Feature Channels: Biotech

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Together with colleagues from the Institute of Biomedical Chemistry, biologists from the Research Center of Biotechnology RAS have studied a new L-asparaginase from hyperthermophilic archaea Thermococcus sibiricus. These archaea live at a depth of more than two thousand meters in a high-temperature oil reservoir in Siberia. This biotechnologically important enzyme is used in the food industry, in the development of biosensors, and in medicine due to its antitumor activity. L-asparaginase from T. sibiricus was described for the first time by the authors of this research. This enzyme differs from the previously described analogs by its increased stability and selective toxicity to cancer cells.

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Biofabrication company to advance key tissue applications

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Research led by the University of Alabama in Huntsville (UAH) has for the first time identified the precise genetic operational structure of a key system in Escherichia coli (E. coli) bacteria, opening the door to possible new antibiotics to treat the infections it causes.

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In Applied Physics Reviews, researchers review scientific advances of electrolyte-gated carbon nanotube field-effect transistor biosensors, which are characterized by superior electronic properties and intrinsic signal amplification and are capable of detecting a wide range of biomolecules with high sensitivity. One of their main components is the biorecognition element, which selectively recognizes the analyte of interest. Biotransduction devices convert the interaction between the biorecognition element and analyte into a measurable signal.

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Hertz Fellows Judy Savitskaya, Katie Bodner Spielberg, and Kelly Moynihan transitioned to biotech venture capital after receiving their PhDs in bioengineering, enabling them to work closely with forward-thinking entrepreneurs and promising new biotechnologies.

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Alloplex Biotherapeutics and Hackensack Meridian Health announce Equity Investment

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Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy’s Oak Ridge National Laboratory.

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In APL Bioengineering, researchers have developed an approach to print skin equivalents, which may play a future role in facilitating the healing of chronic wounds. They used suspended layer additive manufacturing, creating a gel-like material to support the skin equivalent that can then support a second phase of gel injection. During printing, the skin layers are deposited within the support gel. After printing, the team washed away the support material, leaving behind the layered skin equivalent.

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Just as convincing images of cats can be created using artificial intelligence, new proteins can now be made using similar tools.

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Researchers have made significant advances toward the goal of a new microchip able to grow DNA strands that could provide high-density 3D archival data storage at ultra-low cost – and be able to hold that information for hundreds of years.

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A novel medical device that works as an absorbable implant for meniscal reconstruction, invented by researchers at Rutgers, The State University of New Jersey, received the 2021 Thomas Edison Patent Award in the Biotechnology category. The tissue-engineered implant treats meniscal tears to lessen or even entirely rid the need for a total knee replacement surgery. The implant also recreates the anatomy and fiber geometry of the meniscus.

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In research published in Langmuir, a team led by Steven Cramer, an endowed chair professor of chemical and biological engineering at Rensselaer Polytechnic Institute, explored the fundamentals of how different molecules interact with various surfaces during the purification process.

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According to the latest Association of University Technology Managers (AUTM) North American Annual Licensing Survey, the University Health Network (UHN) ranks as the #1 research commercialization institution in Canada for the second year running according to gross licensing revenue from the research it has commercialized.

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New Berkeley Lab breakthroughs: engineering chemical-producing microbes; watching enzyme reactions in real time; capturing the first image of ‘electron ice’; revealing how skyrmions really move

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With the signing of a statement of cooperation, the BioProducts Institute at the University of British Columbia (BPI) and Empa are celebrating a new partnership to promote innovation and collaboration, furthering joint developments in the field of biobased solutions.