This one-atom chemical reaction could transform drug discovery
Osaka UniversityPharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production.
Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production.
New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.
A UCLA-led study provides the first scientific evidence that brick and mortar pharmacies in Northern Mexican tourist towns are selling counterfeit pills containing fentanyl, heroin, and methamphetamine. These pills are sold mainly to US tourists, and are often passed off as controlled substances such as Oxycodone, Percocet, and Adderall.
The FDA cleared SCINTIX biology-guided radiotherapy to treat patients with lung and bone tumors. These tumors may arise from primary cancers or from metastatic lesions spread from other cancers in the body. The breakthrough nature of SCINTIX technology lies in its ability to detect and then treat multiple moving tumors.
Despite concerns over antimicrobial resistance, global antimicrobial use in animals could increase by 8% by 2030.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).
Below are some of the latest articles that have been added to the Surgery and the Transplantation channels on Newswise, a free source for journalists.
Reductions in violence are seen in individuals using Beta adrenergic-blocking agents (β-blockers) compared with periods that they are not taking the medication, in a study published January 31st in the open access journal PLOS Medicine. If the findings are confirmed by other studies, β-blockers could be considered as a way to manage aggression and hostility in individuals with psychiatric conditions.
A new survey finds that men who would be potential users of HIV pre-exposure prophylaxis (PrEP) medication prefer long-acting injections over pills, but rank side effects and costs as the most important issues for them in considering whether to take PrEP.
UC San Diego scientists developed an artificial intelligence tool that could accelerate the development of new high affinity antibody drugs.
Inmazeb (REGN-EB3), developed by Regeneron, is a three-antibody cocktail designed to target the Ebola virus glycoprotein. The drug was first approved for clinical use in October 2020, but its exact mechanism of action has remained unclear.
Malgré les recommandations, le traitement de première intention de l'état de mal épileptique est souvent inapproprié. Des études suggèrent que jusqu'à deux tiers des patients reçoivent des doses subcliniques de benzodiazépines, soit avant d'arriver à l'hôpital, soit pendant un traitement hospitalier d'urgence. Existe-t-il des solutions ?
A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has breathed new life into an existing drug — combatting a type of blood cancer called T-cell acute lymphoblastic leukaemia, or T-ALL. The drug, called PIK-75, was initially discovered over a decade ago but was dismissed in favour of newer ones. Now, it has made a comeback that deems it unmissable — the researchers established that the drug could block not just one but two crucial cancer-causing pathways of T-ALL, enabling them to develop new treatments that could effectively stem the disease.
Inaccurately recording the start of anesthesia care during a procedure is common and results in significant lost billing time for anesthesia practices and medical centers, suggests a study being presented at the American Society of Anesthesiologists’ ADVANCE 2023, the Anesthesiology Business Event.
Expanding anesthesiology residency programs — even in the absence of federal funding — may help medical institutions save staffing costs and address projected shortages of anesthesia care professionals, suggests a first-of-its-kind study being presented at the American Society of Anesthesiologists’ ADVANCE 2023, the Anesthesiology Business Event.
The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.
GRF's leadership awards will be presented at the Glaucoma 360 Annual Gala on February 2, 2023 at the iconic Westin St. Francis Hotel in San Francisco.
Santen will receive GRF’s highest honor, the Catalyst Award, at the Glaucoma 360 Annual Gala on February 2, 2023, in San Francisco.
Long-term treatment of healthy middle-aged mice with a cancer drug increases lifespan by 10% on average, equivalent to 3 years.