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Newswise: Preclinical Study Shows Targeted Drug Strengthens the Power of CAR T-Cell Therapy in Two Pediatric Leukemias
Released: 7-Dec-2024 7:00 PM EST
Preclinical Study Shows Targeted Drug Strengthens the Power of CAR T-Cell Therapy in Two Pediatric Leukemias
Roswell Park Comprehensive Cancer Center

A preclinical study led by a faculty member at Roswell Park Comprehensive Cancer Center shows that gilteritinib (brand name Xospata), a targeted cancer treatment, can strengthen chimeric antigen receptor (CAR) T-cell immunotherapy in two high-risk pediatric leukemias that have poor survival rates — FLT3-mutated acute myeloid leukemia (AML) and KMT2A-rearranged acute lymphoblastic leukemia (ALL). Lisa Niswander, MD, PhD, Assistant Professor of Oncology in the Department of Pediatric Oncology, will deliver the results this afternoon in an oral abstract session at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California.

Newswise: Roswell Park Study Reveals How Venetoclax Boosts Immune Response to CAR T for Chronic Lymphocytic Leukemia
7-Dec-2024 12:30 PM EST
Roswell Park Study Reveals How Venetoclax Boosts Immune Response to CAR T for Chronic Lymphocytic Leukemia
Roswell Park Comprehensive Cancer Center

Research out of Roswell Park Comprehensive Cancer Center has shed light on how the drug venetoclax (brand name Venclexta) works synergistically with CAR T-cell immunotherapy to combat chronic lymphocytic leukemia (CLL), the most common type of leukemia in the U.S. Matthew Cortese, MD, MPH, Assistant Professor of Oncology in Roswell Park’s departments of Medicine and Cancer Genetics & Genomics, is first author of the study, which he will present during an oral abstract session today at the 66th annual meeting of the American Society of Hematology (ASH) in San Diego, California.

5-Dec-2024 9:00 AM EST
Keto Diet Metabolite May Power Up CAR T Cells to Kill Cancer
Perelman School of Medicine at the University of Pennsylvania

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center, presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition (Abstract 4).

Newswise: New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Released: 7-Dec-2024 10:00 AM EST
New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Children's Hospital of Philadelphia

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented during the plenary session at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego on December 8.

Newswise: 1920_cedars-sinai-pharmacy-conference.jpg?10000
Release date: 6-Dec-2024 11:10 PM EST
Cedars-Sinai Pharmacists Attending Midyear Clinical Meeting 2024
Cedars-Sinai

Cedars-Sinai experts in pharmacy services attending the Dec. 8-12 American Society of Health-System Pharmacists (ASHP) Midyear Clinical Meeting 2024 in New Orleans are available for interviews about the latest developments in patient safety and pharmacy practice.

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Newswise: Thawing Permafrost Reveals Complex Microbiome–Metabolite Interplay
Released: 6-Dec-2024 5:50 PM EST
Thawing Permafrost Reveals Complex Microbiome–Metabolite Interplay
Environmental Molecular Sciences Laboratory - EMSL

Research led by a multi-institutional study found that microbes interact with sulfur- and nitrogen-rich compounds, possibly from mosses in bogs. This interaction appears to contribute to greenhouse gas production.

Released: 6-Dec-2024 5:50 PM EST
CSUF Among Top 5 National Institutions for Bachelor’s Degrees to Latinx Students
California State University, Fullerton

Cal State Fullerton ranked No. 4 in the nation among four-year schools for the total number of bachelor’s degrees awarded to Latinx students in both Hispanic Outlook in Higher Education’s 2024 “Top 100 Colleges and Universities for Hispanics” and Diverse: Issues In Higher Education’s 2024 “Top 100 Degree Producers” rankings.

   
Newswise: Illinois Research Illuminates Signal Transduction Mechanisms in Cys-loop Receptors
Released: 6-Dec-2024 5:10 PM EST
Illinois Research Illuminates Signal Transduction Mechanisms in Cys-loop Receptors
College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign

University of Illinois researchers discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the field of ion-channel physiology and contributing to rational drug design.

Newswise: How Caregivers of People With Dementia Can Navigate the Holidays
Released: 6-Dec-2024 4:25 PM EST
How Caregivers of People With Dementia Can Navigate the Holidays
Rutgers University-New Brunswick

Although the holiday season brings joy to many, it may mean added stress for those supporting a family member with memory loss. Mary-Catherine Lundquist, the program director of Care2Caregivers, a peer counseling helpline (800-424-2494) for caregivers of individuals with Alzheimer’s disease and related memory disorders operated by Rutgers Behavioral Health Care, discusses how families can make the most of the season.

Released: 6-Dec-2024 4:20 PM EST
Navigating the Holiday Season: MSU Experts Can Comment
Michigan State University

It’s the most wonderful time of the year, right? Not necessarily. We all know that the holidays can cause stress and angst as we cook, shop, entertain and spend time with family and friends we may not see often. Michigan State University experts offer suggestions on navigating the holiday — from the economy and food prices to religion and spirituality to health and relationships.

