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A reporter's PressPass is required to access this story until the embargo expires on 2-Apr-2015 2:00 PM EDT

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Oral Hepatitis B Vaccine Could Become a Reality

In a new study, researchers report progress toward perfecting a radical new method of producing vaccines using genetically modified corn. The approach could lead to an oral hepatitis B vaccine that requires no refrigeration and costs less than $1 per dose to manufacture.

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Ebola Whole Virus Vaccine Shown Effective, Safe in Primates

An Ebola whole virus vaccine, constructed using a novel experimental platform, has been shown to effectively protect monkeys exposed to the often fatal virus. The vaccine, described today (March 26, 2015) in the journal Science, was developed by a group led by Yoshihiro Kawaoka, a University of Wisconsin-Madison expert on avian influenza, Ebola and other viruses of medical importance.

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Enhanced Flu Protection: Four Beats Three

Findings by a Saint Louis University researcher parallel earlier results: Adding a strain of influenza B could improve effectiveness of an influenza vaccine.

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Finding Strengths — and Weaknesses — in Hepatitis C’s Armor

Using a specially selected library of different hepatitis C viruses, a team of researchers led by Johns Hopkins scientists has identified tiny differences in the pathogens’ outer shell proteins that underpin their resistance to antibodies. The findings, reported in the January 2015 issue of the Journal of Clinical Investigation, suggest a reason why some patients’ immune systems can’t fend off hepatitis C infections, and they reveal distinct challenges for those trying to craft a successful vaccine to prevent them.

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Radical Vaccine Design Effective Against Herpes Viruses

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The new vaccine was found to be effective against the two most common forms of herpes that cause cold sores (HSV-1) and genital ulcers (HSV-2). Both are known to infect the body’s nerve cells, where the virus can lay dormant for years before symptoms reappear. The new vaccine is the first to prevent this type of latent infection.

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Experimental Herpes Vaccine Upends Traditional Approach and Shows Promise

Scientists at Albert Einstein College of Medicine have designed a new type of vaccine that could be the first-ever for preventing genital herpes—one of the most common sexually transmitted diseases, affecting 500 million people worldwide. Using a counterintuitive approach, researchers were able to prevent both infections caused by herpes simplex virus type 2, which causes genital herpes. Findings from the research, conducted in mice, were published today in the online journal eLife.

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Human Antibodies Target Marburg, Ebola Viruses; One Step Closer to Vaccine

Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola.

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The Psychology Behind Why Parents Don't Vaccinate

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Polio Vaccination with Microneedle Patches Receives Funding for Patch Development, Clinical Trial

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The Georgia Institute of Technology and Micron Biomedical have been awarded $2.5 million in grants from the Bill & Melinda Gates Foundation to advance the development of dissolvable microneedle patches for polio immunization.