Feature Channels: Genetics

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Mount Sinai study could lead to new treatments for fibromuscular dysplasia

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The “Ozempic Revolution” did not start with celebrities posting their weight-loss success stories on Instagram, or slick TV ads featuring the earworm jingle: “Oh, Oh, Oh, Ozempic!”

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A new USDA-supported project based at Iowa State University will create an encyclopedia of livestock species' genetic regulatory regions, a DNA netherworld that could be useful in breeding for improved animal efficiency and health.

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A study by UdeM professor Claude Perreault's team at IRIC proposes three potential functions for so-called parasite DNA sequences in T cell development.

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A pivotal study has revealed the genetic drivers of red pigmentation in apple flesh, highlighting the critical role of anthocyanins and flavan-3-ols. By mapping quantitative trait loci (QTL) across diverse apple families, researchers identified key genetic regions linked to this vibrant coloration, setting the stage for developing apples with deeper hues and enhanced health benefits.

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A recent study has identified CaSLR1, a gene in pepper plants, as a key regulator of stem strength by controlling cell wall development. This discovery offers significant potential for agriculture, paving the way for breeding crops with enhanced resistance to lodging. Such improvements can lead to increased yield stability and reduced production costs, providing substantial benefits for farmers.

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Doctors can help prevent ovarian cancer, but historically the cost of preventative surgery has been menopause. A Penn State Health expert discusses why it’s worth it, and how medical technology is catching up with this insidious disease.

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A UCLA-led study involving mice and human data could also have implications for individuals with diabetes and obesity, uncovering new treatment possibilities for life-threatening arrhythmias.

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A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.

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A pivotal study has decoded the genetic basis of olive oil production, revealing a key regulatory mechanism that shapes oil biosynthesis. By mapping the olive tree’s genome and metabolic pathways, researchers have identified how MYC2, a critical transcription factor, orchestrates the balance between fatty acid and flavonoid synthesis.

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A recent study sheds light on Panax notoginseng, also known as Sanchi, by delving into its phytochemical profile and pharmacological potential. The research provides an in-depth review of the biosynthesis and regulation of ginsenosides, the herb's primary bioactive compounds known for their therapeutic effects.

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Scientists have decoded the genetic blueprint of Atractylodes lancea, a prized herb in traditional Chinese medicine. Through comprehensive genome resequencing, the study unveils how natural variations drive the plant's evolution and metabolic adaptations, particularly affecting the production of key medicinal compounds.

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Temple University’s Sbarro Institute for Cancer Research and Molecular Medicine has benefited from the support of Pennsylvania State Sen. Ryan Aument since he took office in 2014.

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A recent study discovered that applying 5-Azacytidine, a DNA methylation inhibitor, significantly reduces tomato susceptibility to gray mold, a common postharvest fungal disease. This epigenetic strategy enhances the fruit's natural defense system, offering a sustainable and innovative method to boost crop resistance without genetic modification.

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UNC School of Medicine researchers are the first to show that an microRNA molecule called miR-29 is instrumental in driving the natural aging process.

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Demand for cancer genetic testing is on the rise, but there's not enough genetic counselors to guide patients through the process. Researchers say chatbots could be the answer.

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Scientists have identified a crucial gene, CsMIKC1,that controls the number of flowering sites in Cannabis sativa, a finding that could significantly enhance both medicinal and grain yields. The study reveals how CsMIKC1 drives inflorescence development, offering new pathways to boost productivity in Cannabis cultivation.

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Cancer cells appear to hijack a genetic pathway involved in DNA repair to drive malignancy and overcome treatment, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Cell, explain how chromosomes in some tumors undergo massive rearrangements and could lead to new strategies to avoid cancer drug resistance.