An epigenetic modification that occurs in a major cell type in the brain’s reward circuitry controls how stress early in life increases susceptibility to additional stress in adulthood, researchers at the Icahn School of Medicine at Mount Sinai have learned.
Value & Outcomes Spotlight, a bimonthly ISPOR news publication for the global health economics and outcomes research community, announced the publication of a special supplement exploring value assessment of new interventions in Alzheimer’s disease.
UC Davis Health researchers studying executive control in adolescents and young adults with autism have published new research that suggests a unique approach, rather than impairment.
Scientists at the Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins clump and spread between nerve cells in the brain.
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.
Results published today show it is possible to identify Parkinson's based on compounds found on the surface of skin.
These findings clearly demonstrate how the cooperative areas of the brain responsible for reading skill are also at work during apparently unrelated activities, such as multiplication, suggesting that reading, writing and arithmetic, the foundational skills informally identified as the three Rs, might actually overlap in ways not previously imagined, let alone experimentally validated.
A new study of Medicare payments has found that over a five-year period, the payments for medications prescribed to people with neurologic conditions like multiple sclerosis (MS), Parkinson’s disease and epilepsy increased by 50% while the number of claims for these prescription medications only rose by only 8%. The study is published in the March 10, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Eating a healthy, plant-based diet that includes foods like vegetables, whole grains and beans, and decreasing intakes of less healthy foods like refined grains or added sugars may reduce your risk of having a stroke by up to 10%, according to a study published in the March 10, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found a diet high in quality plant-based foods may reduce your risk of having an ischemic stroke.
A team of UNLV neuroscientists are uncovering how psychedelics affect brain activity. Their work, published recently in Nature: Scientific Reports, shows a strong connection in rodent models between brain activity and behaviors resulting from psychedelic treatment, a step forward in the quest to better understand their potential therapeutic effects.
UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer’s disease and other forms of dementia.
While neurological complications of COVID-19 in children are rare, in contrast to adults, an international expert review of positive neuroimaging findings in children with acute and post-infectious COVID-19 found that the most common abnormalities resembled immune-mediated patterns of disease involving the brain, spine, and nerves. Strokes, which are more commonly reported in adults with COVID-19, were much less frequently encountered in children. The study of 38 children, published in the journal Lancet, was the largest to date of central nervous system imaging manifestations of COVID-19 in children.
People over 65 shouldn’t take three or more medicines that act on their brain and nervous system, experts strongly warn, because the drugs can interact and raise the risk of everything from falls to overdoses to memory issues. But a new study finds that 1 in 7 people with dementia who live outside nursing homes are taking at least three of these drugs.
In APL Bioengineering, researchers have developed materials that can interface with an injured spinal cord and provide a scaffolding to facilitate healing. To do this, scaffolding materials need to mimic the natural spinal cord tissue, so they can be readily populated by native cells in the spinal cord, essentially filling in gaps left by injury. The researchers show how the pores improve efficiency of gene therapies administered locally to the injured tissues, which can further promote tissue regeneration.
Scientists have found an explanation for why Alzheimer’s drugs have limited effectiveness and why patients get much worse after going off of them.
Using a computerized and completely remote training program, researchers have found a way to mitigate negative emotions in children. Results support the link between inhibitory control dysfunction and anxiety/depression. EEG results also provide evidence of frontal alpha asymmetry shifting to the left after completing an emotional version of the training. Computerized cognitive training programs can be highly beneficial for children, not just for academics, but for psychological and emotional functioning during a challenging time in their development.
Van Wagenen Fellowship for 2022-23 awarded to Washington University resident, who will study under Felix Sahm at Heidelberg University Hospital
An analysis of adult human brain tissue reveals over 900 proteins tied to epilepsy. The brain disorder, estimated to afflict more than 3 million Americans, is mostly known for symptoms of hallucinations, dreamlike states, and uncontrolled, often disabling bodily seizures.
Two papers by researchers at Vanderbilt University Medical Center that extend our understanding of the Baylor GSWH scoring system and its application, externally validating it in a different group of patients presenting during a more recent time period in which better acute management techniques are available.
Cohen Veterans Bioscience (CVB) and the European College of Neuropsychopharmacology (ECNP) are pleased to announce the opening of submissions for the 2021 Best Negative Data Prize in Clinical Neuroscience.
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