Feature Channels: Autoimmune Diseases

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La encefalitis causada por el ataque del sistema inmunitario al cerebro tiene una frecuencia similar a la de la encefalitis producto de infecciones, informan los investigadores de Mayo Clinic en los Anales de Neurología.

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ROCHESTER, Minn. — Encephalitis caused by the immune system attacking the brain is similar in frequency to encephalitis from infections, Mayo Clinic researchers report in Annals of Neurology.

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When the body attacks its own healthy tissues in an autoimmune disease, peripheral nerve damage handicaps people and causes persistent neuropathic pain when insulation on healing nerves doesn’t fully regenerate. Unfortunately, there are no effective ways to treat the condition. Now scientists describe in Nature Medicine an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort.

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VF Bob is a new campaign launched by the Vasculitis Foundation to honor the late Bob Sahs, one of the organization's greatest awareness advocates. The goal of the campaign is to both spread awareness about autoimmune vasculitis, and to promote the work of the Vasculitis Foundation to support patients and fund research into vasculitis.

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The ACR urged HHS to reform its prior authorization policies, to reverse a recent HHS decision to apply Part B drug spending to payment adjustments under the Merit-Based Incentive Payment System (MIPS); require pharmacy benefit managers (PBMs) to be more transparent; and continue supporting biosimilar innovation.

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Loyola's Pauline Camacho, MD, Offers Tips for National Thyroid Awareness Month

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The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades.

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Mount Sinai Doctors Stress Importance of Early Detection and Announce Expansion of Thyroid Services in NYC

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UT Southwestern Medical Center researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.

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Duke Health researchers, publishing in the Jan. 4 issue of the New England Journal of Medicine, found significantly improved survival among patients with a severe form of scleroderma who underwent chemotherapy, whole body radiation and a stem cell transplant. Patients also had less need for immune suppressant drugs after transplant.

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Helper T cells move toward inflamed tissue using membrane protrusions that stabilize them and provide traction on the vasculature. Using high-resolution microscopy and global molecular analysis, the team shows that immature T cells lack these protrusions but that maturing T-cells switch on a gene expression program to create material to construct them.

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The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented the Winter Rheumatology Symposium in Snowmass Village, CO on January 20-26, 2018.

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New findings uncover the mechanisms by which gut bacteria can trigger inflammation in the brain and contribute to multiple sclerosis

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EASTPOINTE, MI – NOVEMBER 20, 2017: American Autoimmune Related Diseases Association (AARDA) presents “What Every American Needs to Know About Autoimmune Disease” public forum Saturday, December 9, 2017. This FREE conference is open to patients, their families, healthcare providers and the public. The forum will take place at Second Ebenezer Church located at 14601 Dequindre Road, Detroit, MI 48212. Registration begins at 9:30 am and the program is 10:00 a.m. - 2:30 p.m. Free lunch will be provided to registered attendees.

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University of Colorado Boulder researchers have developed a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases.

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.

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American Autoimmune Related Diseases Association (AARDA) has joined #GivingTuesday, a global day of giving that harnesses the collective power of individuals, communities, and organizations to encourage philanthropy and to celebrate generosity worldwide.

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EULAR & ACR will present the draft of new classification criteria for systemic lupus erythematosus (SLE) during a session at the 2017 ACR/ARHP Annual Meeting this week in San Diego, California, at the San Diego Convention Center.

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Authors of the new American College of Rheumatology (ACR) / National Psoriasis Foundation (NPF) treatment guideline for psoriatic arthritis (PsA) will present their draft recommendations during a session at the 2017 ACR/ARHP Annual Meeting this week in San Diego.

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ACR announced the 2017 recipients of its Master of the ACR designation, Awards of Distinction, and Distinguished Fellow Award honors during the opening lecture of the 2017 ACR/ARHP Annual Meeting in San Diego.

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Higher intake of omega-3 fatty acids was associated with better sleep quality and a decrease in depressive symptoms in lupus patients, among other patient-reported outcomes, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Obese patients with axial spondyloarthropathy have worse disease outcomes, including higher disease activity, worse physical function and lower quality of life, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Adherence to lupus therapy may be lower among Medicaid beneficiaries who live in areas with higher proportions of African-American individuals, fewer hospitals and less access to health professionals, according to new research findings presented at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Rheumatoid arthritis patients in remission may experience more successful tapering of their biologic drugs if they meet a certain set of factors, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Extracorporeal shock-wave therapy at low energy levels showed promise as a new treatment for digital ulcers in patients with systemic sclerosis, or scleroderma, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Low levels of vitamin D were associated with higher rates of end-stage renal disease in patients with systemic lupus erythematosus, or lupus, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Excess weight is linked to a higher degree of synovitis in people with rheumatoid arthritis and can affect their treatment response, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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While MRI scans of the sacroiliac joints positive for inflammation are not always specific in patients with axial spondyloarthritis (axSpA), their prevalence in healthy individuals demonstrates the importance of additional diagnostic measures for axSpA.

