Women with long or irregular periods are known to have a higher risk of type 2 diabetes and heart disease, but researchers found these women may also be at risk for nonalcoholic fatty liver disease (NAFLD), according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism.
Exercise may help certain patients with nonalcoholic fatty liver disease reduce their risk of developing blood clots, according to a new study by Penn State College of Medicine researchers.
In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body’s organs and increases the risk of early death from heart or liver disease. In 2001, a transmembrane protein called seipin was identified as a molecule essential for proper fat storage, although its mechanism has remained unknown.
The livers of men diagnosed with hepatic diseases change sex as part of a potential self-protective mechanism, according to University of Queensland research.
The Latest Research News in Cardiovascular Health
Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease. The discovery can also help lead to a new treatment approach for people suffering from the disease.
Researchers at Henry Ford Health System, as part of a national hepatitis C collaborative, report that patients with chronic hepatitis C who are treated with direct-acting antiviral medicines are less likely to be hospitalized or seek emergency care for liver and non-liver related health issues. The study, published online in Clinical Infectious Diseases, underscores the extraordinary effect of these newer antivirals, which have been shown to cure hepatitis C in 98 percent of patients who take them. Patients are said to be cured when the virus is no longer detectable in their blood.
Pacientes com cirrose relacionada ao consumo de álcool (ALC) têm piores resultados após receberem alta do tratamento intensivo, em comparação aos pacientes com cirrose associada a outras causas, de acordo com a nova pesquisa da Mayo Clinic.
Los resultados de los pacientes con cirrosis por alcohol (ALC, por sus siglas en inglés) después de recibir el alta de cuidados intensivos son peores que los de los pacientes con cirrosis por otras causas, dice un nuevo estudio de Mayo Clinic.
根据妙佑医疗国际(Mayo Clinic) 的新研究，相比其他病因的肝硬化患者，酒精性肝硬化（ALC）患者从重症监护室出院后的恢复结局较差。
ولاية مينيسوتا- يعاني مرضى تشمع الكبد المرتبط بالكحول من نتائج أسوأ بعد الخروج من العناية المركزة، مقارنةً بمرضى تشمع الكبد المرتبط بأسباب أخرى، وفقًا لبحث جديد من مايو كلينك.
Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.
A new study at Children’s Hospital Los Angeles independently verified the value of a system that assesses hepatoblastoma risk in children. Hepatoblastoma is a rare childhood liver cancer, usually seen within the first three years of a child’s life with 50 to 70 cases occurring in the U.S. each year.
InSphero AG, the pioneer in 3D cell-based assay and organ-on-chip technology, today announced the strengthening of its Scientific Advisory Board (SAB) with the appointment of Professor Nikolai Naoumov, MD PhD.
In new research published in Liver International, researchers at Henry Ford Health System have found that people hospitalized for alcoholic hepatitis – a life threatening liver disease fueled by alcohol use – increased a staggering 50 percent in the early months of the COVID-19 pandemic. Researchers said the role of gender and race had no meaningful impact on the spike in admissions.
An imprinted gene associated with development of non-alcoholic fatty liver disease (NAFLD) is switched on in mice who nurse from mothers with metabolic syndrome, even when those mice are not biologically related.
Miral Sadaria Grandhi, MD, surgical oncologist in the Liver Cancer and Bile Duct Cancer Program at Rutgers Cancer Institute of New Jersey and assistant professor of surgery at Rutgers Robert Wood Johnson Medical School, shares more about gallbladder and bile duct cancer.
Diagnosed with acute liver failure and her health rapidly deteriorating, it seemed like 11-month-old Lennon would need a miracle to survive. Thanks to a team of specialists at Children’s Hospital Los Angeles, she just celebrated her third birthday.
The February issue of AJG includes new ACG Clinical Guidelines on acute-on-chronic liver failure, the College’s first set of guidelines on a condition that is emerging as a major cause of mortality among patients with cirrhosis and CLD.
Patients with alcohol-associated cirrhosis have poorer outcomes after ICU discharge, compared to patients with cirrhosis linked to other causes, according to new Mayo Clinic research.
Acute liver failure (ALF) happens very quickly, with few warning signs before a child presents in the emergency room. But there are also few reliable predictors of a child’s outcome. That makes it challenging for physicians to know when it’s best to move forward with a liver transplant—and when it’s best to wait.
Immunotherapy given before surgery caused liver cancer tumors to die off in one-third of the patients enrolled in a first-of-its-kind clinical trial, Mount Sinai researchers reported in The Lancet Gastroenterology & Hepatology in January.
A team of NUS researchers from Cancer Science Institute of Singapore has identified new pathways responsible for hepatocellular carcinoma (HCC), the most common type of primary liver cancer. The new insights could potentially improve treatment for patients.
Physician researchers from UT Southwestern Medical Center have developed an innovative nanotherapeutic drug that prevents cancer from spreading to the liver in mice.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include an anti-CD19 chimeric antigen receptor (CAR) T cell therapy to treat follicular lymphoma, targeted therapies for urothelial cancers and advanced breast cancers, understanding the tumor microenvironment and immune landscape in pancreatic cancer, a link between depression risk and androgen deprivation for prostate cancer, and the discovery of new therapeutic targets for Alzheimer’s disease, liver cancer and aggressive breast cancer.
