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Research Finding Could Lead to New Therapies for Patients with Gluten Intolerance

Elafin, by interacting with the transglutaminase 2 enzyme, decreased the enzymatic reaction that increases the toxicity of peptides derived from gluten.

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Mayo Clinic Researchers Find Genetic Clue to Irritable Bowel Syndrome

Is irritable bowel syndrome (IBS) caused by genetics, diet, past trauma, anxiety? All are thought to play a role, but now, for the first time, researchers have reported a defined genetic defect that causes a subset of IBS. The research was published in the journal Gastroenterology.

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Not Just the Gut: Negative Relationships, Fatigue Are More Powerful Than Symptoms in Ibs Patients’ Health Perceptions

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Social relationships, fatigue and other coexisting medical problems have a stronger effect on how patients with irritable bowel syndrome (IBS) rate their overall health than the severity of their gastrointestinal symptoms, a University at Buffalo study has found.

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Deficient Protein GM-CSF Production Found to Impair Gut’s Immune Tolerance

This research revealed that inflammation in the gut GM-CSF is produced in the normal gut in response to microbiota signals by specialized cells, requires sufficient GM-CSF to protect against gut inflammation. Deletion of GM-CSF gene in the mouse impaired gut regulatory function and compromised oral tolerance, and increased susceptibility to IBD.

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Getting the Gut to Grow: Nutrition Experts Help Children with Short Bowel Syndrome

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Parents of children with short bowel syndrome measure their outcomes by the centimeters of intestine that remain after surgery. Many of these children live on intravenous nutrients and fluids, in combination with formula by a gastric tube in and a strict diet. All face daily challenges—infections, diarrhea and liver disease. Through a collaborative project with clinical researchers and a microbiologist in Canada, assistant professor Crystal Levesque of the South Dakota State University Animal Science Department hopes to help in finding a treatment that will help grow their intestines. Beginning its second year, the project has been supported by an annual $25,000 Maurice Shils Grant from the Nestlé Nutrition Institute awarded through the American Society for Parenteral and Enteral Nutrition Rhoads Research Foundation.

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Implantable ‘Bracelet’ Brings Relief to GERD Sufferers

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An innovative laparoscopic procedure that implants a ring of magnetic beads to help prevent acid reflux in patients who suffer from Gastroesophageal Reflux Disease (GERD) is the latest tool surgeons at Stony Brook University Hospital (SBUH) have to treat the disease.

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McMaster Researchers Discover Secret of Bowel Movement

The McMaster team found that segmentation motion occurs when not one but two sets of pacemakers interact with each other to create a specific rhythm. Then they work together with nerves and muscle to generate the movement that allows for nutrient absorption.The discovery is important as it gives direction for development of drugs or nutrients which will combat disorders when people have diarrhea, constipation, bloating or malabsorption of nutrients from food.

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Quinoa Well Tolerated in Patients with Celiac Disease

Adding quinoa to the gluten-free diet of patients with celiac disease is well-tolerated, and does not exacerbate the condition, according to new research published in The American Journal of Gastroenterology.

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Chronic Intestinal Damage Raises Hip-Fracture Rate in Celiac Disease Patients

Celiac disease patients who experience chronic damage in the small intestine may be more likely to break a hip than those whose intestinal tissues have begun healing, according to new research accepted for publication in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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New, “Designer” Fiber May Help Address Fiber Intolerance and Ease IBS Symptoms

A newly-developed, “designer” dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for Irritable Bowel Syndrome (IBS) which affects 10-20 percent of the population, disproportionately women.

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