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Four Genes Identified That Influence Levels of 'Bad' Cholesterol

Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of “bad” cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease.

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Spontaneous Mutations Play a Key Role in Congenital Heart Disease

Although genetic factors contribute to congenital heart disease, many children born with heart defects have healthy parents and siblings, suggesting that new mutations that arise spontaneously—known as de novo mutations—might contribute to the disease. New research shows that about 10 percent of these defects are caused by genetic mutations that are absent in the parents of affected children.

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Review on Aspirin to Treat and Prevent Heart Attacks and Commentary on Aspirin to Prevent Colorectal and Other Cancers

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A commentary and review provides clinicians with the optimal utilization of aspirin to treat and prevent heart attacks, and advice on aspirin in the prevention of colorectal and other cancers.

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Type 1 Diabetes and Heart Disease Linked by Inflammatory Protein

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque.

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New Study Confirms Link between Weight Loss and Blood Pressure for Individuals with Specific Genetic Polymorphisms

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Your genetic makeup can help determine how well your body will respond to weight loss efforts aimed at controlling high blood pressure, a new study confirms. The multi-institutional study, led by researchers at The Cardiovascular Institute, part of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, may help clarify how hypertension develops and progresses in certain individuals and also identify people for whom weight loss programs are most likely to help reduce blood pressure.

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Study Identifies New Gene Variations Associated With Heart Rate

Findings pinpoint 14 genetic targets in humans that may provide insight for the treatment of cardiovascular disease.

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Tablet Computers Acceptable for Reading EEG Results, Mayo Clinic Study Says

Mayo Clinic physicians in Arizona have shown that tablet computers can be used to analyze electroencephalogram or EEG results outside of the clinic or hospital. Their study findings were recently presented at the American Academy of Neurology conference in San Diego.

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Commonly Used Cholesterol Calculation Underestimates The Heart Disease Danger For Many

In what promises to be an eye-opener for many doctors and patients who routinely depend on cholesterol testing, a study led by researchers at the Johns Hopkins University School of Medicine found that the standard formula used for decades to calculate low-density lipoprotein (LDL) cholesterol levels is often inaccurate. Of most concern, the researchers say, is their finding that the widely used formula underestimates LDL where accuracy matters most — in the range considered desirable for high-risk patients. Results of the study are published in an online article, ahead of print, in the Journal of the American College of Cardiology.

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Can We Treat a “New” Coronary Heart Disease Risk Factor?

Depressive symptoms after heart disease are associated with a markedly increased risk of death or another heart attack. However, less has been known about whether treating heart attack survivors for depressive symptoms could relieve these symptoms, be cost-effective, and ultimately, reduce medical risk? Columbia University Medical Center’s Karina W. Davidson, PhD and her research team now report a patient-centered approach that answers these questions in the affirmative.

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Pneumonia Patients Nearly Twice as Likely to Suffer From Depression, Mental and Physical Impairments

Long-term cognitive and functional impairments that follow pneumonia hospitalization are comparable to the negative health effects of heart disease.

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