The American College of Gastroenterology has just released new clinical guidelines on Acute-on-Chronic Liver Failure, an emerging major cause of mortality. The ACG Media Team can connect you with the authors or outside experts who can comment on the guidelines upon request.
A new study has shown that alcohol-related diseases are driven by both environmental and genetic factors, a proportion of which are not shared with the underlying alcohol use disorder (AUD).
UC San Diego researchers identify new strategy to improve efficacy of immunotherapy on resistant liver cancers.
The latest findings of a series of studies on mice that examined harmful effects caused by spending time in space show that gene expression related to liver metabolism is altered in response to the space environment.
Metabolic-associated fatty liver disease (MAFLD) is a growing global health challenge and poses a substantial economic burden.
The December issue of The American Journal of Gastroenterology is the final issue published under the leadership of Co-Editors-in-Chief Brian E. Lacy, MD, PhD, FACG, and Brennan M.R. Spiegel, MD, MSHS, FACG.
The December 2021 issue of Toxicological Sciences is now available and contains leading articles in the areas of developmental and reproductive toxicology, environmental toxicology, and more.
A UC Davis Health team has developed a new positron emission tomography (PET) scan imaging-based tool to detect liver inflammation in patients affected with non-alcoholic fatty liver disease. The condition affects nearly a third of the population of the United States.
The National Cancer Institute has awarded Mount Sinai researchers $3.15 million in grant funding to assess the potential of a multidisciplinary drug development platform to identify new biological targets for precision-based therapeutics for hepatocellular carcinoma (HCC). The platform includes precision mouse models, tumor 3D organoids, and a proprietary library of small molecule inhibitors.
RUDN University doctors examined markers of liver cancer and found that the disease can be recognized by RNA fragments in saliva and blood.
New imaging software designed by University of South Australia researchers can now detect jaundice - a potentially life-threatening condition in newborns - in one second, automatically start treatment, and notify a nurse by text.
ALEXANDRIA, Va. – A new study has found that the proportion of older Americans who need a liver transplant (LT) has sharply increased in recent years, often due to the rising number of cases of nonalcoholic steatohepatitis (NASH). As the U.S. population ages, researchers estimate that more patients aged 65 or older will need an LT than ever before.
ALEXANDRIA, Va. – New research has found that patients with nonalcoholic fatty liver disease (NAFLD) who have high blood iron levels are at an elevated risk to develop the most common type of liver cancer, hepatocellular carcinoma (HCC). Researchers at the University of Pittsburgh will present their findings this week at The Liver Meeting Digital Experience™ held by the American Association for the Study of Liver Diseases.
ALEXANDRIA, Va. – A new study has found that among patients with cirrhosis, a late-stage liver disease, almost one in five outpatient clinic visits involve an opioid prescription. The study, presented this week at The Liver Meeting Digital Experience™ held by the American Association for the Study of Liver Diseases, also suggests that most of the physicians who prescribe opioids for patients with cirrhosis are not gastroenterologists or hepatologists, raising concerns those physicians may be less familiar with the potentially harmful effects of opioid drugs in patients with liver disease.
ALEXANDRIA, Va. – A new study has found that people with nonalcoholic fatty liver disease (NAFLD) cirrhosis who are not overweight and are on a waiting list for a liver transplant fare worse than overweight patients before and after transplant surgery. The study concludes that these at-risk patients need better nutritional counseling and other interventions to help prevent serious health problems while they are waiting for liver transplant.
A Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric weight loss surgery significantly lowered their future risk of liver disease complications and serious cardiovascular disease compared with patients who did not have surgery.
A new Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric surgery (weight-loss surgery) significantly lowered their risk for severe liver disease and serious cardiovascular disease, including heart attack and stroke, compared to patients who did not have the surgery.
The Institute of Human Virology at the University of Maryland School of Medicine and MitoPower LLC were awarded an Small Business Innovation Research grant of $6.5 million from the NIH’s National Institute on Alcohol Abuse and Alcoholism to develop a treatment for alcoholic liver disease-associated hepatorenal syndrome.
The leading cause of HCV in the U.S. is injection drug use as a result of opioid use disorder (OUD), which has seen a rise in most populations, including pregnant people, in recent years. HCV rates have also risen. Between 2009 and 2019, the overall rate per 1,000 live births of HCV in pregnant people increased from 1.8 to 5.1.
Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.
Researchers report waiting list registrations and deceased donor liver transplants in the U.S. for alcoholic hepatitis, which can develop after a short period of alcohol misuse, increased during COVID-19, exceeding volumes forecasted by pre-COVID-19 trends, while trends for alcohol-related cirrhosis and non-alcohol-associated liver disease remained unchanged.
This special edition features oral presentations by MD Anderson researchers at the 2021 American Society for Radiation Oncology (ASTRO) Annual Meeting (Oct. 24-27) on novel therapeutic and diagnostic approaches, including partial breast irradiation, evaluating PD-L1 levels as biomarkers to better predict response to immunotherapy, and deep learning and biomechanical models.
People with liver cancer awaiting transplantation could benefit from non-invasive radiation treatments but are rarely given this therapy, according to a new analysis of U.S. national data. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.
A total of 64 Mercy Medical Center physicians were recognized in Baltimore magazine’s November 2021 “Top Doctors” issue, representing 48 separate specialties
RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis.
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