Newswise: Sacrificing Sleep During the Holiday Season
Released: 6-Dec-2024 4:15 PM EST
Sacrificing Sleep During the Holiday Season
American Academy of Sleep Medicine (AASM)

A new survey from the American Academy of Sleep Medicine reveals that more than half of Americans (55%) say they are extremely or somewhat tired during the holiday season.

Newswise: Researchers are Going to Map Cells Crucial to Child Respiratory Health and Disease
Released: 6-Dec-2024 3:50 PM EST
Researchers are Going to Map Cells Crucial to Child Respiratory Health and Disease
University of North Carolina School of Medicine

A research project co-led by researchers at the UNC School of Medicine and colleagues, will create an atlas of the cells in the nasal and oral cavities, throat, and lower airways of pediatric populations in unprecedented detail.

Newswise: VUMC to Study the Effect of Breathing Tube Size on Breathing, Speaking, Swallowing
Released: 6-Dec-2024 3:25 PM EST
VUMC to Study the Effect of Breathing Tube Size on Breathing, Speaking, Swallowing
Vanderbilt University Medical Center

Vanderbilt University Medical Center has been approved for $7 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to study the effect of breathing tube size on breathing, speaking and swallowing after critical illness.

Newswise: Calculation Sharpens Imaging of Protons’ Insides
Released: 6-Dec-2024 3:15 PM EST
Calculation Sharpens Imaging of Protons’ Insides
Department of Energy, Office of Science

Nuclear scientists used a new theoretical approach to calculate a value essential for unraveling the three-dimensional motion of quarks within a proton. The researchers obtained a significantly more accurate picture of these internal building blocks’ transverse motion. The work will aid in calculations of 3D motion of quarks and gluons in future collider experiments.

Newswise: Dark Energy Camera Spies the Outskirts of the Swirling Southern Pinwheel Galaxy
Released: 6-Dec-2024 3:00 PM EST
Dark Energy Camera Spies the Outskirts of the Swirling Southern Pinwheel Galaxy
NSF's NOIRLab

Twelve million light-years away lies the galactic masterpiece Messier 83, also known as the Southern Pinwheel Galaxy. Its swirling spiral arms display a high rate of star formation and have been host to six observed supernovae. This image was captured with the Department of Energy-fabricated Dark Energy Camera, mounted on the U.S. National Science Foundation Víctor M. Blanco 4-meter Telescope at Cerro Tololo Inter-American Observatory in Chile, a Program of NSF NOIRLab.

Newswise: Cerro Tololo registra un tesoro cósmico de estrellas nacientes y supernovas exclusivo de los cielos del Sur
Released: 6-Dec-2024 3:00 PM EST
Cerro Tololo registra un tesoro cósmico de estrellas nacientes y supernovas exclusivo de los cielos del Sur
NSF's NOIRLab

A 12 millones de años luz se encuentra la joya galáctica Messier 83, conocida también como la Galaxia del Molinillo Austral. Sus brazos espirales muestran una elevada tasa de formación estelar y además ya se han registrado seis supernovas observadas en ella. Esta detallada imagen se obtuvo en Chile con la Cámara de Energía Oscura del Departamento de Energía de los Estados Unidos, que se encuentra montada en el Telescopio de 4 metros Víctor M. Blanco, en Cerro Tololo, un Programa de NOIRLab de NSF.

Newswise: Three Sanford Burnham Prebys Faculty Members Ranked Among the World’s Most Influential Scientists
Released: 6-Dec-2024 2:45 PM EST
Three Sanford Burnham Prebys Faculty Members Ranked Among the World’s Most Influential Scientists
Sanford Burnham Prebys

Three faculty members at Sanford Burnham Prebys are among the most influential scientists worldwide in the 2024 rankings by the Institute for Scientific Information at Clarivate.

Newswise: NCCN Hosts Patient Advocacy Summit on Improving Access to Accurate Health Information
Released: 6-Dec-2024 2:00 PM EST
NCCN Hosts Patient Advocacy Summit on Improving Access to Accurate Health Information
National Comprehensive Cancer Network® (NCCN®)

NCCN hosts a Patient Advocacy Summit bringing together leading experts to promote strategies and best practices for improving cancer care, focused on practice and policy solutions for sharing accurate, evidence-based health information with patients and caregivers.

Newswise: UAlbany Chemists Develop Color-Changing Test for Rapid Salmonella Detection
Released: 6-Dec-2024 1:55 PM EST
UAlbany Chemists Develop Color-Changing Test for Rapid Salmonella Detection
University at Albany, State University of New York

UAlbany researchers have developed a new method for fast-acting salmonella detection. The test employs a paper strip that changes color in the presence of the bacterial genome, enabling quick, easy and inexpensive screening for salmonella in food products.



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