The number of low-income patients screened for colorectal cancer more than tripled after Medicaid expansion in 2014, according to study findings in the Journal of the American College of Surgeons.
Biologic age, a DNA-based estimate of a person’s age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. If a woman’s biologic age was older than her chronologic age, she had a 15 percent increased risk of developing breast cancer.
Research published in the American Journal of Public Health shows CommunityRx helps patients gain confidence finding health resources in their own neighborhoods.
A pair of Affordable Care Act clauses had a sizable effect on the ability of people with diabetes to get health insurance, a new study suggests. Before the requirements took effect, the percentage of people with private health insurance who had diabetes had declined, but it began to increase again after the ACA required insurers to accept people with pre-existing conditions, and limited their ability to charge higher rates to older people.
Bioengineers are designing aortic heart valve replacements made of polymers rather than animal tissues. The goal is to optimize valve performance and enable increased use of a minimally-invasive method for valve replacement over the current practice of open heart surgery.
A new method of increasing the reactivity of ultrathin nanosheets, just a few atoms thick, can someday make fuel cells for hydrogen cars cheaper, finds a new Johns Hopkins study.
Scientists at Scripps Research, inspired by electric car batteries, have developed a battery-like system that allows them to make potential advancements for the manufacturing of medicines.
Over-testing for urinary tract infections (UTIs) leads to unnecessary antibiotic use, which spreads antibiotic resistance. Infectious disease specialists at Washington University School of Medicine in St. Louis made changes to hospital procedures that cut urine tests by nearly half without compromising doctors’ abilities to detect UTIs.
When a honey bee turns 21 days old, she leaves the nest to look for pollen and nectar. For her, this is a moment of great risk, and great reward. It’s also the moment at which she becomes recognizable to other bees.
A multi-institutional, international team of researchers has developed a method that identifies individuals recently infected with Vibrio cholerae O1. The results of the study are available online in the February 20 issue of the journal Science Translational Medicine.
Through a recent five-year, $2.3 million grant from the National Institutes of Health (NIH), University of Kentucky faculty Don Frazier and Brett Spear will partner with faculty from qualified minority-serving institutions across the U.S. and Puerto Rico to help improve diversity in science and health care.
Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair.
Patients were found to often be willing to share their Google search histories with medical researchers, revealing that many do searches on their health concerns long before deciding to go to the hospital.
Needle biopsies detect rejection after a transplanted organ is already in trouble and sometimes miss the mark. And the needle damages tissue. This biocompatible nanoparticle goes to work at the first sign of trouble and could give clinicians much more information with a simple urine test.
In the quest to design more efficient solar cells and light-emitting diodes (LEDs), a team of engineers has analyzed different types of defects in the semiconductor material that enables such devices to determine if and how they affect performance.
Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system’s ability to fight melanoma in mice. The agents, dubbed s-DAB-IL-2 and s-DAB-IL-2(V6A), comprise a regulatory protein called human interleukin-2 fused to chemically modified portions of diphtheria toxin.
Patients taking diuretics are often at risk for low potassium levels, which can put patients at an increased risk of death from cardiac arrhythmias or other causes. But researchers from the Perelman School of Medicine at the University of Pennsylvania found that taking prescription potassium supplements can reduce these patients’ risk by nearly 10 percent as daily outdoor temperatures increase—a time when patients may be at highest risk due to loss of potassium while sweating. These findings are detailed in a study published today in BMJ Open.
A new animal study describes how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life. Investigating the fetal signaling pathways active in this biological event may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.
A new map of newborn babies’ brains offers details of structure that will provide a new reference for researchers studying both typical brain development and neurological disorders. Using noninvasive, 20-minute MRI scans, researchers have revealed some of the complex and precisely organized brain architecture that emerges as the brain reshapes itself during the third trimester of pregnancy.
Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. Investigating the fetal signaling pathways active in the biological events by which alveoli form may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.
Artificial Intelligence is helping to guide and support some 50 breast cancer patients in rural Georgia through a novel mobile application that gives them personalized recommendations on everything from side effects to insurance.
Keck School of Medicine of USC scientists have developed the first standardized framework for clinicians to document physical findings on older patients for better evidence in abuse cases
Project CLEAR clinical trial finds that the application of antiseptic soap, mouthwash, and nose ointments prevent post-discharge MRSA infections and hospitalizations. Patients
Researchers from the University of Michigan Rogel Cancer Center have found that a genetic mutation seen in about half of all brain tumors produces a response that prevents radiation treatment from working. Altering that response using FDA-approved drugs restores tumors’ sensitivity to radiation therapy, extending survival in mice.
A high proportion of multidrug-resistant tuberculosis (TB) cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of Congo.
