Dental health and diet may have an impact on the development and severity of psoriasis, according to a study by dermatologists at The Ohio State University Wexner Medical Center. Psoriasis is a skin disease that causes thick, itchy patches of red skin with silvery scales and affects more than 8 million Americans.
In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.
Immunologists at St. Jude Children’s Research Hospital have discovered key biological switches that control regulatory T cells—specialized white blood cells that keep the immune system in check.
A new study, led by researchers at the University of Chicago, provides an answer to why cancer cells consume and use nutrients differently than their healthy counterparts and how that difference contributes to their survival and growth.
A study in humans and mice demonstrated that a fetus has its own microbiome, or communities of bacteria living in the gut, which are known to play important roles in the immune system and metabolism. Researchers also confirmed that the fetal microbiome is transmitted from the mother. These findings open the door to potential interventions during pregnancy to stimulate the fetal microbiome when a premature birth is expected, to help the baby grow faster and be better equipped to tolerate early life infection risk. The study was published in the journal JCI Insight.
The American Autoimmune Related Diseases Association (AARDA), a nonprofit education and advocacy organization dedicated to the eradication of autoimmune diseases, appointed Randall Rutta as President and CEO. Rutta succeeds founder and long-time President and Executive Director Virginia Ladd, who will now serve as Advisor to the President following a nearly 30-year run with the organization.
In a paper published in Annals of Neurology, a physician-scientist at Beth Israel Deaconess Medical Center (BIDMC), and colleagues report the presence of cellular features consistent with an immune response targeting specialized brain cells in more than two thirds of autistic brains analyzed postmortem. These cellular characteristics – not previously observed in autism – lend critical new insight into autism’s origins and could pave the way to improved diagnosis and treatment for people with this disorder.
The first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and understand if we are predisposed to autoimmune diseases before birth.
The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity. Scientists from the lab of Meinrad Busslinger now reported in the journal "Nature Immunology" how the protein lkaros orchestrates the fine balance between B cell silencing and activation - and thereby controls autoimmunity.
Below are summaries of recent Fred Hutch research findings, with links for additional background and media contacts.
A team of college interns at Sandia National Laboratories has built autonomous drones to try out new navigation, guidance and control, and target recognition techniques ultimately bound for autonomous hypersonic vehicles.
A study largely validates that immunoglobulin IgG is a crucial part of the pathogenic immunodeposits in kidneys of patients with IgA nephropathy. The routine clinical test that identifies the presence of IgA in all cases of IgA nephropathy fails to show IgG in 50 to 80 percent of biopsies.
Grammy® Nominated Songwriter and Singer Dayna Caddell to Lead 5th Annual Los Angeles Autoimmune Walk on November 3. Former NFL Dallas Cowboys Player Darryl Clack is the Featured Speaker. The Walk is part of AARDA's "Linking Together for a Cure" campaign to raise awareness and funding for research.
Named a major women’s health issue by the National Institutes of Health’s Office of Research on Women’s Health, it is no surprise that the number of celebrities impacted by autoimmune disease is on the rise. Kim Kardashian West recently opened up about the impact of autoimmune disease on her life. Other celebrities with autoimmune disease diagnoses include Venus Williams, Selena Gomez, and Missy Elliott.
The American Autoimmune Related Diseases Association (AARDA) partners with AHN Autoimmunity Institute to present a free public forum on autoimmune disease and the inaugural Pittsburgh Autoimmune Walk.
Researchers have found a synergistic connection, or crosstalk, between two rare but potentially deadly blood-clotting diseases — thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. The linkage may provide a rationale for a more targeted therapeutic intervention in patients.
A children’s book published by Hospital for Special Surgery for youngsters with lupus not only explains the illness, but offers a message of encouragement and hope. The book, written by a hospital volunteer with lupus, has received excellent reviews from health professionals around the country.
The American Neuromuscular Foundation has a new chronic inflammatory demyelinating polyneuropathy development grant award recipient, Dr. Karissa Gable.
AARDA presents a free health and wellness event focused on autoimmune patients and families
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