A new study published Jan. 13 in Science reports that Epstein-Barr virus infection – known for causing mononucleosis or “mono,” could be a primary cause for multiple sclerosis.
The human immune system, that marvel of complexity, subtlety, and sophistication, includes a billion-year-old family of proteins used by bacteria to defend themselves against viruses, scientists at Dana-Farber Cancer Institute and in Israel have discovered.
An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.
A new, targeted therapy, developed by researchers from the Azrieli Faculty of Medicine of Bar-Ilan University, the Albert Einstein College of Medicine, the University of Houston, and the pharmaceutical company Equillium, together with several other academic collaborators, inhibits specific immune cells associated with lupus nephritis, and was effective in improving kidney inflammation in animal models of lupus and lupus nephritis. The new approach could serve as an alternative to current treatments targeting multiple immune cells, and provide a more effective and potentially personalized remedy for lupus nephritis. The development was recently reported in the Journal of Clinical Investigation.
Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures. However, little is known about how tertiary lymphoid structures form. In a new article published in Immunity, Moffitt Cancer Center researchers report on the molecular and cellular mechanisms that control tertiary lymphoid structure formation within tumors.
Researchers at Penn Medicine have discovered a new, more effective method of preventing the body’s own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy’s effectiveness.
There is growing evidence that the currently available MRNA vaccines provide some protection against the Omicron variant (B.1.1.529) of the SARS-COV-2 virus, the coronavirus that causes COVID-19. According to the CDC, preliminary results for Omicron from South Africa showed that the Pfizer vaccine provided 70% protection against COVID-19 hospitalization and 33% against infection, during the current Omicron wave. Granted, the protection is reduced compared with the Delta variant (93% for hospitalization and 80% for infection).
Summaries of recent Fred Hutch research findings and other news.
An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.
Scientists at La Jolla Institute for Immunology (LJI) and Charles River Laboratories International, Inc., are launching a new project to uncover exactly how different cells in the human immune system respond to SARS-CoV-2, the virus that causes COVID-19.
مدينة روتشستر، ولاية مينيسوتا - تُظهر أبحاث مايو كلينك أن إضافة علاج الحمض النووي الريبوزي المرسال (mRNA) يحسن الاستجابة للعلاج المناعي للسرطان لدى المرضى الذين لم يستجيبوا للعلاج. ويستخدم العلاج المناعي جهاز المناعة في الجسم للوقاية من السرطان ومكافحته والقضاء عليه. كما نُشرت الدراسة في أبحاث مناعة السرطان، إحدى مجلات الجمعية الأمريكية لأبحاث السرطان.
妙佑医疗国际(Mayo Clinic)的研究表明，添加信使的RNA（核糖核酸）或称mRNA疗法可以改善对治疗无反应的患者对癌症免疫疗法的应答。免疫疗法利用人体的免疫系统来预防、控制和消除癌症。这项研究发表于美国癌症研究协会的期刊《癌症免疫学研究》。
a adição da terapia com RNA mensageiro ou mRNA, melhora a reposta da imunoterapia ao câncer nos pacientes que não estavam respondendo ao tratamento, demonstra uma pesquisa da Mayo Clinic. A imunoterapia utiliza o sistema imunológico para prevenir, controlar e eliminar o câncer. O estudo está publicado no Cancer Immunology Research, uma revista médica da Associação Americana para Pesquisa do Câncer.
Añadir la terapia con ARN mensajero mejora la respuesta a la inmunoterapia contra el cáncer en los pacientes que no respondieron al tratamiento, revela un estudio de Mayo Clinic. La inmunoterapia utiliza al sistema inmunitario para prevenir, controlar y eliminar el cáncer. El estudio se publicó en Cancer Immunology Research (Investigación Inmunológica sobre el Cáncer), revista de la Asociación Americana de Investigación sobre el Cáncer.
A first-in-kind immune-modulating drug that arose from decades of basic research at UT Southwestern Medical Center has received approval from the U.S. Food and Drug Administration as a new treatment for adults with a form of myasthenia gravis. This rare and chronic autoimmune disease is characterized by debilitating and potentially life-threatening muscle weakness.
Scientists at the La Jolla Institute for Immunology (LJI) have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.
MED-CU has invented a Personalized Probiotics (Dispensing) Machine to deliver live microorganisms that have health benefits to treat patients with unclear health problems and those with microbial imbalances or “dysbiosis”.
The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.
They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system.
What if the key to aging well lies in reprogramming immune system cells to strengthen them against infections and cancer? Researchers at UT Southwestern are working to find out.
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