Obese mice with unhealthy lifestyles gain significantly less weight and avoid type 2 diabetes when they receive viruses transplanted from the stool of lean mice. These are the findings of a new University of Copenhagen study.
The rate of heart attacks, strokes and other cardiovascular complications has improved among people with diabetes over the past 20 years, narrowing the gap in cardiovascular mortality rates between individuals with and without diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Older men who have lower lean body mass as they age are more prone to developing diabetes, while similar findings were not found in older women, according to a new study published in Journal of the Endocrine Society.
Short-term cold exposure may help people with brown fat burn 15 percent more calories than those without, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The website addresses the need for credible information and a plan to support families with children at home. Health care providers, graduate, and undergraduate students quickly developed a website that serves as a comprehensive single source for high quality COVID-19 customized for families who have a child living with diabetes.
Wake Forest School of Medicine, in partnership with University of North Carolina School of Medicine (UNC), Duke University School of Medicine and North Carolina Agricultural and Technical State University (NC A&T), has been awarded a $5.7 million Diabetes Research Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health (NIH).
High-altitude adaptations in the Himalayas may lower risk for some chronic diseases, according to a research team including faculty from Binghamton University, State University of New York, the University of New Mexico, and the Fudan University School of Life Sciences.
Researchers at Washington University School of Medicine in St. Louis have used induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes, transformed the stem cells into insulin-producing cells, used the CRISPR gene-editing tool to correct a defect that caused a form of diabetes, and implanted the cells into mice to reverse diabetes in the animals.
ADCES launches redesigned member platform
A new review suggests that higher-than-normal levels of an enzyme involved in blood clot prevention may be a common risk factor for developing COVID-19—a respiratory disease caused by the novel coronavirus SARS-CoV-2—in some populations. The review is published in Physiological Reviews.
Individuals with diabetes are at increased risk for bacterial, parasitic and viral infections. New research published in Endocrine Reviews, a journal of the Endocrine Society, illuminates how intersections of the coronavirus infection (COVID-19) and type 2 diabetes may require new approaches in treatment for hospitalized patients.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday, throughout the duration of the outbreak.
The behavior of previous coronaviruses together with physiological characteristics of diabetes may help explain why people with diabetes have a higher risk of developing COVID-19, a respiratory disease caused by the novel coronavirus SARS-CoV-2.
Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide. Even in children the numbers are overwhelming, with up to 80 percent of pediatric patients who are considered obese affected worldwide. People with NAFLD can progress to a severe form known as nonalcoholic steatohepatitis (NASH), which puts patients at higher risk for cirrhosis or liver cancer.
There's a higher case fatality rate in type 1 than type 2 diabetes, which suggests different mechanisms for heart failure might be involved in type 1 diabetes.” Given the burden of heart failure in type 1 diabetes, the early identification of patients at particular risk is of importance.
Joslin researchers have found a pathway that can boost the production of (heat-generating, fat-burning) brown fat cells without also creating unhelpful white fat cells. This finding suggests that the pathway the Joslin team uncovered might offer a solution to that challenge.
Doctors need to pay particular attention to patients with endocrine disorders and diabetes mellitus in relation to COVID-19 infections, say leading endocrinologists.
Houston Methodist nanomedicine researchers are studying a new drug delivery system that transports oral medication via triglycerides that could eliminate the need for injections or IV treatments of some biologic drugs for rheumatoid arthritis and other autoimmune diseases. They’re doing this with a diabetes drug that resulted in approximately 25% absorption in mice models, considered very high for an oral drug. The research will appear in Science Advances April 1.
The framework for the AADE7 Self-Care Behaviors were recently published, highlighting changes in diabetes care and management.
Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Obese females that ate a small amount of coconut oil daily, even as part of a high-fat diet, had decreased features of metabolic syndrome, a cluster of risk factors that raise the chances of developing diabetes, heart disease and stroke, an animal study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society.
Adults with type 2 diabetes requiring insulin therapy can safely achieve good blood sugar control using regular human insulin (RHI) in a wearable, patch-like insulin delivery device called V-Go®, a new study finds. Results of the randomized controlled study—which was accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society—suggest “a more affordable option” for insulin therapy than newer insulin types, the researchers said.
Continuous glucose monitor (CGM) and continuous subcutaneous insulin infusion (CSII) devices are known to improve outcomes in patients with type 1 diabetes (T1D), yet African American and Hispanic patients face barriers to the use of these devices, according to results of a small single-center retrospective study. The results of the ENDO 2020 abstract will be published in the Journal of the Endocrine Society.
Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
A type of artificial intelligence called machine learning can help predict which patients will develop diabetes, according to an ENDO 2020 abstract that will be published in a special supplemental section of the Journal of the Endocrine Society.
Scientists at St. Jude Children’s Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.
In patients with diabetes, loss of the gland that helps lubricate the eye may be a sign of elevated blood glucose levels, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The study will be published in the Journal of the Endocrine Society.
Patients with type 1 diabetes who use Medtronic’s MiniMedTM 670G insulin pump system are able to maintain blood glucose levels in the targeted range over 71% of the time, according to a study that analyzed some 6 million days of real-world data. Results of the industry-supported study were accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and will be published in a special supplemental issue of the Journal of the Endocrine Society.
Obese patients may lose more weight if they undergo bariatric surgery before they develop diabetes, suggests a study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The research will be published in a special supplemental issue of the Journal of the Endocrine Society.
Better glucose control can help people with diabetes who have a common type of stroke to preserve their cognitive function, according to a study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The abstract will be published in a special supplemental issue of the Journal of the Endocrine Society.
The international medical team that accomplished the world’s first documented drone delivery of insulin for a patient living in a remote community described the project in an ENDO 2020 abstract that will be published in the Journal of the Endocrine Society.
Patients with poorly controlled type 2 diabetes who underwent a novel, minimally invasive, endoscopic procedure called Revita® duodenal mucosal resurfacing (DMR) had significantly improved blood glucose (sugar) levels, liver insulin sensitivity, and other metabolic measures three months later, according to new data from the REVITA-2 study.
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows.
Researchers from the University of California, Irvine have conducted a statistical analysis that predicts more than 70,000 heart attacks, strokes and other adverse cardiovascular events could be prevented each year in the U.S. through the use of a highly purified fish oil therapy.
Researchers at Notre Dame found that individuals going to bed even 30 minutes later than their usual bedtime presented a significantly higher resting heart rate that lasted into the following day.
The following are various story ideas regarding the COVID-19 illness. To interview Johns Hopkins experts on these topics or others, contact [email protected].
Researchers will discuss how artificial intelligence and drones are being incorporated into health care when they share the latest emerging science during the Endocrine Society’s ENDO 2020 virtual news conferences March 30-31.
James Ellor, Ph.D., The Dorothy Barfield Kronzer Endowed Professor in Baylor University’s Diana R. Garland School of Social Work, is an expert on working with older adults as well as disaster behavioral health. He said it’s important in this time of uncertainty to continue to support and minister to those older adults who are self-isolating in their homes and those in long-term care facilities.
Now, as part of an effort to reduce the rate of patients with diabetic kidney disease who develop kidney failure, researchers at Penn Medicine are spearheading a collaboration to better understand the progression of DKD and advance research aimed at preserving kidney function in these patients.
blood and tissue samples from 40 patients suffering from severe obesity taken during bariatric surgery were used. Half of the participants suffered from type 2 diabetes, while the other subjects showed insulin resistance without being diabetic. The researchers identified the bacterial genetic material in each of the tissues sampled, which came from the liver and three abdominal fat deposits. Based on the type of bacteria present and their relative abundance, the researchers were able to determine the bacterial signature for each tissue.
A study by researchers at Mayo Clinic in Arizona published in the The Journal of Clinical Investigation has found that obesity is not only implicated in chronic diseases such as diabetes, but also in sudden-onset diseases such as pancreatitis.
Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.
Diabetic retinopathy can be diagnosed and graded with the use of a newer scanning technology called ultra-wide field (UWF) imaging, a system that generates high-quality pictures showing most of the retina. Research from the Joslin Diabetes Center’s Beetham Eye Institute has now shown that one technique, UFW fluorescein angiography, detects over three times more microaneurysms than UWF color imaging
The Online First edition of the upcoming April issue of The Lancet, one of the world’s leading medical journals, features an article on Health People’s new diabetes report, “Wasted Billions, Wasted Health.” (https://tinyurl.com/r4mcgrz)
Older people who experience daytime sleepiness may be at risk of developing new medical conditions, including diabetes, cancer and high blood pressure, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto, Canada, April 25 to May 1, 2020.
A study of beverage sales in Cook County, Illinois, shows that for four months in 2017 — when the county implemented a penny-per-ounce tax on both sugar-sweetened and artificially sweetened drinks — purchases of the taxed beverages decreased by 21%, even after an adjustment for cross-border shopping.
The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells.
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