Feature Channels: Respiratory Diseases and Disorders

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Released: 30-Jan-2019 4:05 PM EST
South Asians at Risk for Tuberculosis Often Are Not Tested
Rutgers University-New Brunswick

Many South Asian immigrants from countries where tuberculosis (TB) is common do not get tested even though they are at high risk for developing the disease, according to a recent study by Rutgers University and St. Peter’s University Hospital.

Released: 30-Jan-2019 12:00 PM EST
Calorie Restriction Prevents Asthma Symptoms Linked to Inflammation In Mice
Johns Hopkins Medicine

Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet’s fat and sugar content. The researchers also say they found that obesity resulting from a high-calorie diet led to asthma symptoms in the animals by causing lung inflammation, and a drug that blocks inflammation eased those symptoms.

Released: 29-Jan-2019 10:05 AM EST
John Theurer Cancer Center Leading Enrollment for Global Phase 2 WIZARD Study Evaluating DSP-7888 in Patients with Recurrent Glioblastoma
Hackensack Meridian Health

John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center announced today that it is leading enrollment worldwide for WIZARD 201G, a global Phase 2 study in glioblastoma (GBM). The trial, sponsored by Boston Biomedical, is evaluating DSP-7888, an investigational cancer vaccine, in combination with bevacizumab for recurrent disease.

Released: 29-Jan-2019 9:40 AM EST
Nasal Whooping Cough Vaccine Trial Underway at Vanderbilt
Vanderbilt University Medical Center

Vanderbilt vaccine researchers are enrolling adult volunteers in a National Institutes of Health (NIH)-sponsored Phase II clinical trial that will study a next generation pertussis vaccine that may protect people from whooping cough.

23-Jan-2019 12:05 PM EST
Lung Cancer Surgery Patients May Reap Benefits of Larger, More Centralized Hospitals
The Society of Thoracic Surgeons

Regionalizing lung cancer surgery is not only feasible, it’s also effective for patients, resulting in shorter hospital stays and fewer complications

25-Jan-2019 1:00 PM EST
Targeting an ‘Energy Crisis’ in the Treatment of Non-Small Cell Lung Cancer
Rutgers Cancer Institute of New Jersey

Research from Rutgers Cancer Institute of New Jersey examined a potential approach to cancer therapy that disrupts a cancer cell’s ‘fuel supply’ by targeting a cellular survival mechanism known as autophagy. Using laboratory models for LKB1-deficient KRAS-mutant non-small cell lung cancer, they found that autophagy ablation reduced the frequency of tumor initiation and tumor growth in Lkb1-deficient lung tumors.

22-Jan-2019 4:00 PM EST
Fish Oil Does Not Appear to Improve Asthma Control in Teens, Young Adults
American Thoracic Society (ATS)

Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.

24-Jan-2019 2:05 PM EST
Cystic Fibrosis Drug Combo Found Safe and Effective for 2-5 Years Olds
Ann and Robert H. Lurie Children's Hospital of Chicago

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children’s Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation – the most common and severe form of cystic fibrosis.

Released: 24-Jan-2019 12:00 PM EST
Exploring Targeted Therapy for Non-Small Cell Lung Cancer
Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey researcher Sharon R. Pine, PhD, has received a $200,000 Lung Cancer Discovery Award from the American Lung Association to examine potential new treatment options for patients with a sub-type of non-small cell lung cancer.

Released: 22-Jan-2019 1:05 PM EST
IU Study Predicts How Air Pollutants From U.S. Forest Soils Will Increase with Climate Change
Indiana University

Scientists predict that certain regions of the United States will experience higher levels of pollutants that cause smog, acid rain and respiratory problems due changes in forest soils from climate change.

   
Released: 21-Jan-2019 12:55 PM EST
Molecular profiling could catch lung cancer early and lead to new treatments
University College London

The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments, reports a new study led by UCL researchers.

Released: 17-Jan-2019 10:05 AM EST
Air Pollution Increases ER Visits for Breathing Problems, but Rate Depends on Age, Pollutant and Lung Disease
American Thoracic Society (ATS)

As levels of ozone and fine particulate pollution (PM2.5) rise, more patients end up in the ER with breathing problems, according to the largest U.S. study of air pollution and respiratory emergency room visits of patients of all ages. The study was published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

Released: 15-Jan-2019 1:05 PM EST
Prone Positioning Becomes Standard of Care for Patients With ARDS
American Association of Critical-Care Nurses (AACN)

When new guidelines recommend that patients with severe ARDS be face-down most of the day, integrating the logistically challenging repositioning procedure into clinical practice requires a team approach. Christiana Care Health System shares how it made prone positioning the standard of care in its ICUs.

