The mammalian intestinal epithelium constitutes the largest barrier against the external environment and makes flexible responses to various types of stimuli. Epithelial cells are fast-renewed to counteract constant damage and disrupted bar
Pathological scarring and scleroderma, which are the most common conditions of skin fibrosis, pathologically manifest as fibroblast proliferation and extracellular matrix (ECM) hyperplasia. Fibroblast proliferation and ECM hyperplasia lead
Surgical resection, chemotherapy, and radiation are the standard therapeutic modalities for treating cancer. These approaches are intended to target the more mature and rapidly dividing cancer cells. However, they spare the relatively quies
Colorectal cancer (CRC) remains the third most prevalent cancer disease and involves a multi-step process in which intestinal cells acquire malignant characteristics. It is well established that the appearance of distal metastasis in CRC pa
Colorectal cancer (CRC) remains the third most prevalent cancer disease and involves a multi-step process in which intestinal cells acquire malignant characteristics. It is well established that the appearance of distal metastasis in CRC pa
A team of engineers at the University of Colorado Boulder has designed a new class of tiny, self-propelled robots that can zip through liquid at incredible speeds—and may one day even deliver prescription drugs to hard-to-reach places inside the human body.
In APL Bioengineering, researchers design a novel algorithm for controlling implanted insulin pumps that accounts for the unique characteristics of individual patients. Their model, tested using an FDA-approved diabetes computer simulation, proves intraperitoneal (within the abdominal cavity) insulin delivery is fast and closely mimics natural physiological insulin delivery. They developed a model that can account for individual patient differences and validated a pump control algorithm that does not require meal announcement.
Scientists at Wake Forest University School of Medicine have uncovered a novel mechanism that shows increased sugar intake and elevations in blood glucose are sufficient to cause amyloid plaque buildup in the brain, which increases the risk of Alzheimer’s disease.
Researchers in UNC’s School of Medicine’s department of Microbiology and Immunology and the UNC-NC State Joint Department of Biomedical Engineering have developed a new strategy to improve drug-delivery into chronic wounds infections.
Arthrex, a global leader in minimally invasive orthopedic technology, launched a new patient-focused website, ACLTear.com, which illustrates the science of anterior cruciate ligament (ACL) injuries, highlights the benefits of knee preservation technology and provides tools to patients to connect with surgeons performing advanced, minimally invasive ACL procedures.
Biologists have used machine learning, a type of AI, to identify “synthetic extreme” DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and found synthetic DNA sequences with activities that could be useful in biotechnology and medicine.
The American Association of Critical-Care Nurses hosts its annual National Teaching Institute & Critical Care Exposition (NTI) May 22-24 in Philadelphia. NTI -- the world’s largest conference for nurses who care for acutely and critically ill patients -- includes the Critical Care Exposition, the largest and most comprehensive trade show specifically for progressive care and critical care nurses.
CureMD Oncology, a leading provider of all-inclusive technology solutions for community oncology, is delighted to announce its partnership with Palouse Specialty Physicians, a comprehensive cancer care provider in the Pacific Northwest region.
First-generation bioresorbable vascular scaffolds (BVS) may be just as effective as drug-eluting metallic stents, which are currently the standard treatment for heart disease patients undergoing percutaneous coronary intervention (PCI).
Proteins are large, complex molecules that play many critical roles in the body and are produced following the instructions encoded in DNA. By reading their DNA letters, cells produce an intermediate RNA molecule that will give rise to the corresponding protein. Most diseases occur with altered protein levels, which are either a cause or consequence of the condition itself. RNA plays a pivotal role in diseases with altered protein levels by serving as the intermediary messenger between DNA and protein.
Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.
Iowa State University engineers are developing advanced tools for cell manufacturing that could improve the cost and availability of therapeutic cells capable of fighting diseases such as cancers, heart disease, lupus and other autoimmune diseases.
To give the authorities a cross-sectoral view of a city’s nutrient sink status, the researchers identified and analysed a range of waste flows. Their approach distinguished four nested spatial levels: the urban area; the potential territorial recycling system; the country and the international level. Based on that analysis, the researchers focused on the origin and fate of those nutrient-containing waste flows.
A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and biochemistry.
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