Requiring physicians to report patients with dementia to state driver’s licensing authorities is not associated with fewer hospitalizations from motor vehicle crashes. However, in-person license renewal laws and vision testing dramatically cut crashes involving drivers with dementia.
Stable, biocompatible microcapsules have gained a new power — the ability to scavenge reactive oxygen species. This may aid microcapsule survival in the body as the tiny polymer capsules carry a drug or other biomolecules, or find use in antioxidant therapy or industrial applications.
Amyloid plaques have long been believed to be an indicator of neurodegenerative disease. But according to Raymond Anderson, a graduate student in West Virginia University's School of Medicine, such buildup alone does not correlate with disease severity. In fact, these buildups may even protect neurons.
People with Alzheimer’s disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers at Washington University School of Medicine in St. Louis have found that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer’s.
A paper published today in the New England Journal of Medicine reports that solanezumab, a monoclonal antibody-based treatment for Alzheimer’s disease developed by Eli Lilly that targets amyloid plaques, did not significantly slow cognitive decline.
New help may be on the way for people with dementia with Lewy bodies, which is the second most common neurodegenerative type of dementia after Alzheimer’s disease. The disease can cause movement problems and issues such as hallucinations in addition to thinking and memory problems. But the drug used to treat the movement problems can also exacerbate the hallucinations, delusions and other psychiatric problems.
New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease, Parkinson’s disease, and mental health disorders that affect cognitive abilities.
Lab-grown human neurons will help researchers develop and test treatments for devastating diseases, including Alzheimer’s disease, Parkinson’s disease and Amyotrophic lateral sclerosis.
Take twice daily, curcumin - found in turmeric - boosted memory by 28 percent in double-blind, placebo-controlled study
New findings could change how iron metabolism in the human body is understood, and open new horizons for research and therapeutics for inflammatory diseases and neurodegenerative diseases, such as Alzheimer’s and Parkinson's disease.
Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer’s disease. The award enables the researchers to develop computer algorithms that search existing drug databases, and to test the most promising drug candidates using patient electronic health records and Alzheimer’s disease mouse models.
Sleeping less than the recommended eight hours a night is associated with intrusive, repetitive thoughts like those seen in anxiety or depression, according to new research from Binghamton University, State University of New York.
对于轻度认知障碍（mild cognitive impairment）的患者，如果医生所开的药方是锻炼而不是药物治疗，请不要感到惊讶。 新的指导方针建议该病患者每周锻炼两次以改善记忆和思维。 该建议是在美国神经病学会医学杂志“神经病学”（Neurology）上发表的更新的轻度认知障碍指南的一部分。
Scientists from four different institutions are working together to identify a biomarker for Alzheimer's Disease using mice that travel an 850-mile circuit to test the efficacy of special technology called Quest MRI.
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