Released: 15-Jan-2019 11:05 AM EST
Save the Date! Cover ATS 2019 in Dallas, Texas
American Thoracic Society (ATS)

They say everything is bigger in Texas and this year Dallas is hosting the ATS 2019 International Conference, the biggest gathering of scientists and clinicians in pulmonary, critical care, and sleep medicine.

Released: 15-Jan-2019 11:05 AM EST
Dr. Frederick L. Grover Receives Prestigious John P. McGovern Compleat Physician Award
The Society of Thoracic Surgeons

Surgeon and researcher Frederick L. Grover, MD, of the University of Colorado, was awarded the 2019 John P. McGovern Compleat Physician Award by the Houston Academy of Medicine and Harris County Medical Society.

Released: 14-Jan-2019 11:05 AM EST
Vanderbilt Set New Heart, Overall Transplant Record in 2018
Vanderbilt University Medical Center

Vanderbilt University Medical Center (VUMC) set a new record for total transplants among its five organ specialties in 2018 with more than 500 transplants.

10-Jan-2019 12:05 PM EST
Complication rates and costs of invasive lung cancer diagnostic tests may be higher than anticipated
University of Texas MD Anderson Cancer Center

Complication rates following invasive diagnostic procedures for lung abnormalities were twice as high in community settings compared to those reporter in lung screening trials, according to an MD Anderson study.

11-Jan-2019 6:05 PM EST
Suicide Risk More Than Quadruples for People with Cancer
Penn State Health

People with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of Medicine researchers.

Released: 10-Jan-2019 5:05 PM EST
Activated PMN exosomes are pathogenic entities that cause destruction in the COPD lung
University of Alabama at Birmingham

Researchers have found a novel, pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in lungs of patients with COPD. These exosomes from activated neutrophils caused COPD damage when they were instilled into the lungs of healthy mice.

Released: 9-Jan-2019 2:05 PM EST
أبحاث الخلايا المُسنّة تتجه إلى تجارب بشرية
Mayo Clinic

روتشستر، مينيسوتا — نشر باحثون من Mayo Clinic، بالتعاون مع باحثين من كلية ويك فورست للطب و مركز العلوم الصحية بجامعة تكساس في سان أنطونيو، نتائج دراسة سريرية حول سلامة وجدوى إزالة خلايا مُسنّة من مجموعة صغيرة من المرضى المصابين بالتليف الرئوي. وعُرِضت نتائج الدراسة في مجلة الطب الحيوي "إي بايو مديسن" EBioMedicine.

Released: 8-Jan-2019 4:05 PM EST
Case Western Reserve’s John “Chip” Tilton, MD, Secures School of Medicine’s Fourth Falk Catalyst Award
Case Western Reserve University

John “Chip” Tilton, MD, of Case Western Reserve University School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton’s project will address a major challenge in developing nanoscale therapeutics: finding ways to deliver them to the right location inside the body.

4-Jan-2019 9:30 AM EST
Having more than one chronic disease amplifies costs of diseases, study finds
PLOS

Having two or more non-communicable diseases (multimorbidity) costs the country more than the sum of those individual diseases would cost, according to a new study published this week in PLOS Medicine by Tony Blakely from the University of Otago, New Zealand, and colleagues.

Released: 8-Jan-2019 11:05 AM EST
# 1 in NIH Funding for Second Consecutive Year
University of Pennsylvania School of Nursing

With $13.4 million dollars in awards from the National Institutes of Health (NIH), the University of Pennsylvania School of Nursing (Penn Nursing) retains its top spot for research funding for the 2018 fiscal year, among other schools of nursing. This is the second consecutive year Penn Nursing has earned first place.

Released: 31-Dec-2018 1:05 PM EST
Stop smoking without packing on the pounds
Ohio State University Wexner Medical Center

Smoking is a hard habit to kick but when you do, the health benefits are almost immediate. As you re-invent yourself as a non-smoker, here are three straightforward ways to combat weight gain and keep you distracted while coming off that smoking habit.

Released: 27-Dec-2018 4:05 PM EST
My Cold Is Gone, So Why Am I Still Coughing?
Ohio State University Wexner Medical Center

One of the classic cold symptoms is a cough. Usually after a week or so, the cold runs its course and most of the symptoms go away. But for some people, the cough remains. So why do we cough and what can we do about it? Here are five things you should know about that persistent cough.

