Curated News: National Eye Institute (NEI)

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Released: 27-Jul-2021 9:30 AM EDT
Scientists Uncover How Decisions About What We See Are Relayed Back Through the Brain
NIH, National Eye Institute (NEI)

Researchers at the National Institutes of Health have discovered that decisions based on visual information, which involve a complex stream of data flowing forward and backwards along the brain’s visual pathways, is broadcast widely to neurons in the visual system, including to those that are not being used to make the decision.

19-Jul-2021 2:35 PM EDT
Scientists Discover Gene Therapy Provides Neuroprotection to Prevent Glaucoma Vision Loss
NIH, National Eye Institute (NEI)

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness.

19-Jul-2021 2:35 PM EDT
Scientists Discover Gene Therapy Provides Neuroprotection to Prevent Glaucoma Vision Loss
NIH, National Eye Institute (NEI)

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness.

19-Jul-2021 9:25 AM EDT
Gene Therapy May Preserve Vision in Retinal Disease and Serious Retinal Injury
Mount Sinai Health System

Mount Sinai researchers uncover a potential pathway for treatment that can prevent blindness

Released: 30-Jun-2021 11:55 AM EDT
Dry Eye Awareness Month 2021 Focuses on a Looming Lifestyle Epidemic—Ocular Surface Disease
Association for Research in Vision and Ophthalmology (ARVO)

The vision community and its coalition partners announce awareness and educational activities in July 2021 around the annual recognition of Dry Eye Awareness Month.

Released: 21-Jun-2021 9:45 AM EDT
NIH-Funded Study Shows Children Recycle Brain Regions When Acquiring New Skills
NIH, National Eye Institute (NEI)

Scientists studied the brain activity of school-aged children during development and found that regions that activated upon seeing limbs (hands, legs, etc.) subsequently activated upon seeing faces or words when the children grew older. The research, by scientists at Stanford University, Palo Alto, California, reveals new insights about vision development in the brain and could help inform prevention and treatment strategies for learning disorders. The study was funded by the National Eye Institute and is published in Nature Human Behaviour.

Released: 21-Jun-2021 9:45 AM EDT
NIH-Funded Study Shows Children Recycle Brain Regions When Acquiring New Skills
NIH, National Eye Institute (NEI)

Scientists studied the brain activity of school-aged children during development and found that regions that activated upon seeing limbs (hands, legs, etc.) subsequently activated upon seeing faces or words when the children grew older. The research, by scientists at Stanford University, Palo Alto, California, reveals new insights about vision development in the brain and could help inform prevention and treatment strategies for learning disorders. The study was funded by the National Eye Institute and is published in Nature Human Behaviour.

Released: 16-Jun-2021 4:05 PM EDT
Scientists unravel the function of a sight-saving growth factor
NIH, National Eye Institute (NEI)

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD).

Released: 16-Jun-2021 4:05 PM EDT
Scientists unravel the function of a sight-saving growth factor
NIH, National Eye Institute (NEI)

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD).

14-Jun-2021 5:20 PM EDT
What makes us sneeze?
Washington University in St. Louis

What exactly triggers a sneeze? A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex. Better understanding of what causes us to sneeze — specifically how neurons behave in response to allergens and viruses — may point to treatments capable of slowing the spread of infectious respiratory diseases.

Released: 25-May-2021 9:20 AM EDT
Case Western Reserve-led research team aims to determine which diabetic individuals can successfully donate corneas for transplant (and which should not)
Case Western Reserve University

In a new study, supported by a five-year, $6.4 million grant from the National Eye Institute of the National Institutes of Health, researchers from Case Western Reserve University, University Hospitals and the Jaeb Center for Health Research, aim to finally determine which diabetic individuals can successfully donate their corneas for keratoplasty (and which should not).

Released: 22-Apr-2021 2:15 PM EDT
Audacious projects develop imaging technology to aid eye tissue regeneration
NIH, National Eye Institute (NEI)

As regenerative therapies for blinding diseases move closer to clinical trials, the National Eye Institute’s functional imaging consortium, a part of the NEI Audacious Goals Initiative (AGI), is pioneering noninvasive technologies to monitor the function of the retina’s light-sensing neurons and their connections to the brain.

Released: 13-Apr-2021 1:15 PM EDT
An Artificial Retina Engineered From Ancient Protein Heads to Space
NIH, National Eye Institute (NEI)

NIH supported early testing of the artificial retina. Now, scientists are testing whether manufacturing it on the International Space Station results in a viable treatment for people with blinding eye diseases.

26-Mar-2021 12:00 PM EDT
Preventive treatment reduces diabetic retinopathy complications
NIH, National Eye Institute (NEI)

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which usually begins at the onset of late disease.

26-Mar-2021 12:00 PM EDT
Preventive treatment reduces diabetic retinopathy complications
NIH, National Eye Institute (NEI)

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which usually begins at the onset of late disease.

Released: 18-Mar-2021 9:35 AM EDT
National Eye Institute launches data portal for macular degeneration research
NIH, National Eye Institute (NEI)

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2). The database complements newly available stem cell lines created by the New York Stem Cell Foundation Research Institute (NYSCF) from blood cells of AREDS2 study participants.

22-Feb-2021 3:20 PM EST
International Team Identifies 127 Glaucoma Genes in Largest Study of Its Kind
Massachusetts Eye and Ear

In the largest genome-wide association study of glaucoma to date, an international team of researchers compared the genes of 34,179 people with the disease to 349,321 control subjects. They identified 127 genes linked to glaucoma, including 44 new gene loci and confirmed 83 previously reported loci.

Released: 11-Feb-2021 1:45 PM EST
Johns Hopkins Scientists Find Mammals Share Gene Pathways That Allow Zebrafish To Grow New Eyes
Johns Hopkins Medicine

Working with fish, birds and mice, Johns Hopkins Medicine researchers report new evidence that some animals’ natural capacity to regrow neurons is not missing, but is instead inactivated in mammals. Specifically, the researchers found that some genetic pathways that allow many fish and other cold-blooded animals to repair specialized eye neurons after injury remain present in mammals as well, but are turned off, blocking regeneration and healing.

   
Released: 11-Feb-2021 8:05 AM EST
Cold sores: Discovery reveals how stress, illness and even sunburn trigger flareups
University of Virginia Health System

The finding could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report.

25-Jan-2021 4:10 PM EST
Researchers use patients’ cells to test gene therapy for rare eye disease
NIH, National Eye Institute (NEI)

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood. A form of Leber congenital amaurosis, the disease is caused by autosomal-dominant mutations in the CRX gene, which are challenging to treat with gene therapy.



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