Curated News: National Institute of Neurological Disorders and Stroke (NINDS)

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Newswise: Releasing Brakes: Potential New Methods for Duchenne Muscular Dystrophy Therapies
Released: 24-Feb-2020 12:10 PM EST
Releasing Brakes: Potential New Methods for Duchenne Muscular Dystrophy Therapies
Perelman School of Medicine at the University of Pennsylvania

Testing of small molecules in mouse models of Duchenne muscular dystrophy shows promise for restoration of muscle structure and function.

Newswise: Fetal Balloon Treatment for Lung-Damaging Birth Defect Works Best When Fetal and Maternal Care Are Highly Coordinated
Released: 19-Feb-2020 10:00 AM EST
Fetal Balloon Treatment for Lung-Damaging Birth Defect Works Best When Fetal and Maternal Care Are Highly Coordinated
Johns Hopkins Medicine

Researchers from The Johns Hopkins Center for Fetal Therapy report new evidence that fetuses with severe congenital diaphragmatic hernia (CDH), a rare but life-threatening, lung-damaging condition, experience a significantly high rate of success for the fetal treatment known as FETO, if they and their mothers receive coordinated and highly experienced care in the same expert setting.

Newswise: The Human Brain’s Meticulous Interface with the Bloodstream now on a Precision Chip
Released: 10-Feb-2020 11:30 AM EST
The Human Brain’s Meticulous Interface with the Bloodstream now on a Precision Chip
Georgia Institute of Technology

It can be the bain of brain drug developers: The interface between the human brain and the bloodstream, the blood-brain-barrier, is so meticulous that animal models often fail to represent it. This improved chip represents important features more accurately.

Newswise: Study: Two Enzymes Control Liver Damage in NASH
Released: 4-Feb-2020 1:40 PM EST
Study: Two Enzymes Control Liver Damage in NASH
University of California San Diego Health

After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.

Released: 3-Feb-2020 10:20 AM EST
Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s
Georgia Institute of Technology

The promise of flickering light to treat Alzheimer's takes another step forward in this new study, which reveals stark biochemical mechanisms: The 40 Hertz stimulation triggers a marked release of signaling chemicals.

Released: 28-Jan-2020 6:50 PM EST
Stem Cells, CRISPR and Gene Sequencing Technology are Basis of New Brain Cancer Model
University of California San Diego Health

University of California San Diego School of Medicine researchers created a new type of brain cancer model for glioblastoma using stem cells, CRISPR and gene sequencing.

Newswise: Scientists Find Molecular Key to Body Making Healthy T Cells
Released: 24-Oct-2019 11:05 AM EDT
Scientists Find Molecular Key to Body Making Healthy T Cells
Cincinnati Children's Hospital Medical Center

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

Newswise: Brain Studies Show Chronic Fatigue Syndrome and Gulf War Illness are Distinct Conditions
Released: 18-Oct-2019 1:55 PM EDT
Brain Studies Show Chronic Fatigue Syndrome and Gulf War Illness are Distinct Conditions
Georgetown Lombardi Comprehensive Cancer Center

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise). Now, neuroscientists at Georgetown University Medical Center have evidence, derived from human brain studies, that GWI and CFS are two distinct disorders that affect the brain in opposing ways.

Newswise: “Metabolic Inhibitor” Compound Extends Survival in Mice with MYC-Expressing Pediatric Brain Tumors
Released: 23-Sep-2019 9:00 AM EDT
“Metabolic Inhibitor” Compound Extends Survival in Mice with MYC-Expressing Pediatric Brain Tumors
Johns Hopkins Medicine

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

Newswise: Wired to Think
Released: 23-Sep-2019 4:35 AM EDT
Wired to Think
University of California San Diego

UC San Diego research supplies a blueprint for a future generation of electrode sensors—notably microscopically slender diamond needles—that utilizes existing yet nontraditional materials and fabrication procedures for recording electrical signals from every neuron in the cortex at the same time.



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