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Study Links Better “Good Cholesterol” Function With Lower Risk of Later Heart Disease

HDL, the “good cholesterol” helps remove fat from artery walls, reversing the process that leads to heart disease. Yet recent drug trials and genetic studies suggest that pushing HDL levels higher doesn’t reduce the risk of heart disease. Now, an epidemiological study shows that a person’s HDL function—the efficiency of HDL molecules at removing cholesterol—may be a better measure of coronary heart disease risk and target for heart-protecting drugs.

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Trending Stories Report for 21 May 2015

Trending news releases with the most views in a single day. Topics include: gun regulation, psychology and altruism, big data, threats to coral reefs, extra-terrestrial life, personalized diets, metabolic syndrome and heart health, new drug target to treat arthritis, and archeologists find oldest tools.

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Heart Disease No. 1 Killer of Women in the U.S.

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Early Detection and Treatment of Type 2 Diabetes May Reduce Heart Disease and Mortality

Screening to identify Type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research that combined large scale clinical observations and innovative computer modelling.

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Trending Stories Report for 18 May 2015

Trending news releases with the most views in a single day. Topics include: nutrition, fibromyalgia, e-cigarettes, cystic fibrosis, asthma, and gluten

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Metaphors of the Heart: Two Physicians Examine Heart Disease Through a Literary Lens

Heart disease has topped mortality charts as the No. 1 killer of men and women for many decades, but a novel analysis of American literary fiction by two physicians finds the disorder’s presence in great novels has remained relatively modest.

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Using Fresh Whole Blood Lowers Childrens' Donor Exposure Risk in Heart Surgery

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Children who undergo heart surgery are better off receiving fresh whole blood transfusions from a single donor, rather than receiving component blood from multiple donors. Limiting donor exposures reduces the patients' risk of complications.

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DCRI Leads PCORnet Study On Aspirin Dose for Heart Disease Patients

The Duke Clinical Research Institute is launching an ambitious new project that is intended to answer a question of considerable clinical importance, while also changing the way pragmatic clinical trials are conducted. The Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) study will assess whether low- or standard-dose aspirin is better for preventing heart attacks and stroke in patients with coronary artery disease.

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Frailty Among Older Heart Patients Helps Predicts Severe Outcomes

Frailty among older people with cardiovascular disease appears to be more predictive than age for gauging their risk of heart attack, stroke and death, according to an international study that included researchers at Duke Medicine.

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Genome Library, Blood Test Aim to Minimize Statin Side Effects, Maximize Benefits

In the midst of the growing and often conflicting data around the benefits of statins, researchers are developing gene-based resources to help improve statin efficacy and cost-effectiveness and to reduce the incidence of adverse effects – some of which can be fatal.