Released: 26-Dec-2018 10:35 AM EST
A Resolution for Good Health
Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute experts share more about the importance of preventative screenings for colorectal and lung cancers.

19-Dec-2018 12:05 PM EST
Yale Cancer Center scientists advise caution in immunotherapy research
Yale Cancer Center/Smilow Cancer Hospital

In a new study by Yale Cancer Center (YCC), scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caution should be exercised as we continue to better understand the biology of these new therapeutic targets.

Released: 20-Dec-2018 7:05 AM EST
Early detection: Chemists discover new signatures to identify cystic fibrosis in infants sooner with better reliability
McMaster University

Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis (CF), a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.

17-Dec-2018 10:05 AM EST
In Just Six Months, Exercise May Help Those with Thinking Problems
American Academy of Neurology (AAN)

Getting the heart pumping with aerobic exercise, like walking or cycling for 35 minutes three times a week, may improve thinking skills in older adults with cognitive impairments, according to a study published in the December 19, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. After six months of exercise, study participants’ scores on thinking tests improved by the equivalent of reversing nearly nine years of aging.

   
Released: 18-Dec-2018 12:05 PM EST
With a Focus on High-Risk Patients, SLU Researcher Eyes Eliminating TB for Good
Saint Louis University Medical Center

A focus on high-risk tuberculosis patients may be the answer to stalled progress in stamping out the illness in the United States.

Released: 18-Dec-2018 10:00 AM EST
Nearly 1 In 5 Tibetan Refugee Schoolchildren Has Tuberculosis Infection, Johns Hopkins Study Finds
Johns Hopkins Medicine

In a tuberculosis screening and treatment initiative covering the entire population of Tibetan refugee schoolchildren in northern India, a team directed by researchers at Johns Hopkins Medicine and the University of Wisconsin says it has found not only a startlingly high prevalence of TB disease and infection, but also a potentially workable strategy to eliminate the disease in a large, high-risk group.

14-Dec-2018 4:05 PM EST
Your Postal Code May Influence Your Health
McMaster University

Researchers at McMaster University have identified trends linking health and lifestyle factors like access to public transit, the variety of fresh fruits and vegetables in grocery stores, the prices of popular foods, the availability and prices of cigarettes and alcohol, and the promotion, or lack thereof, of healthy foods in restaurants. The study findings are based on detailed data collected across Canada’s 10 provinces.

Released: 17-Dec-2018 10:00 AM EST
Study Affirms Geographic Discrimination in Allocating Lungs for Transplant
Johns Hopkins Medicine

Results of a medical records study of more than 7,000 patients awaiting a lung transplant in the United States affirm the basis of a court filing in 2017 that called the organ allocation system geographically “rigged” in some regions of the nation.

Released: 14-Dec-2018 10:05 AM EST
A Holiday Gift to Primary Care Doctors: Proof That There’s Not Enough Time For Everything They’re Expected to Do
Michigan Medicine - University of Michigan

The average primary care doctor needs to work six more hours a day than they already do, in order to make sure their patients get all the preventive and early-detection care they deserve, a new study finds. Fortunately, the new study was written as a parody -- no one is asking doctors to work past midnight every night. At least, not yet.

Released: 13-Dec-2018 1:05 PM EST
Integrated Data Vital in Stopping Spread of TB
University of Manitoba

Manitoba has the highest provincial incident rate of active tuberculosis (TB) in Canada, and stopping its spread depends on, among other things, the availability of high-quality, comprehensive data to ensure early and complete treatment, according to a new study by the Manitoba Centre for Health Policy (MCHP) at the University of Manitoba.

Released: 12-Dec-2018 4:05 PM EST
Blood Test Could Lead to Cystic Fibrosis Treatment Tailored to Each Patient
Ann and Robert H. Lurie Children's Hospital of Chicago

Researchers at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression ultimately could help predict disease severity and treatment response, and lead to therapies tailored to each patient’s precise biology.

Released: 12-Dec-2018 10:05 AM EST
Two Young Women with Cystic Fibrosis Reflect on their Care at Robert Wood Johnson Medical School's Nationally Ranked CF Center
Rutgers Robert Wood Johnson Medical School

Julia and Cameron were born with cystic fibrosis (CF), an inherited, chronic, progressive disease that affects respiratory and pancreatic function. Both artists and athletes, they refuse to let the disease define their lives, and consider themselves integral partners in the care they receive at the comprehensive Cystic Fibrosis Center at Rutgers Robert Wood Johnson Medical School, one of only three accredited CF centers in New Jersey. In 2016, the CF Center ranked highest nationally and in New Jersey in a composite score for lung function and nutritional status.