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Patients with rheumatoid arthritis whose body-mass index scores are higher have lower rates of remission and higher rates of disability, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Using a biologic therapy to manage rheumatoid arthritis may not significantly increase an infant’s risk for developing opportunistic infections like pneumonia, meningitis, and tuberculosis, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Opioids and selective serotonin reuptake inhibitors, a widely used group of antidepressants, are both associated with higher risk of osteoporotic fractures for patients with rheumatoid arthritis, according to new research findings presented at the 2017 ACR/ARHP Annual Meeting in San Diego.

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People with RA who stop taking methotrexate treatment for just two weeks after they have a seasonal flu shot can improve the vaccine’s efficacy without increasing RA disease activity, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Obesity is independently associated with worse patient-reported outcomes in women with systemic lupus erythematosus, including disease activity, depressive symptoms, pain and fatigue, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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An internet-based health education and self-management program that offers monthly calls with health coaches improved health-related quality of life for participating teens with juvenile idiopathic arthritis, according to research presented at the 2017 ACR/ARHP Annual Meeting in San Diego.

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A large percentage of patients with end-stage knee, hip and spine osteoarthritis use opioids to manage their chronic pain, especially those who are younger or have symptoms of depression, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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A new method for acquiring viable cells from cryopreserved tissue samples could provide researchers with a model for collecting and analyzing samples from different study sites to conduct more centralized research.

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Women who took a drug holiday from using bisphosphonates for more than two years have a significantly higher risk of a hip fracture compared to others who continued their treatment, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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A newly developed tool to analyze the cellular and molecular profiles of synovial tissue and peripheral blood may help unlock clues about rheumatoid arthritis and lead to better therapies, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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MRI scans of healthy military recruits showed sacroiliac joint damage similar to that found in axial spondyloarthritis after six weeks of intensive physical training, reinforcing the importance of exercising caution when interpreting MRI results.

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Quality measures reported by rheumatology practices using the RISE registry significantly varied in the first quarter of 2017, with financial repercussions for practices through the new Merit-Based Incentive Payment System (MIPS), according to research presented at the 2017 ACR/ARHP Annual Meeting.

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A 12-week, digital health coaching program with personalized support from a dedicated health coach improved well-being and decreased symptoms for participants with rheumatoid arthritis, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

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Researchers in China have developed a new online consultation tool for rheumatic disease patients, which may strengthen the interaction between doctors and patients and lead to more efficient management of chronic illness.

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Actors, singer-songwriters, musicians and others lend their talents to help end autoimmune disease

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Scientists understand new details about the development of Th17, a type of immune cell that is believed to play a complex role in cancer, and is also implicated in autoimmune diseases.

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When most people think of arthritis, they picture the knobby knuckles, inflamed joints or aching back of an older person. But more than 300,000 children suffer from chronic juvenile idiopathic arthritis.

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Jamey Marth, Ph.D., professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), is the 2017 recipient of the Society for Glycobiology’s Karl Meyer Award. The international award is given to well-established scientists with currently active research programs who have made widely recognized major contributions to the field of glycobiology. Marth is also the Carbon Professor of Biochemistry and Molecular Biology, Mellichamp Professor of Systems Biology, and Director of the Center for Nanomedicine at UC Santa Barbara.

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Four multidisciplinary studies will focus on genetics and associated mechanisms of hyperuricemia gout, an inflammatory arthritis.

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Approximately seven out of 10 Michigan consumers have an unfavorable view of a health insurance company tactic called “step therapy,” according to a new poll conducted by Lake Research Partners. Ninety-five percent of respondents believe that a doctor, not an insurance company, should have final say in how to best treat a patient.

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Using an influenza infection model in mice, researchers find a particular population of immune cells develops during the later stages of the immune response to the influenza. These cells, called T follicular regulatory cells, prevent the generation of self-reactive antibody responses.