People living in Appalachia are three times more likely to die from diabetes than someone living in most other parts of the United States. Now seven academic centers and community organizations have created the Appalachian Translational Research Network to tackle diabetes, obesity and other health problems using translational science - an approach that uses collaborations to help accelerate the time it takes basic research to become usable health solutions.
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) found that while black and white children with vitamin D deficiency both had higher fat levels, black children were more likely to have higher levels of fat just under their skin and white children were more likely to have higher levels of fat between their internal organs.
Researchers at the University of California, San Diego School of Medicine, the National Institutes of Health (NIH) and the Mayo Clinic have published promising results of a clinical study using an experimental anti-fibrotic and anti-inflammatory drug called pirfenidone to treat patients with diabetic nephropathy.
Researchers from Mount Sinai School of Medicine have for the first time determined that the ketogenic diet, a specialized high-fat, low carbohydrate diet, may reverse impaired kidney function in people with Type 1 and Type 2 diabetes.
The brain’s hypothalamus plays a key role in obesity and one of its major complications – type 2 diabetes. Nerve cells in the hypothalamus detect nutrients and hormones circulating in the blood and then coordinate a complex series of behavioral and physiological responses to maintain a balance between calories eaten and calories burned. Obesity and diabetes can result when this regulatory mechanism goes awry.
A new study of older diabetes patients has found that well-controlled blood sugar levels were associated with a lower risk of major complications but the very lowest blood sugar levels were associated with a small but significant increased risk of death.
John Walker, M.D., C.P.E., Chief Medical Officer, Cornerstone Health Care, is presenting Cornerstone’s successful use of Humedica MinedShareTM Ambulatory as a basis for its new Patient Care Advocate program. Joining Dr. Walker in the presentation are John Cuddeback, M.D., Ph.D. Chief Medical Informatics Officer, Anceta and A.G. Breitenstein, J.D., M.P.H., Vice President & General Manager, Provider Markets, Humedica.
Eye examinations every other year are more cost-effective than currently recommended annual eye exams for people with diabetes who are at low risk of diabetic retinopathy progression.
A new book by University of Utah School of Medicine faculty Robert E. Jones, M.D., FACP, FACE, and Kathleen B. Digre, M.D., take an in-depth look at diabetes and provide a practical approach for health care providers caring for women with the disease.
The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain, the burning or tingling pain in the hands and feet that affects millions of people with diabetes. The guideline is published in the April 11, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 11, 2011, at the American Academy of Neurology’s Annual Meeting in Honolulu.
An intensive program that taught low-income, poorly educated diabetics to better manage their disease resulted in significantly improved long-term blood sugar control, according to Johns Hopkins researchers who designed and implemented the program.
Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, also showed an association between diabetes and higher cancer mortality rates.
The proportion of poor adults age 40 and over with diabetes who had their blood sugar, eyes and feet examined at least once a year dropped from 39 percent to 23 percent between 2002 and 2007.
Middle-aged adults with diabetes are much more likely to develop age-related conditions than their counterparts who don’t have diabetes, according to a new study by the University of Michigan Health System and VA Ann Arbor Healthcare System.
Physicians at The University of Texas Health Science Center at Houston (UTHealth) have begun enrollment for a pilot study on a promising surgical approach for the management of Type 2 diabetes.
In the longest study of its kind, bariatric surgery has been shown to reduce the risk of heart attack and stroke in patients with diabetes. These results and other groundbreaking research were presented at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.
Bariatric surgery is an especially cost-effective therapy for managing Type 2 diabetes in moderately and severely obese patients. These findings and others were presented today at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.
A study by Joslin Diabetes Center researchers has found that some people who have survived diabetes for many decades show remarkably few complications—a discovery that points toward the presence of protective factors that guard against the disease's effects.
The International Diabetes Federation now recommends that surgery be considered as a treatment for obese patients with type 2 diabetes. Dr. Allison Goldfine, head of clinical research at Joslin Diabetes Center, is available for comment.
GW researchers have been awarded two grants from the McKesson Foundation as part of its Mobilizing for Health initiative, an initiative to improve the health of underserved populations with chronic diseases through the use of mobile-phone technology. The Mobilizing for Health grants, of up to $250,000 each, will support studies on diabetes care and management. GW researchers received two of the six grants awarded in a national competition.
Bariatric surgery should be considered earlier in the treatment of eligible patients to help stem the serious complications that can result from diabetes, according to an International Diabetes Federation (IDF) position statement presented by leading experts at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes in New York.
Scientists are reporting for the first time that nicotine is the main culprit in diabetes complications among smokers. The tobacco chemical appears to cause elevated levels of a blood protein that increases the risk of diabetes complications, including heart attack, stroke, and blindness, the scientists say. Scientists will describe the finding at the 241st National Meeting of the American Chemical Society in Anaheim.
