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Rotavirus Vaccine Given to Newborns in Africa is Effective

Mayo Clinic and other researchers have shown that a vaccine given to newborns is at least 60 percent effective against rotavirus in Ghana. Rotavirus causes fever, vomiting and diarrhea, which in infants can cause severe dehydration. In developed nations, the condition often results in an emergency room visit or an occasional hospitalization, but is rarely fatal. In developing countries, however, rotavirus-related illness causes approximately 500,000 deaths per year. The findings appear this week in the Journal of Infectious Diseases.

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Whooping Cough Can Be Deadly for Infants, but 61 Percent of Adults Don’t Know Vaccine Status

A new University of Michigan poll shows that 61 percent of adults say they don’t know when they were last vaccinated against pertussis, which could mean they might be unwittingly exposing vulnerable babies to the disease.

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The Upcoming Flu Season: What You Need to Know Now

New vaccine and regulations to impact patient care, prompt early vaccination.

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Experimental Vaccine Shows Promise Against TB Meningitis

A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.

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Workers Do Not Quit Due To Mandatory Flu Shot

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In its fourth year with 99 percent compliance, Loyola University Health System's mandatory flu shot program is the subject of a study presented by Jorge Parada, MD, Loyola University Health System, presented at an infectious disease conference.

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Vaccinating Children Against HPV?

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The Human papillomavirus, or HPV, and its link to certain cancers has been in the headlines recently, reigniting the debate whether it is appropriate to vaccinate children against the virus. Robert Haddad, MD, the disease center lead at Dana-Farber's head and neck oncology program offers comment.

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Gut Bacteria Play Key Role in Vaccination

The bacteria that live in the human gut may play an important role in immune response to vaccines and infection by wild-type enteric organisms, according to two recent studies from researchers at the University of Maryland School of Medicine

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Researchers Reveal Malaria's Deadly Grip

Discovery of how parasite sticks to blood vessels could lead to new means to combat malaria.

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Gene Therapy Gives Mice Broad Protection to Pandemic Flu Strains, Including 1918 Flu

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Researchers have developed a new gene therapy to thwart a potential influenza pandemic. They demonstrated that a single dose of an adeno-associated virus expressing a broadly neutralizing flu antibody into the noses of animal models gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus. These were isolated from samples associated from historic human pandemics – the infamous 1918 flu pandemic and another from 2009.

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Poliovirus Vaccine Trial Shows Early Promise for Recurrent Glioblastoma

An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.

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