Released: 11-Dec-2018 2:05 PM EST
Mayo 研究人员:口服阿哌沙班治疗癌症患者血栓安全有效
Mayo Clinic

Mayo Clinic研究人员发现,一种在癌症治疗过程中用于治疗患者血栓的口服药物——阿哌沙班是安全有效的。 与低分子量的肝素相比,这种药物的大出血事件和血栓复发率都较低。这些研究结果由 Mayo Clinic 心脏病学专家、医学博士Robert McBane II在在美国血液学学会年会上提出。

Released: 10-Dec-2018 1:30 PM EST
Health Experts Call on EPA to Reverse Decision to Eliminate Pollutant-Specific Panels
American Thoracic Society (ATS)

In a letter to EPA Acting Administrator Andrew Wheeler members of the scientific community expressed concern about the agency’s decision to dissolve pollutant-specific advisory panels, including one charged with setting the National Ambient Air Quality Standard or NAAQS for airborne particulate matter or PM.

9-Dec-2018 11:00 AM EST
MD Anderson study shows key enzyme linked to therapy resistance in deadly lung cancer
University of Texas MD Anderson Cancer Center

Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC).

4-Dec-2018 4:00 PM EST
Vitamin C May Reduce Harm to Infants’ Lungs Caused by Smoking During Pregnancy;
American Thoracic Society (ATS)

Vitamin C may reduce the harm done to lungs in infants born to mothers who smoke during their pregnancy, according to a randomized, controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

Released: 6-Dec-2018 11:05 AM EST
PET imaging tracks antibiotic penetration into infected brain lesions for treatment of TB meningitis
National Institute of Biomedical Imaging and Bioengineering

TB meningitis causes life-threatening inflammation of the brain, which is difficult to treat due to the inability of drugs to penetrate the blood brain barrier. Researchers used PET imaging to measure antibiotic concentrations in infected brains with the goal of optimizing TB meningitis treatment.

   
Released: 6-Dec-2018 10:00 AM EST
PET Scans to Optimize Tuberculosis Meningitis Treatments and Personalize Care, Study Finds
Johns Hopkins Medicine

Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain—or tuberculosis meningitis (TBM)—is often deadly, always hard to treat, and a particular threat to young children.

Released: 5-Dec-2018 12:05 PM EST
Tuberculosis survives by using host system against itself
University of Notre Dame

In a new study published in the Journal of Experimental Medicine, scientists at the University of Notre Dame have discovered that the pathogen Mycobacterium tuberculosis (MTB) releases RNA into infected cells.

   
Released: 5-Dec-2018 12:05 PM EST
Memory B cells in the lung may be important for more effective influenza vaccinations
University of Alabama at Birmingham

Researchers show that lung-resident memory B cells establish themselves in the lung soon after influenza infection in mice. Those lung memory B cells respond more quickly to produce antibodies against influenza after re-infection, and establishment requires a local antigen encounter in the lung.

Released: 5-Dec-2018 6:05 AM EST
What Can Hair Tell About? A Non-Invasive Diagnostics of Diseases Is Discovered at SUSU
South Ural State University

It is an often case that one’s health and life depend on as quick a disease is found. That is why today the ways of quick and effective revealing of a disease is one of the most important directions in medicine.

Released: 4-Dec-2018 6:05 PM EST
Bisphenol A (BPA) and Phthalates; miRNAs and Nephrotoxicity; and More Featured in December 2018 Toxicological Sciences
Society of Toxicology

Description: Papers on BPA and phthalates; EDCs and obesity; air pollution; respiratory outcomes in deployed soldiers; and miRNAs featured in latest issue of Toxicological Sciences.

   
Released: 4-Dec-2018 2:05 PM EST
Visualizing vitals through video
Penn State College of Engineering

Conrad Tucker, associate professor of engineering design and industrial engineering, demonstrates how a mobile-based application will use a cellphone camera and computer vision techniques to capture pulse rate. Tucker and his team use a Masimo Rad-97, a compact, portable patient monitoring device which measures pulse rate, respiratory rate, oxygen saturation, perfusion index, total hemoglobin and pleth variability index, as a ground to compare the application's captured data.



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