The International Diabetes Federation (IDF) will hold a press briefing to announce their first position statement on interventional therapies for Type 2 diabetes.
Researchers at UT Southwestern Medical Center have discovered a hormone pathway that potentially could lead to new ways of treating type 1 diabetes independent of insulin, long thought to be the sole regulator of carbohydrates in the liver.
New evidence has emerged from studies in mice that short telomeres or “caps” at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists.
People with type 1 diabetes, whose insulin-producing cells have been destroyed by the body’s own immune system, are particularly vulnerable to a form of inflammatory heart disease caused by a different autoimmune reaction. Scientists at Joslin Diabetes Center now have revealed the exact target of this other onslaught.
A daily dose of safflower oil, a common cooking oil, for 16 weeks can improve such health measures as good cholesterol, blood sugar, insulin sensitivity and inflammation in obese postmenopausal women who have Type 2 diabetes, according to new research.
Americans consume more than 22 teaspoons of sugar daily - half is through sweetened beverages but the new beverage labeling initiative may show consumers how to stop being "sickeningly sweet."
On March 28, leading experts across multiple disciplines will convene at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes to review the latest research on bariatric surgery as a treatment option. The three-day meeting, hosted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City, will bring together physicians, scientists and policymakers representing 60 countries. The Congress director is Dr. Francesco Rubino, one of the world's leading authorities on bariatric surgery for diabetes.
Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process.
An inexpensive type 2 diabetes drug that has been around for more than 15 years works just as well and has fewer side effects than a half-dozen other, mostly newer and more expensive classes of medication used to control the chronic disease, new Johns Hopkins research suggests.
Scientists, physicians, and other health care practitioners are gathering in Doha to present and share the latest scientific research on the causes and treatment of diabetes, obesity and the metabolic syndrome at the XVII International DALM Symposium hosted by Qatar Foundation and Weill Cornell Medical College in Qatar and the Giovanni Lorenzini Medical Foundation in Milan, Italy and Houston, Texas.
New research may be relevant to how a mother’s diet during pregnancy influences obesity in her children. Rats fed a high-fat prenatal diet had offspring that were obese, an effect prevented by prenatal antixodidants.
The Stony Brook University School of Dental Medicine is leading a multicenter National Institutes of Health-sponsored clinical trial to evaluate whether treatment of chronic periodontitis will help improve diabetes control.
It has been thought that the quality of the physician-patient relationship is integral to positive outcomes but until now, data to confirm such beliefs has been hard to find. Through a landmark study, a research team from Jefferson Medical College (JMC) of Thomas Jefferson University has been able to quantify a relationship between physicians’ empathy and their patients’ positive clinical outcomes, suggesting that a physician’s empathy is an important factor associated with clinical competence. The study is available in the March 2011 issue of Academic Medicine.
Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer’s disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.
Two-thirds of people with diabetes have high blood pressure. Jenna L. Marquard of the University of Massachusetts Amherst is part of a research team developing a home blood pressure test for diabetics that sends the readings automatically to nurses so their medication can be adjusted as needed.
Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.
Insurers and consumers spent $52.2 billion on prescription drugs in 2008 for outpatient treatment of metabolic conditions such as diabetes and elevated cholesterol.
Despite significant advances in kidney care over the past 20 years, efforts to improve therapy for type 1 diabetes patients with kidney dysfunction remain unsuccessful, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that more effective therapies are needed for these patients.
Researchers at the University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego say an evolutionary gene mutation that occurred in human millions of years ago and our subsequent inability to produce a specific kind of sugar molecule appears to make people more vulnerable to developing type 2 diabetes, especially if they’re overweight.
A research team, led by La Jolla Institute scientist Joel Linden, Ph.D., has shed new light on the problem of insulin resistance, and identified the key participants in a molecular pathway that holds therapeutic promise for reducing the severity of type 2 diabetes.
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) found that individuals with fatty liver were five times more likely to develop type 2 diabetes than those without fatty liver. This higher risk seemed to occur regardless of the patient’s fasting insulin levels, which were used as a marker of insulin resistance.
A recent study accepted for publication in Endocrinology, a publication of The Endocrine Society, reports for the first time that maternal fructose intake during pregnancy results in sex-specific changes in fetal and neonatal endocrinology.
As childhood obesity rises, more attention is being given to testing children for diabetes. But which test is best for diagnosing diabetes in kids? A University of Michigan C.S. Mott Children's Hospital study shows a popular, convenient blood test is not the best option for diagnosing diabetes in children.
Researchers from Mount Sinai School of Medicine have discovered a novel function of brain insulin, indicating that impaired brain insulin action may be the cause of the unrestrained lipolysis that initiates and worsens type 2 diabetes in humans.
Examining people across the spectrum of type 2 diabetes—from healthy to the full-blown disease—Joslin Diabetes Center scientists have found a molecular pathway that offers novel targets for drugs.