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National Center for Advancing Translational Sciences (NCATS)

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Adrenaline Handbrake

Harvard Medical School

Researchers have solved the long-standing mystery of how adrenaline regulates a key class of membrane proteins that are responsible for initiating the contraction of heart cells. The findings provide a mechanistic description of how adrenaline stimulates the heart and present new targets for cardiovascular drug discovery, including the potential development of alternative therapeutics to beta-blockers.

Channels: All Journal News, Cardiovascular Health, Cell Biology, Pharmaceuticals, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Nature (journal),

23-Jan-2020 12:05 PM EST