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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 30-Jun-2016 12:00 AM EDT

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Stopping Zika: Saint Louis University to Launch Human Vaccine Trial

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Saint Louis University's vaccine center has been tapped by the National Institutes of Health to conduct a human clinical trial of a vaccine to prevent the Zika virus, which can cause devastating birth defects in babies.

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Novel Study in Nairobi Infants May Accelerate Path to HIV Vaccine

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The first and only study to look at isolate HIV-neutralizing antibodies from infants has found that novel antibodies that could protect against many variants of HIV can be produced relatively quickly after infection compared to adults.

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The Wistar Institute Contributes Technology Critical to the Development of the First Zika Vaccine to Be Tested in Human Clinical Trial

The U.S. Food and Drug Administration has approved initiation of the first phase I human trial for a Zika vaccine, based on new research with key findings generated in the lab of David B. Weiner, Ph.D., executive vice president, director of the Vaccine Center, and the W.W. Smith Endowed Chair in Cancer Research at The Wistar Institute.

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Drones Could Be Cheaper Alternative to Delivering Vaccines in Developing World

Using unmanned drones to deliver vaccines in low- and middle-income countries may save money and improve vaccination rates, new research led by the Johns Hopkins Bloomberg School of Public Health and the Pittsburgh Supercomputing Center suggests.

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Top HIV Scientists Awarded $42 Million in National Institutes of Health Funding to Improve Efficacy of HIV Vaccine Platforms

With $42 million in funding from the National Institutes of Health, scientists from Beth Israel Deaconess Medical Center (BIDMC) and Oregon Health & Science University (OHSU) will lead a five-year research initiative to advance efforts to cure and prevent HIV/AIDS. Dan Barouch, MD, PhD, Director of the Center for Virology and Vaccine Research at BIDMC, and Louis Picker, MD, Assistant Director of the OHSU Vaccine and Gene Therapy Institute, will lead a consortium of researchers from across the country exploring the mechanisms behind promising new HIV vaccine candidates and potential cure strategies.

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Radiation and Vaccination Can Magnify Effects of Immunotherapy

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago – working with mice – were able to increase the response rate for these new immunotherapy agents. This sequence of treatments could open up unresponsive tumors to immune cell infiltration, boosting immunologic control of tumor growth.

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FDA Approves Vaccine for Cholera

In a milestone years in the making, a vaccine to prevent cholera was approved today by the U.S. Food and Drug Administration (FDA). The vaccine, Vaxchora, is the only approved vaccine in the U.S. for protection against cholera. Its licensure allows for use in people traveling to regions in which cholera is common, including travelers, humanitarian aid workers, and the military.

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Antibodies Triggered by Avian Influenza Virus Vaccine Illuminate a New Path Toward a Universal Flu Vaccine

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today’s vaccines typically provide, according to a study

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Mobile Laboratories Help Track Zika Spread Across Brazil

Researchers from the University of Birmingham are working with health partners in Brazil to combat the spread of Zika virus by deploying a pair of mobile DNA sequencing laboratories on a medical ‘road trip’ through the worst-hit areas of the country.

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Pneumococcal Vaccine Watches Bacteria, Strikes Only When Needed

Conventional vaccines indiscriminately destroy bacteria and other disease-causing agents. The approach works, but there is growing concern that it creates opportunity other pathogens to harm the body – similar to antibiotic resistance resulting in new and more potent pathogens. A new, protein-based pneumococcal vaccine takes a different approach. It allows pneumonia-causing bacteria to colonize in the body and – like a nightclub bouncer – swings into action only if the bacteria becomes harmful.

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Recent Research Uncovers Surprises About Antibiotic Resistance

It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones.

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Reported Data on Vaccines May Not Build Public Trust or Adherence

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Recently, University of Missouri researchers proposed that open communication about the Vaccine Adverse Event Reporting System (VAERS) could improve public trust that vaccines are safe, thereby increasing vaccine acceptance. Findings from the study suggest that data and stories may not increase the public’s acceptance of vaccines.

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Penn Study Describes a Better Animal Model to Improve HIV Vaccine Development

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Vaccines are usually medicine’s best defense against the world’s deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists’ attempts to make an effective vaccine to protect against it. Now, researchers have figured out how to make a much-improved research tool that they hope will open the door to new and better HIV vaccine designs.

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Swine Researcher to Share Expertise on Colibacillosis

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“It’s the diarrhea that can kill you,” noted professor emeritus David Francis, an expert on colibacillosis, an intestinal disease that affects newborn and weanling pigs. The toxin-producing E. Coli bacterium that causes the swine disease is similar to the organism responsible for traveler’s diarrhea in humans. Francis will speak at the 24th International Veterinary Conference in Dublin, Ireland, June 7-10.

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New Study Finds That in Resource-Poor Settings, Vaccinating Mothers Against Flu Can Protect Newborns Too

Each year, influenza causes between 250,000 and half a million deaths around the world. Now a new study has shown that immunizing mothers against flu can decrease by 70 percent the risk of their infants getting flu during the first four months after birth. This is the largest study so far to show that maternal vaccination against flu is feasible and effective in resource-poor environments.

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Immunotherapy Developed at Roswell Park Being Tested as Treatment for Multiple Myeloma

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An early-stage clinical trial at Roswell Park will assess whether the SurVaxM cancer vaccine is a safe and effective treatment option for patients with multiple myeloma, in combination with lenalidomide

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Google Searches for 'Chickenpox' Reveal Big Impact of Vaccinations

Countries that implement government-mandated vaccinations for chickenpox see a sharp drop in the number of Google searches for the common childhood disease afterward, demonstrating that immunization significantly reduces seasonal outbreaks.

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Spring Snow a No-Go?

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Spring snowpack, relied on by ski resorts and water managers throughout the Western United States, may be more vulnerable to a warming climate in coming decades, according to a new University of Utah study.

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There's (Now) an App for That

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Known as a definitive source for health care providers, "The Vaccine Handbook" is now available as an app.