A new tool from the Keck School of Medicine of USC can improve development and effectiveness of leading-edge cancer therapies derived from patients’ immune systems.
By examining how mammary cells respond in a stiffness-changing hydrogel, researchers discovered that several pathways work together to signal breast cells to turn cancerous. The work could inspire new approaches to treating patients and inhibiting tumor growth.
Once deemed nothing more than signal-transmitters, the axons of nerve cells now emerge as far more complex and autonomous than thought, according to new research
When normal cells grow, divide or do any job in the body, they do so in response to a whole slew of internal sensors that measure nutrients and energy supply, and environmental cues that inform what happens outside the cell.
Research has shown patients are discussing initial cancer treatment options with their primary care doctors. And now a new study finds that a significant number of these physicians report notable gaps in their knowledge of cancer treatment options.
Researchers at University of Utah Health detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.
University of Minnesota medical researchers and engineers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3D in vitro model (i.e. in a culture dish rather than in a human or animal).
Researchers at the University of Pittsburgh School of Medicine have identified a brain protein at the root of how the brain recovers from stroke. The finding offers a promising avenue for developing therapies that could work even when given beyond the first few hours after a stroke.
A detailed analysis of blood samples from Ebola patients is providing clues about the progression of the effects of the virus in patients and potential treatment pathways. The findings point to a critical role for a molecular pathway that relies on the common nutrient choline, as well as the importance of cellular bodies known as microvesicles.
Using super-sensitive microscopic imaging, a team of scientists made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish through narrow openings without springing a leak.
Director of the Southwest National Primate Research Center Professor Deepak Kaushal, Ph.D. says research he collaborated on is pinpointing a possible new avenue of protection for HIV/AIDS patients. The study, published this month in the journal Cell Reports helps scientists better understand how HIV promotes deadly cases of tuberculosis (TB).
A new Johns Hopkins study found that rats’ ability to recalibrate learned relationships among time, speed and distance is ever-evolving, moment-by-moment.
A drop of rainwater that falls on a cassava field in Uganda takes a different path than one that falls 500 miles east in Somalia. Knowing where rain comes from now, and where it might come from under future climate scenarios, is important for the millions of people who rely on subsistence agriculture to survive. Research from Washington University in St Louis offers a new tool for tracking the rainwater race.
UC San Diego’s Alison Coil and colleagues James Aird (University of Leicester, UK) and Antonis Georgakakis (National Observatory of Athens) recently published research findings to reveal how supermassive black holes are growing at the center of galaxies, and how that growth relates to the growth of galaxies themselves.
Results from a large, multi-center study suggest that cardiac magnetic resonance, or CMR, has potential as a non-invasive, non-toxic alternative to stress echocardiograms, catheterizations and stress nuclear exams in identifying the severity of coronary artery disease.
Researchers at Beth Israel Deaconess Medical Center found that higher sodium intake, when studied in the context of the DASH-Sodium trial (Dietary Approaches to Stop Hypertension), increases lightheadedness. These findings challenge traditional recommendations to increase sodium intake to prevent lightheadedness.
Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock could control human aging and may underlie blood cancers.
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.
Researchers at the University of Michigan Rogel Cancer Center have cataloged circular RNA in multiple cancers and conducted initial research that suggests these stable structures could serve as cancer biomarkers in blood or urine.
In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression. A compound developed by the Johns Hopkins Drug Discovery Group targets a chemical in specific cells of the mammalian brain, and eases signs of social avoidance and depression in rodents, without some of the toxic side effects that have bedeviled its parent compound.
New findings published in “Nature Communications” could apply to the manufacture of self-assembling nanomaterials and the creation of environmentally responsive sensors. This could lead to new methods for making nanoscale devices and more economical medical, point-of-care diagnostics.
Each year, some 600 million people around the world come down with strep throat. Yet, it was unclear why some kids are prone to repeated bouts of strep throat while others appear to be more or less immune. The latest study by researchers at La Jolla Institute for Immunology (LJI) provides the first clues why some children are more susceptible than others to contracting recurrent strep throat.
New computer machine learning techniques can be now be used in crowdsourcing projects to deal with massively increasing amounts of data—making computers a surprising new partner in citizen science projects.
Treatment with the NSAID carprofen triggers subtle low-grade inflammation in the heart and kidneys. The combination of carprofen pretreatment and heart attack magnifies this impact by dysregulating the acute inflammatory response, amplifying inflammation and intensifying the cardiorenal syndrome.
Building a circle of trusted adults around a suicidal teen, to support them during vulnerable times, may have long-term effects that reduce their risk of dying young, a new study suggests. About 12 years after the teens were hospitalized for suicidal behaviors, far more of the young people who got standard care had died, compared with young adults in the group that had received the extra adult support.
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