores que realizan pruebas de esfuerzo físico en pacientes con problemas cardíacos en Mayo Clinic hallaron que el ejercicio a niveles mayores de esfuerzo aumentaba la concentración de aerosoles en el entorno circundante. Además, descubrieron que el filtro recogedor de partículas de alta eficiencia (HEPA, por sus siglas en inglés) descartaba de manera eficaz los aerosoles y disminuía el tiempo necesario para purificar el aire entre los pacientes.
By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy.
Asthma attacks account for almost 50 percent of the cost of asthma care which totals $80 billion each year in the United States
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis.
After the Most Comprehensive Review to Date, a Panel of Leading Medical Experts Conclude that Ivermectin Should be Systematically and Globally Adopted for the Prevention and Treatment of COVID-19
In their lab, CRCHUM scientists Emmanuelle Brochiero and Damien Adam are studying ways of better predicting the efficacy of medications and helping injured lungs repair and regenerate.
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis.
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