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Age-Related Macular Degeneration—Optometry and Vision Science Presents Research Update

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Recent years have seen major strides in basic science and clinical research on age-related macular degeneration (AMD)—the leading cause of vision loss in older adults. The August issue of Optometry and Vision Science, official journal of the American Academy of Optometry, is a theme issue devoted to advances and challenges in AMD research. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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The Medical Minute: Don’t Skimp on Shades This Summer

Sunscreen and sunglasses top the list of summertime must-haves for most people. But just as skin can burn on an overcast or chilly day, eyes can sustain damage anytime you’re outdoors without sunglasses.

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Gene Profiling Technique to Accelerate Stem Cell Therapies for Eye Diseases

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Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues. The technique will help the researchers in their efforts to use patients’ skin cells to regenerate retinal pigment epithelium (RPE)—a tissue in the back of the eye that is affected in several blinding eye diseases. It will also help the scientists search for drugs for personalized treatments.

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Acute Glaucoma Discovered to be an Inflammatory Disease

Researchers at the University of California, San Diego School of Medicine and Sun Yat-sen University in China have shown that acute glaucoma in mice is largely an inflammatory disease and that high pressure in the eye causes vision loss by setting in motion an inflammatory response similar to that evoked by bacterial infections.

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New Compound Treats Both Blindness and Diabetes in Animal Studies

In a new study led by UC San Francisco (UCSF) scientists, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes.

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An Alternative to Surgery for Graves’ Eye Disease

A low-carb, gluten-free diet with plenty of vegetables is helping a patient with Graves' eye disease to see normally again.

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Rehabilitation Helps Prevent Depression From Age-Related Vision Loss

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Depression is a common risk for people who have lost their vision from age-related macular degeneration (AMD), but a new study shows that a type of rehabilitation therapy can cut this risk in half.

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Depression in Age-Related Macular Degeneration Patients with Low Vision Can be Halved by Integrated Therapies

The first clinical trial to examine integrated low vision and mental health treatment has shown that the approach can reduce the incidence of depression by half among people with low vision due to age-related macular degeneration (AMD). The results of the study were published online today in Ophthalmology, the journal of the American Academy of Ophthalmology.

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NIH Study Reveals Gene Critical to the Early Development of Cilia

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Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia – sensory hair-like extensions present on almost every cell of the body. They show in a mouse model that without the gene Cc2d2a, cilia throughout the body failed to grow, and the mice died during the embryonic stage. The finding adds to an expanding body of knowledge about ciliopathies, a class of genetic disorders that result from defects in the structure or function of cilia.

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Soothing Cells, Peaceful Protein Could Hold Promise for Treating Autoimmune Uveitis

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Uveitis occurs when immune cells invade the eye, causing inflammation, swelling and vision loss. Researchers at the National Eye Institute (NEI) have found a unique type of immune cell and a secreted protein that, in tests on mice, can protect against the disease.

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